{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T03:31:03Z","timestamp":1787110263215,"version":"build-2736575974"},"reference-count":6,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T00:00:00Z","timestamp":1787097600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T00:00:00Z","timestamp":1787097600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["CVIR Endovasc"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>This prospective, multicenter, single-arm clinical trial evaluated the safety and efficacy of the Jetstream Atherectomy System in 72 Chinese patients with calcified femoropopliteal artery occlusive disease (FPOAD).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and methods<\/jats:title>\n                    <jats:p>The study protocol was approved by the institutional review boards of all participating centers, and all participants provided written informed consent. The primary endpoints were 30-day major adverse events (MAE) and changes in angiographic stenosis. Secondary endpoints included vessel patency, clinical improvement, and adverse events during follow-up.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The study cohort had a mean age of 67.5\u2009\u00b1\u20099.0 years, with a high prevalence of hypertension (79.2%) and diabetes (37.5%). Severe calcification (PACSS, Peripheral Arterial Calcium Scoring System, grade 3\u20134) was present in 43.1% of lesions. Technical success (\u2264\u200930% residual stenosis) was achieved in 91.7% of cases. The 30-day major adverse events (MAE) rate was 1.4%, with one target lesion revascularization (TLR), and no deaths or amputations were recorded. Mean stenosis was reduced from 87.8 to 48.5%, with a mean lumen gain of 40.2%. At 12 months, primary patency was 68.4%; secondary patency was 89.7%. Clinical improvement was evidenced by an increase in the mean ankle-brachial index (ABI) from 0.52\u2009\u00b1\u20090.15 to 0.76\u2009\u00b1\u20090.18, and 91.7% (66\/72) of patients showed an improvement of at least one Rutherford class after 1 year.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This study confirms the Jetstream system\u2019s clinical value in Chinese FPOAD patients. Its combination of mechanical cutting and aspiration makes it particularly suitable for Asian-specific calcified lesions, achieving favorable clinical outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s42155-026-00734-3","type":"journal-article","created":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T03:10:54Z","timestamp":1787109054000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Clinical efficacy and safety of the Jetstream Atherectomy System in Chinese Patients with femoropopliteal artery occlusive disease"],"prefix":"10.1186","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0012-847X","authenticated-orcid":false,"given":"Xin","family":"Jia","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhong","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoming","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weiguo","family":"Fu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinwu","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongkun","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,8,19]]},"reference":[{"key":"734_CR1","doi-asserted-by":"publisher","first-page":"e32","DOI":"10.1016\/j.jvs.2011.09.001","volume":"54","author":"TW Rooke","year":"2011","unstructured":"Rooke TW, Hirsch AT, Misra S, et al. 2011 ACCF\/AHA focused update of the guideline for the management of patients with peripheral artery disease (updating the 2005 guideline): a report of the American College of Cardiology Foundation\/American Heart Association Task Force on Practice Guidelines: developed in collaboration with the Society for Cardiovascular Angiography and Interventions, Society of Interventional Radiology, Society for Vascular Medicine, and Society for Vascular Surgery. J Vasc Surg. 2011;54:e32-58.","journal-title":"J Vasc Surg"},{"issue":"1","key":"734_CR2","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1186\/s42155-025-00626-y","volume":"8","author":"T Haraguchi","year":"2025","unstructured":"Haraguchi T, Tsujimoto M, Leung RW, Chang Y, Kasai Y, Hachinohe D, et al. FRAP-CROSS technique: fracking and Rendezvous-PIERCE for intracalcium crossing in femoropopliteal diffuse calcified occlusions. CVIR Endovasc. 2025;8(1):103.","journal-title":"CVIR Endovasc"},{"key":"734_CR3","unstructured":"Writing group of Chinese expert recommendations on the diagnosis and treatment of atherosclerotic disease of the extremities in the elderly (2012). Chin J Geriatr 2013;32:121\u2013131."},{"key":"734_CR4","doi-asserted-by":"publisher","first-page":"520","DOI":"10.1016\/j.avsg.2010.10.007","volume":"25","author":"S Sixt","year":"2011","unstructured":"Sixt S, Scheinert D, Rastan A, et al. One-year outcome after percutaneous rotational and aspiration atherectomy in infrainguinal arteries in patient with and without type 2 diabetes mellitus. Ann Vasc Surg. 2011;25:520\u20139.","journal-title":"Ann Vasc Surg"},{"issue":"5 Pt A","key":"734_CR5","doi-asserted-by":"publisher","first-page":"506","DOI":"10.1016\/j.carrev.2017.12.015","volume":"19","author":"WA Gray","year":"2018","unstructured":"Gray WA, Garcia LA, Amin A, et al. Jetstream atherectomy system treatment of femoropopliteal arteries: results of the post-market JET registry. Cardiovasc Revasc Med. 2018;19(5 Pt A):506\u201311.","journal-title":"Cardiovasc Revasc Med"},{"issue":"2","key":"734_CR6","doi-asserted-by":"publisher","first-page":"240","DOI":"10.1177\/15266028211045700","volume":"29","author":"O Iida","year":"2022","unstructured":"Iida O, Urasawa K, Shibata Y, et al. Clinical safety and efficacy of rotational atherectomy in Japanese patients with peripheral arterial disease presenting femoropopliteal lesions: the J-SUPREME and J-SUPREME II trials. J Endovasc Ther. 2022;29(2):240\u20137.","journal-title":"J Endovasc Ther"}],"container-title":["CVIR Endovascular"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s42155-026-00734-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s42155-026-00734-3","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s42155-026-00734-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T03:10:56Z","timestamp":1787109056000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1186\/s42155-026-00734-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,19]]},"references-count":6,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["734"],"URL":"https:\/\/doi.org\/10.1186\/s42155-026-00734-3","relation":{},"ISSN":["2520-8934"],"issn-type":[{"value":"2520-8934","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,19]]},"assertion":[{"value":"27 April 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 July 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 August 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and\/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. All procedures performed in studies involving animals were in accordance with the ethical standards of the institution or practice at which the studies were conducted.Informed consent was obtained from all individual participants included in the study.","order":1,"name":"Ethics","label":"Ethics approval and\u00a0consent to participate","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Consent for publication was obtained for every individual person\u2019s data included in the study.","order":2,"name":"Ethics","label":"Consent for publication","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare that they have no conflict of interest.","order":3,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"104"}}