{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T22:42:55Z","timestamp":1780353775671,"version":"3.54.1"},"reference-count":16,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,11,11]],"date-time":"2024-11-11T00:00:00Z","timestamp":1731283200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,11,11]],"date-time":"2024-11-11T00:00:00Z","timestamp":1731283200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Adv Rheumatol"],"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Takayasu arteritis (TA) and tuberculosis (TB) share similar histopathological and immunological characteristics. Studies comparing patients with TA with or without active or latent TB infection (LTBI) have revealed some differences in clinical and angiographic profiles. Patient with TA and history of TB exhibited more constitutional symptoms and structural damage to the aorta. This study compared the clinical and radiological features of patients with TA with and without active TB or LTBI.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>We retrospectively analyzed the data of patients with TA at a public tertiary referral outpatient clinic in northeast Brazil from January 2017 to June 2022. Comparisons of clinical features were made according to the presence of TB.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Fifty patients met the eligibility criteria, and a association with TB was identified in 20 (40%) patients (active TB in six and LTBI in 14). There was a predominance of females, and the average age of patients was 40 years. Weight loss was more common in patients with TA and TB (<jats:italic>p<\/jats:italic>\u2009=\u20090.005). No significant intergroup differences were noted in terms of comorbidities, medications, erythrocyte sedimentation rates, or C-reactive protein levels. Significant differences were found in abdominal aortic involvement (25% of patients with TA and TB vs. 11.4% in subjects with TA without TB; <jats:italic>p<\/jats:italic>\u2009=\u20090.013). Dilations and aneurysms were significantly more common in patients with TA and TB (<jats:italic>p<\/jats:italic>\u2009=\u20090.009 and <jats:italic>p<\/jats:italic>\u2009=\u20090.027, respectively).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>Patients with TA and TB have a higher prevalence of dilatation and aneurysms, most commonly in the abdominal aorta.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s42358-024-00424-5","type":"journal-article","created":{"date-parts":[[2024,11,11]],"date-time":"2024-11-11T09:30:55Z","timestamp":1731317455000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Takayasu\u2019s arteritis associated with tuberculosis: a retrospective study"],"prefix":"10.1186","volume":"64","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0295-8330","authenticated-orcid":false,"given":"Ana Luisa","family":"Souza Pedreira","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria de Lourdes Castro","family":"de Oliveira Figueiroa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariana Oliveira","family":"Miranda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alisson Regis","family":"de Santana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victor Pereira","family":"Mattos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adriane Sousa","family":"da Paz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Camila Cendon","family":"Duran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mittermayer Barreto","family":"Santiago","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,11,11]]},"reference":[{"key":"424_CR1","first-page":"236","volume":"37","author":"K Sano","year":"1961","unstructured":"Sano K. Obstructive disease of the carotid arteries, with especial reference to angiitis. Med Prog. 1961;37:236.","journal-title":"Med Prog"},{"key":"424_CR2","doi-asserted-by":"publisher","unstructured":"Aggarwal A, Chag M, Sinha N, Naik S. Takayasu\u2019s arteritis: role of Mycobacterium tuberculosis and its 65\u00a0kDa heat shock protein. Int J Cardiol. 1996;55(1):49\u201355. https:\/\/doi.org\/10.1016\/0167-5273(96)02660-5. PMID 8839810.","DOI":"10.1016\/0167-5273(96)02660-5"},{"key":"424_CR3","doi-asserted-by":"publisher","unstructured":"Castillo-Martinez D, Amezcua-Guerra LM. Self-reactivity against stress-induced cell molecules: the missing link between Takayasu\u2019s arteritis and tuberculosis? Med Hypotheses. 2012;78(4):485\u20138. https:\/\/doi.org\/10.1016\/j.mehy.2012.01.012. PMID 22285197.","DOI":"10.1016\/j.mehy.2012.01.012"},{"key":"424_CR4","doi-asserted-by":"publisher","unstructured":"Pedreira ALS, Santiago MB. Association between Takayasu arteritis and latent or active Mycobacterium tuberculosis infection: a systematic review. Clin Rheumatol. 2020;39(4):1019\u201326. https:\/\/doi.org\/10.1007\/s10067-019-04818-5. PMID 31729680.","DOI":"10.1007\/s10067-019-04818-5"},{"issue":"8","key":"424_CR5","doi-asserted-by":"publisher","first-page":"1277","DOI":"10.1007\/s00380-015-0731-8","volume":"31","author":"AY Lim","year":"2016","unstructured":"Lim AY, Lee GY, Jang SY, Gwag HB, Choi SH, Jeon ES, et al. Comparison of clinical characteristics in patients with Takayasu arteritis with and without concomitant tuberculosis. Heart Vessels. 2016;31(8):1277\u201384. https:\/\/doi.org\/10.1007\/s00380-015-0731-8. PMID 26266634.","journal-title":"Heart Vessels"},{"key":"424_CR6","doi-asserted-by":"publisher","unstructured":"Zhang Y, Fan P, Luo F, Zhang HM, Song L, Ma WJ et al. Tuberculosis in Takayasu arteritis: a retrospective study in 1105 Chinese patients. 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Cureus. 2021;13(8):e16927.","journal-title":"Cureus"}],"container-title":["Advances in Rheumatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s42358-024-00424-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s42358-024-00424-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s42358-024-00424-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,13]],"date-time":"2024-11-13T02:10:00Z","timestamp":1731463800000},"score":1,"resource":{"primary":{"URL":"https:\/\/advancesinrheumatology.biomedcentral.com\/articles\/10.1186\/s42358-024-00424-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,11]]},"references-count":16,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["424"],"URL":"https:\/\/doi.org\/10.1186\/s42358-024-00424-5","relation":{},"ISSN":["2523-3106"],"issn-type":[{"value":"2523-3106","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,11,11]]},"assertion":[{"value":"15 February 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 October 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 November 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This study was approved by the Human Research Ethics Committee (Comit\u00ea de \u00c9tica em Pesquisa com Seres Humanos\u2014CEPSH) of Bahiana School of Medicine and Public Health (Escola Bahiana de Medicina e Sa\u00fade P\u00fablica\u2014EBMSP; Certificate of Presentation for Ethical Consideration [Certificado de Apresenta\u00e7\u00e3o de Aprecia\u00e7\u00e3o \u00c9tica\u2014CAAE]: 73383717.3.0000.5544). This study was conducted in accordance with the ethical standards of the 1964 Declaration of Helsinki and its subsequent amendments.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no conflicts of interest.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"84"}}