{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,16]],"date-time":"2025-09-16T16:39:58Z","timestamp":1758040798623,"version":"3.44.0"},"reference-count":9,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T00:00:00Z","timestamp":1757548800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T00:00:00Z","timestamp":1757548800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Egypt Heart J"],"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:sec>\n            <jats:title>Background<\/jats:title>\n            <jats:p>Cardiac tamponade is an extreme cardiological emergency, fatal in the absence of rapid intervention. This case report highlights a noteworthy and rare correlation between post-polycythemia vera myelofibrosis and extramedullary hematopoiesis affecting the pericardium, leading to tamponade or pericardial effusion.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Case presentation<\/jats:title>\n            <jats:p>A 69-year-old female with a history of polycythemia vera presented with worsening dyspnea, fever, and altered condition. Examination revealed low blood pressure, tachycardia, jugular vein distention, and muffled heart sounds, leading to a diagnosis of cardiac tamponade due to a large pericardial effusion. Emergency pericardiocentesis was performed, revealing serosanguineous fluid with signs of clonally proliferative hematopoietic cells, indicating possible progression to myelofibrosis. Bone marrow biopsy confirmed post-polycythemia vera myelofibrosis. The patient\u2019s condition improved, and she was referred back to her hematologist for further management.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusion<\/jats:title>\n            <jats:p>Increased awareness may improve early diagnosis and treatment, ultimately enhancing patient outcomes.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1186\/s43044-025-00680-w","type":"journal-article","created":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T09:39:20Z","timestamp":1757583560000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A rare case of extramedullary hematopoiesis: when the pericardium produces blood cells"],"prefix":"10.1186","volume":"77","author":[{"given":"SALAH-EDDINE","family":"HAYAR","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"MEHDI","family":"TAMIR","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"MOHAMED","family":"KHALDI","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"MAHA","family":"BOUZIANE","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"MERYEM","family":"HABOUB","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"SALIM","family":"AROUS","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"MOHAMED GHALI","family":"BENNOUNA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"ABDENASSER","family":"DRIGHIL","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"RACHIDA","family":"HABBAL","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"ABDERRAHMANE","family":"MELLOUKI","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,9,11]]},"reference":[{"issue":"42","key":"680_CR1","doi-asserted-by":"publisher","first-page":"2921","DOI":"10.1093\/eurheartj\/ehv318","volume":"36","author":"Y Adler","year":"2015","unstructured":"Adler Y, Charron P, Imazio M, Badano L, Bar\u00f3n-Esquivias G, Bogaert J et al (2015) 2015 ESC guidelines for the diagnosis and management of pericardial diseases: the task force for the diagnosis and management of pericardial diseases of the european society of cardiology (ESC) endorsed by: the european association for cardio-thoracic surgery (EACTS). 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AJR Am J Roentgenol 179(5):1239\u20131243","journal-title":"AJR Am J Roentgenol"},{"issue":"10","key":"680_CR5","doi-asserted-by":"publisher","first-page":"1223","DOI":"10.4065\/78.10.1223","volume":"78","author":"CA Koch","year":"2003","unstructured":"Koch CA, Li CY, Mesa RA, Tefferi A (2003) Nonhepatosplenic extramedullary hematopoiesis: associated diseases, pathology, clinical course, and treatment. Mayo Clin Proc 78(10):1223\u20131233","journal-title":"Mayo Clin Proc"},{"issue":"3","key":"680_CR6","doi-asserted-by":"publisher","first-page":"255","DOI":"10.1053\/j.sult.2013.12.001","volume":"35","author":"E Orphanidou-Vlachou","year":"2014","unstructured":"Orphanidou-Vlachou E, Tziakouri-Shiakalli C, Georgiades CS (2014) Extramedullary hemopoiesis. Semin Ultrasound CT MR 35(3):255\u2013262","journal-title":"Semin Ultrasound CT MR"},{"issue":"5","key":"680_CR7","doi-asserted-by":"publisher","first-page":"371","DOI":"10.1016\/j.carpath.2016.05.007","volume":"25","author":"NR Mahadevan","year":"2016","unstructured":"Mahadevan NR, Morgan EA, Mitchell RN (2016) Case report and literature review: cardiac tamponade as a complication of pericardial extramedullary hematopoiesis. Cardiovasc Pathol 25(5):371\u2013374","journal-title":"Cardiovasc Pathol"},{"issue":"9","key":"680_CR8","doi-asserted-by":"publisher","first-page":"E544","DOI":"10.1002\/ajh.24800","volume":"92","author":"S Lavu","year":"2017","unstructured":"Lavu S, Tefferi A (2017) Cardiac tamponade in myelofibrosis: a mayo clinic series of nine consecutive cases. 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A copy of the consent form is available for review by the Editor of this journal.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}}],"article-number":"86"}}