{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T22:05:38Z","timestamp":1790633138897,"version":"4.1.0"},"reference-count":35,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2021,3,8]],"date-time":"2021-03-08T00:00:00Z","timestamp":1615161600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2021,3,8]],"date-time":"2021-03-08T00:00:00Z","timestamp":1615161600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Trop Med Health"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Toxoplasmosis is an infectious disease caused by a protozoan parasite named <jats:italic>Toxoplasma gondii<\/jats:italic> (<jats:italic>T.gondii<\/jats:italic>). Pregnant women are considered one of the risk groups. The objective of this retrospective study is to provide an updated estimate of the seroprevalence of anti-<jats:italic>T. gondii<\/jats:italic> antibodies among a group of Moroccan pregnant women monitored at the Parasitology Laboratory of the National Institute of Hygiene in Rabat in Morocco.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>Serum samples were tested for the presence of specific anti-<jats:italic>T. gondii<\/jats:italic> immunoglobulin G (IgG) and immunoglobulin M (IgM) antibodies using indirect enzyme-linked immunosorbent assay (ELISA). Anti-<jats:italic>Toxoplasma<\/jats:italic> IgM- and IgG-positive cases were also evaluated with the anti-<jats:italic>Toxoplasma<\/jats:italic> IgG avidity test. All cases were evaluated according to the age, parity, and historical of abortion.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Among 677 pregnant women, 94.1% (637\/677) were serologically screened for the first time and therefore had no knowledge of their serological status, and only 5.9% (40\/677) were screened for the second or third time. The overall anti-<jats:italic>T. gondii<\/jats:italic> IgG and IgM seropositivity among the 637 pregnant women included in the study analysis was 43% (274\/637) and 3.9% (25\/637), respectively. The use of the IgG avidity test allowed excluding recent infection among 83% of cases with IgG and IgM positive sera. The mean age was 29.4 \u00b1 6.3 years. The result of the bivariate analysis revealed that the age influenced significantly the seroprevalence rate, while the parity and the existence of previous spontaneous abortion did not have any significant statistical correlation with seropositivity to <jats:italic>T. gondii<\/jats:italic>.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>This study shows that 43% of pregnant women were positive and 57% of them had no antibody against the <jats:italic>T. gondii<\/jats:italic> infection. However, the pregnancy follow-up and the counseling of pregnant women remain essential for the prevention of congenital toxoplasmosis.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s41182-021-00311-5","type":"journal-article","created":{"date-parts":[[2021,3,8]],"date-time":"2021-03-08T13:04:21Z","timestamp":1615208661000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Toxoplasma gondii seroprevalence among pregnant women in Rabat, Morocco"],"prefix":"10.1186","volume":"49","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8246-6848","authenticated-orcid":false,"given":"Majda","family":"Laboudi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zoubida","family":"Taghy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oussama","family":"Duieb","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fran\u00e7ois","family":"Peyron","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abderrahim","family":"Sadak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,3,8]]},"reference":[{"key":"311_CR1","first-page":"65","volume":"470","author":"H Yera","year":"2015","unstructured":"Yera H, Paris L, Bastien P, Candolfi E. 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All data used in this study cannot be directly associated with any individual. Therefore, no consent or ethical clearance is applicable for this study. The confidentiality of the details of the subjects was assured for all pregnant women followed up in our laboratory.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"21"}}