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The topics were worked on by author-teams based on the current data situation and then coordinated in a first Delphi round by the guideline group.This S1 level guideline (AWMF-registry number 030\u2013100) is based on a systematic pubmed search. Where possible, the following sources were used: pubmed.gov; springer search; google scholar.The core statements were evaluated according to the guidelines of the Oxford Centre for Evidence-based Medicine - Levels of Evidence and from this a strength of recommendation was derived. A strong recommendation corresponds in the formulation to a \u201cshould\u201d, a recommendation to a \u201cshould\u201d and an open recommendation to a \u201ccan\u201d.In a second Delphi round, all recommendations were finally agreed upon by the neurological guidelines group. Based on this expert consensus, the formulation of the core statements was evaluated as strong agreement in the case of >\u200995% of all experts, as agreement in the case of 75\u201395%, as majority agreement in the case of >\u200950\u201375%, and as no agreement in the case of <\u200950%. In this abbreviated guideline we only refer to agreements of 90\u2013100%.The guideline was reviewed by the Guideline Committee of the German Neurological Society and approved by the German Neurological Society. Interdisciplinarity was established.Patient organizations were not involved.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Methological approach"}},{"value":"All participants in the guideline have submitted their declarations of interest (AWMF form for the declaration of interests in the context of guideline projects) to the coordinator or the Editorial Office for Guidelines of the DGN in time and completely filled out. The evaluation of the declarations of interest with regard to thematic relevance to the guideline was carried out by DGN Secretary. The external evaluation of the interests in the overall view was also carried out by AWMF. No conflicts of interest were found, so no consequences, e.g. abstentions, were taken. For reasons of transparency, the interests of the participants and the consequences drawn from them are listed on the respective AWMF guideline website and are also shown in the appendix of the short version.","order":6,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declaration of interest\u00a0<!--Emphasis Type='Bold' removed-->and handling of conflicts of interest"}},{"value":"All funding was provided by the Deutsche Gesellschaft f\u00fcr Neurology DGN (German Neurological Society).This guideline has been produced without any influence or support from industry and is provided by the authors free of charge.","order":7,"name":"Ethics","group":{"name":"EthicsHeading","label":"Funding and financing of the guideline"}}],"article-number":"24"}}