{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T17:32:18Z","timestamp":1761845538667,"version":"3.37.3"},"reference-count":5,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2022,3,21]],"date-time":"2022-03-21T00:00:00Z","timestamp":1647820800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2022,3,21]],"date-time":"2022-03-21T00:00:00Z","timestamp":1647820800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Neurol. Res. Pract."],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>In this letter we raise several concerns regarding the interesting article by Walter and Kr\u00e4mer about rhomb-encephalitis as a complication two months after the vaccination with an mRNA-based SARS-CoV_2 vaccine. The causal link between the vaccination and encephalitis remained unproven, a SARS-CoV-2 infection, Bickerstaff encephalitis were not excluded, the MRI rather suggests brainstem-encephlaitis than pure rhomb-encephalitis, and the cerebro-spinal fluid was not investigated for cytokines or glial markers. Neurologists are called to make all available effort to convincingly evaluate the etiology and the pathophysiological background of an undetermined condition.<\/jats:p>","DOI":"10.1186\/s42466-022-00178-9","type":"journal-article","created":{"date-parts":[[2022,3,21]],"date-time":"2022-03-21T01:02:37Z","timestamp":1647824557000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Diagnosing SARS-CoV-2 vaccination associated rhombencephalitis requires comprehensive work-up and exclusion of differentials"],"prefix":"10.1186","volume":"4","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2839-7305","authenticated-orcid":false,"given":"Josef","family":"Finsterer","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0694-8674","authenticated-orcid":false,"given":"Fulvio A.","family":"Scorza","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7810-4748","authenticated-orcid":false,"given":"Carla A.","family":"Scorza","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana C.","family":"Fiorini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2022,3,21]]},"reference":[{"issue":"1","key":"178_CR1","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1186\/s42466-021-00156-7","volume":"3","author":"A Walter","year":"2021","unstructured":"Walter, A., & Kraemer, M. (2021). A neurologist\u2019s rhombencephalitis after comirnaty vaccination. A change of perspective. Neurological Research and Practice, 3(1), 56. https:\/\/doi.org\/10.1186\/s42466-021-00156-7","journal-title":"Neurological Research and Practice"},{"key":"178_CR2","doi-asserted-by":"publisher","DOI":"10.1007\/s00115-021-01205-x","author":"F Zuhorn","year":"2021","unstructured":"Zuhorn, F., Graf, T., Klingebiel, R., Sch\u00e4bitz, W. R., & Rogalewski, A. (2021). Seltene Enzephalitis nach Impfung gegen SARS-CoV-2 [Rare encephalitis after vaccination against SARS-CoV-2]. Der Nervenarzt. https:\/\/doi.org\/10.1007\/s00115-021-01205-x","journal-title":"Der Nervenarzt"},{"issue":"10","key":"178_CR3","doi-asserted-by":"publisher","first-page":"1815","DOI":"10.3390\/diagnostics11101815","volume":"11","author":"M Komiazyk","year":"2021","unstructured":"Komiazyk, M., Walory, J., Gawor, J., Ksiazek, I., Gromadka, R., & Baraniak, A. (2021). Case Report of COVID-19 after full vaccination: Viral loads and anti-SARS-CoV-2 antibodies. Diagnostics (Basel), 11(10), 1815. https:\/\/doi.org\/10.3390\/diagnostics11101815","journal-title":"Diagnostics (Basel)"},{"key":"178_CR4","doi-asserted-by":"publisher","DOI":"10.1111\/ane.13550","author":"J Finsterer","year":"2021","unstructured":"Finsterer, J. (2021). Neurological side effects of SARS-CoV-2 vaccinations. Acta Neurologica Scandinavica. https:\/\/doi.org\/10.1111\/ane.13550","journal-title":"Acta Neurologica Scandinavica"},{"issue":"9","key":"178_CR5","doi-asserted-by":"publisher","first-page":"e3019","DOI":"10.1093\/cid\/ciaa1933","volume":"73","author":"A Pilotto","year":"2021","unstructured":"Pilotto, A., Masciocchi, S., Volonghi, I., De Giuli, V., Caprioli, F., Mariotto, S., Ferrari, S., Bozzetti, S., Imarisio, A., Risi, B., Premi, E., Benussi, A., Foc\u00e0, E., Castelli, F., Zanusso, G., Monaco, S., Stefanelli, P., Gasparotti, R., Zekeridou, A., \u2026 Padovani, A. (2021). Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) encephalitis is a cytokine release syndrome: Evidences from cerebrospinal fluid analyses. Clinical Infectious Diseases, 73(9), e3019\u2013e3026. https:\/\/doi.org\/10.1093\/cid\/ciaa1933","journal-title":"Clinical Infectious Diseases"}],"container-title":["Neurological Research and Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s42466-022-00178-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s42466-022-00178-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s42466-022-00178-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,21]],"date-time":"2022-03-21T01:03:17Z","timestamp":1647824597000},"score":1,"resource":{"primary":{"URL":"https:\/\/neurolrespract.biomedcentral.com\/articles\/10.1186\/s42466-022-00178-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3,21]]},"references-count":5,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,12]]}},"alternative-id":["178"],"URL":"https:\/\/doi.org\/10.1186\/s42466-022-00178-9","relation":{},"ISSN":["2524-3489"],"issn-type":[{"type":"electronic","value":"2524-3489"}],"subject":[],"published":{"date-parts":[[2022,3,21]]},"assertion":[{"value":"22 November 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 November 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 March 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"It was in accordance if ethical guidelines. The study was approved by the institutional review board.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}},{"value":"The authors declare that they have no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"10"}}