{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T18:43:16Z","timestamp":1791916996575,"version":"4.3.4"},"reference-count":8,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,7,2]],"date-time":"2025-07-02T00:00:00Z","timestamp":1751414400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2025,7,2]],"date-time":"2025-07-02T00:00:00Z","timestamp":1751414400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Egypt Heart J"],"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:sec>\n            <jats:title>Background<\/jats:title>\n            <jats:p>Situs inversus with dextrocardia (SI-DC) is rarely associated with congenital heart defects. Traditionally, ventricular septal defect (VSD) in such patients has been managed surgically. Percutaneous VSD device closure in SI-DC, albeit a suitable alternative, has been seldom reported. The present report describes the unique challenges of mirror-image cardiac anatomy and suggests technical modifications for successful percutaneous closure.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Case summary<\/jats:title>\n            <jats:p>A 4-year-old boy, previously diagnosed with SI-DC and a moderate-size perimembranous VSD, presented with a history of poor weight gain and dyspnea. A 2D echocardiogram indicated that the septal defect was suitable for device closure. The procedure was adapted to account for the altered cardiac anatomy by adjusting the fluoroscopic angles and wire-torquing maneuvers. A Konar-multifunction occluder device MFO\u00ae 7-5mm was successfully deployed via retrograde approach without complications utilizing hemodynamic and echocardiographic guidance. No excess contrast volume or fluoroscopic radiation dose was used during the procedure due to meticulous pre-procedure planning.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusion<\/jats:title>\n            <jats:p>VSD device closure in atypical scenarios like SI-DC is both safe and feasible with thorough pre-procedure planning tailored to the \"mirror image\" cardiac anatomy.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1186\/s43044-025-00665-9","type":"journal-article","created":{"date-parts":[[2025,7,2]],"date-time":"2025-07-02T08:57:30Z","timestamp":1751446650000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["VSD device closure in situs inversus with dextrocardia: technical challenges and solutions: a case report"],"prefix":"10.1186","volume":"77","author":[{"given":"Abhimanyu","family":"Uppal","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bhushan","family":"Shah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rambabu","family":"Sharma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashok","family":"Garg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,7,2]]},"reference":[{"issue":"10","key":"665_CR1","doi-asserted-by":"publisher","first-page":"1565","DOI":"10.1093\/hmg\/7.10.1565","volume":"7","author":"B Casey","year":"1998","unstructured":"Casey B (1998) Two rights make a wrong: human left\u2013right malformations. Hum Mol Genet 7(10):1565\u20131571. https:\/\/doi.org\/10.1093\/hmg\/7.10.1565","journal-title":"Hum Mol Genet"},{"issue":"4","key":"665_CR2","doi-asserted-by":"publisher","first-page":"279","DOI":"10.4103\/JASI.JASI_69_19","volume":"68","author":"V Kumar","year":"2019","unstructured":"Kumar V, Singh RS, Mishra AK (2019) Spectrum of congenital cardiac malformations in dextrocardia: a single institute study. J Anat Soc India 68(4):279\u2013284","journal-title":"J Anat Soc India"},{"issue":"5","key":"665_CR3","doi-asserted-by":"publisher","first-page":"558","DOI":"10.1016\/s0003-4975(10)62129-7","volume":"44","author":"LS Fox","year":"1987","unstructured":"Fox LS (1987) An easy and safe technique for ventricular septal defect closure in hearts with atrioventricular discordant connection and dextrocardia. Ann Thorac Surg 44(5):558\u2013559. https:\/\/doi.org\/10.1016\/s0003-4975(10)62129-7","journal-title":"Ann Thorac Surg"},{"key":"665_CR4","doi-asserted-by":"publisher","first-page":"267","DOI":"10.1016\/0002-9149(65)90465-0","volume":"15","author":"EB Kay","year":"1965","unstructured":"Kay EB, Rodriguez P, Zimmerman HA (1965) Surgery for ventricular septal defect in dextroversion through a left ventriculotomy. Am J Cardiol 15:267\u2013273. https:\/\/doi.org\/10.1016\/0002-9149(65)90465-0","journal-title":"Am J Cardiol"},{"key":"665_CR5","doi-asserted-by":"publisher","DOI":"10.32388\/j1zzl5","author":"A Darbari","year":"2024","unstructured":"Darbari A, Rawat SS, Kumar B (2024) A case report of situs inversus totalis with ventricular septal defect: flipped physiology. Qeios. https:\/\/doi.org\/10.32388\/j1zzl5","journal-title":"Qeios"},{"key":"665_CR6","doi-asserted-by":"publisher","first-page":"9801768","DOI":"10.36106\/paripex","volume":"9","author":"R Rai","year":"2020","unstructured":"Rai R, Waghmare N (2020) VSD device closure in a case of dextrocardia. PARIPEX Indian J Res 9:9801768. https:\/\/doi.org\/10.36106\/paripex","journal-title":"PARIPEX Indian J Res"},{"issue":"1","key":"665_CR7","doi-asserted-by":"publisher","first-page":"32","DOI":"10.4103\/JICC.JICC_21_20","volume":"11","author":"M Roy","year":"2021","unstructured":"Roy M, Gangopadhyay D, Patel P (2021) Working in the mirror: a case series on interventions in children having dextrocardia with congenital heart disease. J Indian Coll Cardiol 11(1):32\u201336","journal-title":"J Indian Coll Cardiol"},{"issue":"1","key":"665_CR8","doi-asserted-by":"publisher","first-page":"15","DOI":"10.5334\/gh.1106","volume":"17","author":"RB Kuswiyanto","year":"2022","unstructured":"Kuswiyanto RB, Gunawijaya E, Djer MM, Noormanto RMA et al (2022) Transcatheter closure of perimembranous ventricular septal defect using the Lifetech Konar-Multi Functional Occluder: early to midterm results of the Indonesian multicenter study. Glob Heart 17(1):15. https:\/\/doi.org\/10.5334\/gh.1106","journal-title":"Glob Heart"}],"container-title":["The Egyptian Heart Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s43044-025-00665-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s43044-025-00665-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s43044-025-00665-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,2]],"date-time":"2025-07-02T08:57:30Z","timestamp":1751446650000},"score":1,"resource":{"primary":{"URL":"https:\/\/tehj.springeropen.com\/articles\/10.1186\/s43044-025-00665-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,2]]},"references-count":8,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["665"],"URL":"https:\/\/doi.org\/10.1186\/s43044-025-00665-9","relation":{},"ISSN":["2090-911X"],"issn-type":[{"value":"2090-911X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7,2]]},"assertion":[{"value":"5 April 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 June 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 July 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Obtained from parents.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"A written informed consent for publication of this case report that includes patient details, images, and videos was obtained from parents according to institutional protocol.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interest"}}],"article-number":"69"}}