{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T12:32:37Z","timestamp":1777984357557,"version":"3.51.4"},"reference-count":22,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T00:00:00Z","timestamp":1777334400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T00:00:00Z","timestamp":1777334400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Key R&D Program of China","doi-asserted-by":"crossref","award":["2021YFC2401204"],"award-info":[{"award-number":["2021YFC2401204"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2022YFC2503805"],"award-info":[{"award-number":["2022YFC2503805"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Acta Epileptologica"],"published-print":{"date-parts":[[2026,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Piloerection, a physiological response to cold or emotional stimuli, is a rare autonomic manifestation of epileptic seizures. The anatomical correlates and electrophysiological mechanisms of pilomotor seizures remain poorly understood.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a retrospective analysis of 13 patients with pilomotor seizures identified from 8482 individuals monitored at the Epilepsy Center of West China Hospital. Demographics, seizure characteristics, neuroimaging, and neurophysiological findings were analyzed to determine the epileptogenic zones and associated etiologies.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Most (11\/13) of our cases showed temporal lobe origin of seizures, with distinctive ictal encephalogram patterns including rhythmic delta activity. Piloerection was consistently accompanied by other autonomic or psychic symptoms. Most patients responded to anti-seizure medications.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Pilomotor seizures are associated with temporal lobe epilepsy and are frequently associated with specific etiologies such as autoimmune encephalitis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s42494-026-00260-8","type":"journal-article","created":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T11:00:21Z","timestamp":1777374021000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Clinical and electroencephalogram characteristics of pilomotor seizures"],"prefix":"10.1186","volume":"8","author":[{"given":"Zhijun","family":"Le","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bingqian","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hesheng","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yujie","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raowei","family":"Yan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dong","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiani","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xintong","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2026,4,28]]},"reference":[{"issue":"3","key":"260_CR1","doi-asserted-by":"publisher","first-page":"320","DOI":"10.1016\/j.biopsycho.2010.12.012","volume":"86","author":"M Benedek","year":"2011","unstructured":"Benedek M, Kaernbach C. Physiological correlates and emotional specificity of human piloerection. Biol Psychol. 2011;86(3):320\u20139.","journal-title":"Biol Psychol"},{"key":"260_CR2","doi-asserted-by":"publisher","first-page":"e5292","DOI":"10.7717\/peerj.5292","volume":"6","author":"JAJ Heathers","year":"2018","unstructured":"Heathers JAJ, Fayn K, Silvia PJ, Tiliopoulos N, Goodwin MS. The voluntary control of piloerection. PeerJ. 2018;6:e5292.","journal-title":"PeerJ"},{"issue":"6","key":"260_CR3","doi-asserted-by":"publisher","first-page":"1804","DOI":"10.1111\/epi.18338","volume":"66","author":"S Beniczky","year":"2025","unstructured":"Beniczky S, Trinka E, Wirrell E, Abdulla F, Al Baradie R, Alonso Vanegas M, et al. Updated classification of epileptic seizures: position paper of the International League Against Epilepsy. 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This study was approved by the Ethics Committee Biomedical Research, West China Hospital of Sichuan University. (2022[1847]).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"All participants gave consent for publication.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"Author Dong Zhou and Xintong Wu\u00a0are\u00a0the members of the Editorial Board for\n                      Acta Epileptologica\n                      , who were\u00a0not involved in the journal\u2019s review of or decisions related to this manuscript.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"19"}}