{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T08:23:00Z","timestamp":1792743780526,"version":"4.5.0"},"reference-count":31,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,5,7]],"date-time":"2025-05-07T00:00:00Z","timestamp":1746576000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2025,5,7]],"date-time":"2025-05-07T00:00:00Z","timestamp":1746576000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Arthroplasty"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Functional alignment (FA) in total knee arthroplasty (TKA) can achieve soft tissue balance by fine-tuning adjustments of bony resections and component alignment with less soft tissue release. However, joint line orientation relative to the floor in the knee and ankle after TKA is not well studied.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A randomized-controlled trial was performed in 30 patients with robotic-assisted bilateral TKA using FA and mechanical alignment (MA) in the same patient. The outcome measures were as follows: (1) standing radiographic knee and ankle alignment; (2) clinical outcomes at 1, 3 and 6\u00a0months postoperatively (including forgotten joint score (FJS), KOOS, knee range of motion); (3) patient satisfaction score; and (4) soft tissue release.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Postoperative hip-knee-ankle angles between the FA and MA groups were similar (2.4\u00b0 versus 2.4\u00b0,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.952). Knee joint line orientation was significantly more parallel to the floor in the FA group (3.0\u00b0 versus 4.7\u00b0,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.001). There was no significant difference in ankle joint line orientation relative to the floor in the FA and MA groups (91.0\u00b0 versus 92.4\u00b0,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.099 for tibial plafond inclination and 92.5\u00b0 versus 93.2\u00b0,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.564 for talar dome inclination). However, in knees with preoperative varus with apex distal joint line orientation (coronal plane alignment of the knee (CPAK) classification type I), FA significantly achieved a more parallel knee and ankle joint line orientation relative to the floor (3.1\u00b0 versus 5.1\u00b0,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.002 for knee and 91.0\u00b0 versus 93.5\u00b0,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.028 for tibial plafond inclination). FA can obtain a balanced knee with significantly lower posteromedial releases (23.3% versus 76.7%,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.001), with no superficial MCL release needed (0% versus 6.67%,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.01). The FA group achieved significantly higher FJS at 3\u00a0months (53.3 versus 46.0,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.015) and 6\u00a0months (67.8 versus 57.8,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.001) with a higher patient satisfaction score (79.2 versus 84.3,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Functional alignment can control the overall lower limb alignment similarly to mechanical alignment, with a knee joint line more parallel to the floor. Additionally, the ankle joint line was more parallel in knees with CPAK type I. FA can also provide a more balanced knee with less soft tissue release, a higher functional score, and greater patient satisfaction compared to mechanical alignment.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s42836-025-00310-5","type":"journal-article","created":{"date-parts":[[2025,5,6]],"date-time":"2025-05-06T19:02:22Z","timestamp":1746558142000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Comparative effects of mechanical and functional alignment in bilateral robotic total knee arthroplasty: a randomized controlled trial"],"prefix":"10.1186","volume":"7","author":[{"given":"Thakrit","family":"Chompoosang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Utain","family":"Ketkaewsuwan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6405-1136","authenticated-orcid":false,"given":"Patcharavit","family":"Ploynumpon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,5,7]]},"reference":[{"key":"310_CR1","doi-asserted-by":"crossref","unstructured":"Ritter MA. 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All participants gave informed consent to a physician preoperatively. Clinical trial registration number: NCT06259032.Informed consent was obtained from all individual participants included in the study.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval Consent to participate"}},{"value":"The authors affirm that human research participants provided informed consent for publication.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to Publication"}},{"value":"The authors have no relevant financial or non-financial interests to disclose.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing Interests"}}],"article-number":"25"}}