{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T19:42:19Z","timestamp":1757619739482,"version":"3.44.0"},"reference-count":31,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,7,25]],"date-time":"2025-07-25T00:00:00Z","timestamp":1753401600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2025,7,25]],"date-time":"2025-07-25T00:00:00Z","timestamp":1753401600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Knee Surg &amp; Relat Res"],"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:sec>\n            <jats:title>Purpose<\/jats:title>\n            <jats:p>The aim of this study was to compare total perioperative blood loss in patients undergoing total knee arthroplasty (TKA) in different ABO blood types.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods<\/jats:title>\n            <jats:p>This study was approved by the Institutional Review Board of our hospital (IRB No. 1510) on 2 February 2015. A total of 260 knees undergoing unilateral primary cemented cruciate-retaining TKA for knee osteoarthritis were retrospectively registered. Perioperative total blood loss was calculated for each blood types based on the change in hematocrit from pre- to postoperative day 7, preoperative height and weight. Differences in blood loss among the four ABO blood types were assessed. The association between blood type (O versus others) and total blood loss was further evaluated after adjusting for baseline characteristics through inverse probability of treatment weighting (IPTW).<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>The study population was divided based on the ABO blood type: type O, 87; type A, 82; type B, 54; and type AB, 37. The mean total blood loss was 829\u2009\u00b1\u2009370\u00a0ml for type O, 702\u2009\u00b1\u2009384\u00a0ml for type A, 574\u2009\u00b1\u2009361\u00a0ml for type B, and 528\u2009\u00b1\u2009282\u00a0ml for type AB. Patients with blood Type O had significantly higher blood loss than all other blood types. After IPTW adjustment, mean total blood loss remained higher in type O (790\u2009\u00b1\u2009370\u00a0ml) compared to other blood types (613\u2009\u00b1\u2009364\u00a0ml).<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusion<\/jats:title>\n            <jats:p>These findings suggest that blood type O may be associated with increased perioperative blood loss in TKA.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1186\/s43019-025-00284-3","type":"journal-article","created":{"date-parts":[[2025,7,25]],"date-time":"2025-07-25T11:02:28Z","timestamp":1753441348000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Blood type O increased perioperative blood loss in total knee arthroplasty: a propensity score-based inverse probability of treatment weighting matched analysis"],"prefix":"10.1186","volume":"37","author":[{"given":"Yoshihito","family":"Suda","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4067-9233","authenticated-orcid":false,"given":"Naoki","family":"Nakano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshinori","family":"Takashima","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masanori","family":"Tsubosaka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomoyuki","family":"Kamenaga","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuichi","family":"Kuroda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazunari","family":"Ishida","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shinya","family":"Hayashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryosuke","family":"Kuroda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomoyuki","family":"Matsumoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,7,25]]},"reference":[{"key":"284_CR1","doi-asserted-by":"publisher","first-page":"361","DOI":"10.5435\/JAAOS-22-06-361","volume":"22","author":"BR Levine","year":"2014","unstructured":"Levine BR, Haughom B, Strong B, Hellman M, Frank RM (2014) Blood management strategies for total knee arthroplasty. J Am Acad Orthop Surg 22:361\u2013371","journal-title":"J Am Acad Orthop Surg"},{"key":"284_CR2","doi-asserted-by":"publisher","first-page":"227","DOI":"10.1016\/j.jor.2021.03.004","volume":"24","author":"RL Donovan","year":"2021","unstructured":"Donovan RL, Lostis E, Jones I, Whitehouse MR (2021) Estimation of blood volume and blood loss in primary total hip and knee replacement: an analysis of formulae for perioperative calculations and their ability to predict length of stay and blood transfusion requirements. J Orthop 24:227\u2013232","journal-title":"J Orthop"},{"key":"284_CR3","doi-asserted-by":"publisher","first-page":"2114","DOI":"10.3390\/jcm11082114","volume":"11","author":"R Papalia","year":"2022","unstructured":"Papalia R, Torre G, Alifano AM, Albo E, Papalia GF, Bravi M, De Vincentis A, Zappal\u00e0 E, Zampogna B, Denaro V (2022) Length of hospital stay after total knee arthroplasty: a correlation study on 1200 patients. J Clin Med 11:2114","journal-title":"J Clin Med"},{"key":"284_CR4","doi-asserted-by":"publisher","first-page":"771","DOI":"10.1185\/03007995.2016.1142431","volume":"32","author":"X Fu","year":"2016","unstructured":"Fu X, Tian P, Li ZJ, Sun XL, Ma XL (2016) Postoperative leg position following total knee arthroplasty influences blood loss and range of motion: a meta-analysis of randomized controlled trials. Curr Med Res Opin 32:771\u2013778","journal-title":"Curr Med Res Opin"},{"key":"284_CR5","doi-asserted-by":"publisher","first-page":"234","DOI":"10.1016\/j.bja.2022.11.003","volume":"130","author":"CJ DeFrancesco","year":"2023","unstructured":"DeFrancesco CJ, Reichel JF, Gbaje E, Popovic M, Freeman C, Wong M, DeMeo D, Liu J, Gonzalez Della Valle A, Ranawat A, Cross M, Sculco PK, Haskins S, Kim D, Maalouf D, Kirksey M, Jules-Elysee K, Soffin EM, Kumar K, Beathe J, Figgie M, Inglis A Jr, Garvin S, Alexiades M, DelPizzo K, Russell LA, Sideris A, Saleh J, Zhong H, Memtsoudis SG (2023) Effectiveness of oral versus intravenous tranexamic acid in primary total hip and knee arthroplasty: a randomised, non-inferiority trial. Br J Anaesth 130:234\u201341","journal-title":"Br J Anaesth"},{"key":"284_CR6","doi-asserted-by":"publisher","first-page":"1312","DOI":"10.1111\/jcpt.13725","volume":"47","author":"T Ling","year":"2022","unstructured":"Ling T, Zhang L, Huang L (2022) The efficacy and safety of combined administration of intravenous and intra-articular tranexamic acid in total knee arthroplasty: an update meta-analysis. J Clin Pharm Ther 47:1312\u20131321","journal-title":"J Clin Pharm Ther"},{"key":"284_CR7","doi-asserted-by":"publisher","first-page":"1785","DOI":"10.1007\/s00402-019-03271-y","volume":"139","author":"Z Dong","year":"2019","unstructured":"Dong Z, Han L, Song Y, Qi J, Wang F (2019) Hemostatic techniques to reduce blood transfusion after primary TKA: a meta-analysis and systematic review. Arch Orthop Trauma Surg 139:1785\u20131796","journal-title":"Arch Orthop Trauma Surg"},{"key":"284_CR8","first-page":"419","volume":"31","author":"A Levent","year":"2020","unstructured":"Levent A, K\u00f6se \u00d6, Linke P, Gehrke T, \u00c7\u0131tak M (2020) Does tourniquet use decrease blood loss following primary total knee arthroplasty in Jehovah\u2019s Witness patients? Jt Dis Relat Surg 31:419\u2013425","journal-title":"Jt Dis Relat Surg"},{"key":"284_CR9","doi-asserted-by":"publisher","first-page":"e1343","DOI":"10.5435\/JAAOS-D-20-00796","volume":"29","author":"V Tirumala","year":"2021","unstructured":"Tirumala V, Klemt C, Oganseyan R, Walker P, Padmanabha A, Kwon YM (2021) Outcomes of tourniquet-less revision total knee arthroplasty: a matched cohort analysis. J Am Acad Orthop Surg 29:e1343\u2013e1352","journal-title":"J Am Acad Orthop Surg"},{"key":"284_CR10","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1016\/S0968-0160(00)00047-8","volume":"7","author":"KR Sehat","year":"2000","unstructured":"Sehat KR, Evans R, Newman JH (2000) How much blood is really lost in total knee arthroplasty?. Correct blood loss management should take hidden loss into account. Knee 7:151\u20135","journal-title":"Knee"},{"key":"284_CR11","doi-asserted-by":"publisher","first-page":"532","DOI":"10.1016\/j.wneu.2016.10.065","volume":"97","author":"D Dubinski","year":"2017","unstructured":"Dubinski D, Won SY, Konczalla J, Mersmann J, Geisen C, Herrmann E, Seifert V, Senft C (2017) The role of ABO blood group in cerebral vasospasm, associated intracranial hemorrhage, and delayed cerebral ischemia in 470 patients with subarachnoid hemorrhage. World Neurosurg 97:532\u2013537","journal-title":"World Neurosurg"},{"key":"284_CR12","doi-asserted-by":"publisher","first-page":"320","DOI":"10.1002\/ijc.34533","volume":"153","author":"H Cui","year":"2023","unstructured":"Cui H, Qu Y, Zhang L, Zhang W, Yan P, Yang C, Zhang M, Bai Y, Tang M, Wang Y, Chen L, Xiao C, Zou Y, Liu Y, Zhang L, Yang Y, Yao Y, Li J, Liu Z, Yang C, Jiang X, Zhang B (2023) Epidemiological and genetic evidence for the relationship between ABO blood group and human cancer. Int J Cancer 153:320\u2013330","journal-title":"Int J Cancer"},{"key":"284_CR13","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1186\/s12881-020-0975-8","volume":"21","author":"Y Li","year":"2020","unstructured":"Li Y, Liu L, Huang Y, Zheng H, Li L (2020) Association of ABO polymorphisms and pancreatic cancer\/cardiocerebrovascular disease: a meta-analysis. BMC Med Genet 21:41","journal-title":"BMC Med Genet"},{"key":"284_CR14","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2019-034114","volume":"10","author":"W Jing","year":"2020","unstructured":"Jing W, Zhao S, Liu J, Liu M (2020) ABO blood groups and hepatitis B virus infection: a systematic review and meta-analysis. BMJ Open 10:e034114","journal-title":"BMJ Open"},{"key":"284_CR15","doi-asserted-by":"publisher","first-page":"535","DOI":"10.1055\/s-0032-1315758","volume":"38","author":"F Dentali","year":"2012","unstructured":"Dentali F, Sironi AP, Ageno W, Turato S, Bonfanti C, Frattini F, Crestani S, Franchini M (2012) Non-O blood type is the commonest genetic risk factor for VTE: results from a meta-analysis of the literature. Semin Thromb Hemost 38:535\u2013548","journal-title":"Semin Thromb Hemost"},{"key":"284_CR16","doi-asserted-by":"publisher","first-page":"100","DOI":"10.1186\/s13054-018-2022-0","volume":"22","author":"W Takayama","year":"2018","unstructured":"Takayama W, Endo A, Koguchi H, Sugimoto M, Murata K, Otomo Y (2018) The impact of blood type O on mortality of severe trauma patients: a retrospective observational study. Crit Care 22:100","journal-title":"Crit Care"},{"key":"284_CR17","doi-asserted-by":"publisher","first-page":"2311","DOI":"10.1016\/j.jstrokecerebrovasdis.2019.05.022","volume":"28","author":"Q He","year":"2019","unstructured":"He Q, Zhou Y, Wang F, Li B, Cheng Y, Xie ZY (2019) Blood type O predicts hematoma expansion in patients with intracerebral hemorrhage. J Stroke Cerebrovasc Dis 28:2311\u20132317","journal-title":"J Stroke Cerebrovasc Dis"},{"key":"284_CR18","doi-asserted-by":"publisher","first-page":"277","DOI":"10.1097\/00000542-198303000-00016","volume":"58","author":"JB Gross","year":"1983","unstructured":"Gross JB (1983) Estimating allowable blood loss: corrected for dilution. Anesthesiology 58:277\u2013280","journal-title":"Anesthesiology"},{"key":"284_CR19","first-page":"224","volume":"51","author":"SB Nadler","year":"1962","unstructured":"Nadler SB, Hidalgo JH, Bloch T (1962) Prediction of blood volume in normal human adults. Surgery 51:224\u2013232","journal-title":"Surgery"},{"key":"284_CR20","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1186\/s12891-024-07331-2","volume":"25","author":"X Li","year":"2024","unstructured":"Li X, Xie H, Liu S, Wang J, Shi Z, Yao Q, Yang Q, Li Q, Bao L (2024) Analysis of the incidence and risk factors of blood transfusion in total knee revision: a retrospective nationwide inpatient sample database study. BMC Musculoskelet Disord 25:225","journal-title":"BMC Musculoskelet Disord"},{"key":"284_CR21","first-page":"e22","volume":"8","author":"I Shichman","year":"2023","unstructured":"Shichman I, Roof M, Askew N, Nherera L, Rozell JC, Seyler TM, Schwarzkopf R (2023) Projections and epidemiology of primary hip and knee arthroplasty in medicare patients to 2040\u20132060. JB JS Open Access. 8:e22","journal-title":"JB JS Open Access."},{"key":"284_CR22","doi-asserted-by":"publisher","first-page":"432","DOI":"10.1016\/j.jclinane.2014.01.019","volume":"26","author":"R Komatsu","year":"2014","unstructured":"Komatsu R, Dalton JE, Ghobrial M, Fu AY, Lee JH, Egan C, Sessler DI, Kasuya Y, Turan A (2014) Blood Type O is not associated with increased blood loss in extensive spine surgery. J Clin Anesth 26:432\u2013437","journal-title":"J Clin Anesth"},{"key":"284_CR23","doi-asserted-by":"publisher","first-page":"1103","DOI":"10.1160\/th14-05-0457","volume":"112","author":"M Franchini","year":"2014","unstructured":"Franchini M, Mannucci PM (2014) ABO blood group and thrombotic vascular disease. Thromb Haemost 112:1103\u20131109","journal-title":"Thromb Haemost"},{"key":"284_CR24","first-page":"491","volume":"11","author":"GM Liumbruno","year":"2013","unstructured":"Liumbruno GM, Franchini M (2013) Beyond immunohaematology: the role of the ABO blood group in human diseases. Blood Transfus 11:491\u2013499","journal-title":"Blood Transfus"},{"key":"284_CR25","doi-asserted-by":"publisher","first-page":"3540","DOI":"10.1182\/blood-2007-11-122945","volume":"111","author":"L Gallinaro","year":"2008","unstructured":"Gallinaro L, Cattini MG, Sztukowska M, Padrini R, Sartorello F, Pontara E, Bertomoro A, Daidone V, Pagnan A, Casonato A (2008) A shorter von Willebrand factor survival in O blood group subjects explains how ABO determinants influence plasma von Willebrand factor. Blood 111:3540\u20133545","journal-title":"Blood"},{"key":"284_CR26","doi-asserted-by":"publisher","first-page":"2864","DOI":"10.1182\/blood.2020005843","volume":"136","author":"SE Ward","year":"2020","unstructured":"Ward SE, O\u2019Sullivan JM, O\u2019Donnell JS (2020) The relationship between ABO blood group, von Willebrand factor, and primary hemostasis. Blood 136:2864\u20132874","journal-title":"Blood"},{"key":"284_CR27","doi-asserted-by":"publisher","first-page":"1836","DOI":"10.1111\/j.1537-2995.2006.00975.x","volume":"46","author":"PV Jenkins","year":"2006","unstructured":"Jenkins PV, O\u2019Donnell JS (2006) ABO blood group determines plasma von Willebrand factor levels: a biologic function after all? Transfusion 46:1836\u20131844","journal-title":"Transfusion"},{"key":"284_CR28","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1046\/j.1537-2995.2001.41010056.x","volume":"41","author":"A Moeller","year":"2001","unstructured":"Moeller A, Weippert-Kretschmer M, Prinz H, Kretschmer V (2001) Influence of ABO blood groups on primary hemostasis. Transfusion 41:56\u201360","journal-title":"Transfusion"},{"key":"284_CR29","doi-asserted-by":"publisher","first-page":"895","DOI":"10.1182\/blood.V70.4.895.895","volume":"70","author":"ZM Ruggeri","year":"1987","unstructured":"Ruggeri ZM, Zimmerman TS (1987) von Willebrand factor and von Willebrand disease. Blood 70:895\u2013904","journal-title":"Blood"},{"key":"284_CR30","doi-asserted-by":"publisher","first-page":"72","DOI":"10.1055\/s-0032-1329550","volume":"39","author":"F Dentali","year":"2013","unstructured":"Dentali F, Sironi AP, Ageno W, Bonfanti C, Crestani S, Frattini F, Steidl L, Franchini M (2013) Relationship between ABO blood group and hemorrhage: a systematic literature review and meta-analysis. Semin Thromb Hemost 39:72\u201382","journal-title":"Semin Thromb Hemost"},{"key":"284_CR31","doi-asserted-by":"publisher","first-page":"1977","DOI":"10.4103\/0366-6999.160620","volume":"128","author":"ZY Chen","year":"2015","unstructured":"Chen ZY, Wu HZ, Zhu P, Feng XB (2015) Postoperative changes in hemoglobin and hematocrit in patients undergoing primary total hip and knee arthroplasty. Chin Med J (Engl) 128:1977\u20131979","journal-title":"Chin Med J (Engl)"}],"container-title":["Knee Surgery &amp; Related Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s43019-025-00284-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s43019-025-00284-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s43019-025-00284-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,7]],"date-time":"2025-09-07T23:45:37Z","timestamp":1757288737000},"score":1,"resource":{"primary":{"URL":"https:\/\/kneesurgrelatres.biomedcentral.com\/articles\/10.1186\/s43019-025-00284-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,25]]},"references-count":31,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["284"],"URL":"https:\/\/doi.org\/10.1186\/s43019-025-00284-3","relation":{},"ISSN":["2234-2451"],"issn-type":[{"type":"electronic","value":"2234-2451"}],"subject":[],"published":{"date-parts":[[2025,7,25]]},"assertion":[{"value":"8 May 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 July 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"25 July 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This study was approved by the Institutional Review Board (IRB no. 1510) and was conducted in accordance with the Declaration of Helsinki. The requirement for informed consent from each patient was waived because the design of the study was retrospective in nature and because of the use of anonymized patient and hospital data.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"All authors declare that they have no conflicts of interest.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"32"}}