{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T09:57:11Z","timestamp":1768903031458,"version":"3.49.0"},"reference-count":9,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,6,18]],"date-time":"2025-06-18T00:00:00Z","timestamp":1750204800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2025,6,18]],"date-time":"2025-06-18T00:00:00Z","timestamp":1750204800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["CVIR Endovasc"],"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:sec>\n            <jats:title>Background<\/jats:title>\n            <jats:p>Persistent sciatic artery (PSA) is a rare congenital anomaly associated with various complications, including atherosclerotic changes and aneurysms. These changes can cause limb ischemia, thrombosis, distal embolization of the PSA, rupture of aneurysms, buttock pain, and sciatica due to compression of adjacent tissues.<\/jats:p>\n            <jats:p>Acute limb ischemia (ALI) is a life-threatening condition. Treatment of ALI includes surgical and endovascular treatments (EVT); EVT includes catheter-directed thrombolysis (CDT) and angioplasty, with thrombolysis being highly effective. In Japan, urokinase is the only insurance-covered thrombolytic agent approved for ALI treatment; however, it is currently unavailable due to manufacturing issues.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Case presentation<\/jats:title>\n            <jats:p>This case report details the treatment of two women (aged 89 and 82\u00a0years) with ALI associated with PSA. In both cases, reperfusion was achieved without CDT and stent grafts were deployed across the PSA aneurysm. The final angiogram showed that the PSA aneurysms had disappeared, and the vessel runoff was maintained. Both patients were successfully discharged from the hospital and experienced no complications over the next 6\u00a0months.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p>Two patients with ALI with PSA were treated with EVT without CDT. These cases suggest that EVT without CDT may rescue ALI caused by PSA. Moreover, no standard treatment for sciatic artery remnants has been established. Endovascular treatment with stent grafts may be an option for older patients.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1186\/s42155-025-00568-5","type":"journal-article","created":{"date-parts":[[2025,6,18]],"date-time":"2025-06-18T06:30:33Z","timestamp":1750228233000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Endovascular treatment of acute limb ischemia for persistent sciatic artery aneurysms: a report of 2 cases"],"prefix":"10.1186","volume":"8","author":[{"given":"Eiji","family":"Koyama","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1913-6894","authenticated-orcid":false,"given":"Kazuki","family":"Tobita","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shun","family":"Sawada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Motoaki","family":"Kai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hirokazu","family":"Mityashita","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shigeru","family":"Saito","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,6,18]]},"reference":[{"issue":"1","key":"568_CR1","doi-asserted-by":"publisher","first-page":"44","DOI":"10.3400\/avd.cr.16-00119","volume":"10","author":"K Morisaki","year":"2017","unstructured":"Morisaki K, Yamaoka T, Iwasa K, Kuma S, Okazaki J. Persistent sciatic artery aneurysm with limb ischemia: A report of two cases. Ann Vasc Dis. 2017;10(1):44\u20137. https:\/\/doi.org\/10.3400\/avd.cr.16-00119.","journal-title":"Ann Vasc Dis"},{"issue":"1","key":"568_CR2","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1055\/s-0042-1745850","volume":"32","author":"D Kretzschmar","year":"2022","unstructured":"Kretzschmar D, Thieme M, Aschenbach R, Schulze PC, M\u00f6bius-Winkler S. A very rare cause of thrombotic peripheral occlusion. Int J Angiol. 2022;32(1):75\u201380. https:\/\/doi.org\/10.1055\/s-0042-1745850.","journal-title":"Int J Angiol"},{"issue":"1","key":"568_CR3","doi-asserted-by":"publisher","first-page":"128","DOI":"10.1016\/j.jvscit.2020.09.012","volume":"7","author":"T Hayashi","year":"2020","unstructured":"Hayashi T, Mine T, Mizushima S, Fujii M, Iseki Y, Yamada N, et al. Total endovascular repair for a persistent sciatic artery aneurysm with widespread limb-threatening arterial occlusion. J Vasc Surg Cases Innov Tech. 2020;7(1):128\u201332. https:\/\/doi.org\/10.1016\/j.jvscit.2020.09.012.","journal-title":"J Vasc Surg Cases Innov Tech"},{"issue":"1","key":"568_CR4","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1053\/j.semvascsurg.2008.12.003","volume":"22","author":"RB Rutherford","year":"2009","unstructured":"Rutherford RB. Clinical staging of acute limb ischemia as the basis for choice of revascularization method: when and how to intervene. Semin Vasc Surg. 2009;22(1):5\u20139. https:\/\/doi.org\/10.1053\/j.semvascsurg.2008.12.003.","journal-title":"Semin Vasc Surg"},{"issue":"5","key":"568_CR5","doi-asserted-by":"publisher","first-page":"585","DOI":"10.1016\/j.ejvs.2009.01.014","volume":"37","author":"IM van Hooft","year":"2009","unstructured":"van Hooft IM, Zeebregts CJ, van Sterkenburg SM, de Vries WR, Reijnen MM. The persistent sciatic artery. Eur J Vasc Endovasc Surg. 2009;37(5):585\u201391. https:\/\/doi.org\/10.1016\/j.ejvs.2009.01.014.","journal-title":"Eur J Vasc Endovasc Surg"},{"issue":"12","key":"568_CR6","doi-asserted-by":"publisher","first-page":"1997","DOI":"10.1016\/j.jvir.2014.08.020","volume":"25","author":"H Sato","year":"2014","unstructured":"Sato H, Nakai M, Sato M, Ikoma A, Nishimura Y. Retrograde popliteal endovascular stent-graft repair for a growing persistent sciatic artery aneurysm (type IIa): case report and review of the literature. J Vasc Interv Radiol. 2014;25(12):1997\u20132000. https:\/\/doi.org\/10.1016\/j.jvir.2014.08.020.","journal-title":"J Vasc Interv Radiol"},{"issue":"3","key":"568_CR7","doi-asserted-by":"publisher","first-page":"264","DOI":"10.1177\/1538574419899034","volume":"54","author":"N Charisis","year":"2020","unstructured":"Charisis N, Giannopoulos S, Tzavellas G, Tassiopoulos A, Koullias G. Endovascular treatment of persistent sciatic artery aneurysms with primary stenting: A systematic review of the literature. Vasc Endovascular Surg. 2020;54(3):264\u201371. https:\/\/doi.org\/10.1177\/1538574419899034.","journal-title":"Vasc Endovascular Surg"},{"issue":"2","key":"568_CR8","doi-asserted-by":"publisher","first-page":"654","DOI":"10.1016\/j.jvs.2019.05.031","volume":"71","author":"EB Veenstra","year":"2020","unstructured":"Veenstra EB, van der Laan MJ, Zeebregts CJ, de Heide EJ, Kater M, Bokkers RPH. A systematic review and meta-analysis of endovascular and surgical revascularization techniques in acute limb ischemia. J Vasc Surg. 2020;71(2):654-68.e3. https:\/\/doi.org\/10.1016\/j.jvs.2019.05.031.","journal-title":"J Vasc Surg"},{"key":"568_CR9","doi-asserted-by":"publisher","first-page":"175394472092457","DOI":"10.1177\/1753944720924575","volume":"14","author":"K Fukuda","year":"2020","unstructured":"Fukuda K, Yokoi Y. Endovascular approach for acute limb ischemia without thrombolytic therapy. Ther Adv Cardiovasc Dis. 2020;14:1753944720924575. https:\/\/doi.org\/10.1177\/1753944720924575.","journal-title":"Ther Adv Cardiovasc Dis"}],"container-title":["CVIR Endovascular"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s42155-025-00568-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s42155-025-00568-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s42155-025-00568-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,18]],"date-time":"2025-06-18T06:30:33Z","timestamp":1750228233000},"score":1,"resource":{"primary":{"URL":"https:\/\/CVIRendovasc.springeropen.com\/articles\/10.1186\/s42155-025-00568-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6,18]]},"references-count":9,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["568"],"URL":"https:\/\/doi.org\/10.1186\/s42155-025-00568-5","relation":{},"ISSN":["2520-8934"],"issn-type":[{"value":"2520-8934","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,6,18]]},"assertion":[{"value":"5 February 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 May 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 June 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Written informed consent was obtained from the patient for publication of this case report and any accompanying images.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Written informed consent was obtained from the patient for publication of this case report and any accompanying images.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"53"}}