{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T23:19:41Z","timestamp":1788477581478,"version":"build-2803163510"},"reference-count":59,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T00:00:00Z","timestamp":1788480000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T00:00:00Z","timestamp":1788480000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Key R&D Program of China","doi-asserted-by":"crossref","award":["2022YFF1003104"],"award-info":[{"award-number":["2022YFF1003104"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100012166","name":"National Key R&D Program of China","doi-asserted-by":"crossref","award":["2021YFD1200205"],"award-info":[{"award-number":["2021YFD1200205"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["32172615, 32573066"],"award-info":[{"award-number":["32172615, 32573066"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["32372744"],"award-info":[{"award-number":["32372744"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"name":"'JBGS' Project of Seed Industry Revitalization in Jiangsu Province","award":["JBGS (2021)020"],"award-info":[{"award-number":["JBGS (2021)020"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Mol Horticulture"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Flower size is a key ornamental trait in roses (\n                    <jats:italic>Rosa<\/jats:italic>\n                    spp.), determined by coordinated regulation of cell proliferation and expansion. Although jasmonic acid (JA) influences plant growth, its role in flower size control remains unclear. Here, we showed that methyl jasmonate (MeJA) treatment reduces flower size in\n                    <jats:italic>Rosa chinensis<\/jats:italic>\n                    , accompanied by elevated expression of the JA-responsive transcription factor\n                    <jats:italic>RcMYC2<\/jats:italic>\n                    . Silencing\n                    <jats:italic>RcMYC2<\/jats:italic>\n                    resulted in larger flowers due to enhanced petal cell expansion and upregulation of cell expansion-related genes. Mechanistically, RcMYC2 directly bound to the promoter of the expansin gene\n                    <jats:italic>RcEXPA8<\/jats:italic>\n                    and repressed its transcription via its interaction with the Mediator subunit RcMED25. Consistently, MeJA failed to reduce flower size in\n                    <jats:italic>RcMED25<\/jats:italic>\n                    -silenced plants. Upon JA signal activation, RcMYC2 recruited RcMED25 and the histone deacetylase RcHDA8 to the\n                    <jats:italic>RcEXPA8<\/jats:italic>\n                    promoter, leading to transcriptional repression via histone deacetylation and restriction of petal cell expansion. These findings demonstrate that histone deacetylation links JA signaling to flower size control, providing new insights into hormone-mediated regulation of organ growth in ornamental plants.\n                  <\/jats:p>","DOI":"10.1186\/s43897-026-00261-8","type":"journal-article","created":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T23:02:16Z","timestamp":1788476536000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Histone deacetylation links jasmonic acid signaling to flower size control in rose"],"prefix":"10.1186","volume":"6","author":[{"given":"Yufei","family":"Chang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yali","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin","family":"Jin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunguo","family":"Fan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hmmam","family":"Zarif","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guozhen","family":"Yuan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rui","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongchi","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingjing","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Changquan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinyi","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,9,4]]},"reference":[{"key":"261_CR1","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1016\/j.pbi.2006.11.002","volume":"10","author":"E Anastasiou","year":"2007","unstructured":"Anastasiou E, Lenhard M. Growing up to one\u2019s standard. Curr Opin Plant Biol. 2007;10:63\u20139. https:\/\/doi.org\/10.1016\/j.pbi.2006.11.002.","journal-title":"Curr Opin Plant Biol"},{"key":"261_CR2","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1038\/s41438-021-00464-8","volume":"8","author":"M Bai","year":"2021","unstructured":"Bai M, Liu J, Fan C, Chen Y, Chen H, Lu J, et al. KSN heterozygosity is associated with continuous flowering of Rosa rugosa purple branch. Hortic Res. 2021;8:26. https:\/\/doi.org\/10.1038\/s41438-021-00464-8.","journal-title":"Hortic Res"},{"key":"261_CR3","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1105\/tpc.110.079079","volume":"23","author":"I Bartrina","year":"2011","unstructured":"Bartrina I, Otto E, Strnad M, Werner T, Schm\u00fclling T. Cytokinin regulates the activity of reproductive meristems, flower organ size, ovule formation, and thus seed yield in Arabidopsis thaliana. Plant Cell. 2011;23:69\u201380. https:\/\/doi.org\/10.1105\/tpc.110.079079.","journal-title":"Plant Cell"},{"key":"261_CR4","doi-asserted-by":"publisher","first-page":"142","DOI":"10.1016\/S0959-437X(02)00279-4","volume":"12","author":"SL Berger","year":"2002","unstructured":"Berger SL. Histone modifications in transcriptional regulation. Curr Opin Genet Dev. 2002;12:142\u20138. https:\/\/doi.org\/10.1016\/S0959-437X(02)00279-4.","journal-title":"Curr Opin Genet Dev"},{"key":"261_CR5","doi-asserted-by":"publisher","first-page":"106","DOI":"10.1105\/tpc.19.00004","volume":"31","author":"E Breeze","year":"2019","unstructured":"Breeze E. Master MYCs: MYC2, the Jasmonate signaling \u201cMaster Switch.\u201d Plant Cell. 2019;31:106\u201327. https:\/\/doi.org\/10.1105\/tpc.19.00004.","journal-title":"Plant Cell"},{"key":"261_CR6","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1016\/S0070-2153(10)91007-7","volume":"91","author":"H Breuninger","year":"2010","unstructured":"Breuninger H, Lenhard M. Control of tissue and organ growth in plants. Curr Top Dev Biol. 2010;91:185\u2013220. https:\/\/doi.org\/10.1016\/S0070-2153(10)91007-7.","journal-title":"Curr Top Dev Biol"},{"key":"261_CR7","doi-asserted-by":"publisher","first-page":"1070","DOI":"10.1111\/j.1365-313X.2009.04023.x","volume":"60","author":"F Brioudes","year":"2009","unstructured":"Brioudes F, Joly C, Sz\u00e9csi J, Varaud E, Leroux J, Bellvert F, et al. Jasmonate controls late development stages of petal growth in Arabidopsis thaliana. Plant J. 2009;60:1070\u201380. https:\/\/doi.org\/10.1111\/j.1365-313X.2009.04023.x.","journal-title":"Plant J"},{"key":"261_CR8","doi-asserted-by":"publisher","first-page":"541","DOI":"10.1104\/pp.112.202697","volume":"160","author":"V \u00c7evik","year":"2012","unstructured":"\u00c7evik V, Kidd BN, Zhang P, Hill C, Kiddle S, Denby KJ, et al. MEDIATOR25 acts as an integrative hub for the regulation of jasmonate-responsive gene expression in Arabidopsis thaliana. Plant Physiol. 2012;160:541\u201355. https:\/\/doi.org\/10.1104\/pp.112.202697.","journal-title":"Plant Physiol"},{"key":"261_CR9","doi-asserted-by":"publisher","first-page":"3732","DOI":"10.1105\/tpc.109.066845","volume":"21","author":"JB Charron","year":"2009","unstructured":"Charron JB, He H, Elling AA, Deng XW. Dynamic landscapes of four histone modifications during deetiolation in Arabidopsis thaliana. Plant Cell. 2009;21:3732\u201348. https:\/\/doi.org\/10.1105\/tpc.109.066845.","journal-title":"Plant Cell"},{"key":"261_CR10","doi-asserted-by":"publisher","first-page":"1352","DOI":"10.1007\/s11105-025-01553-x","volume":"43","author":"N Chakraborty","year":"2025","unstructured":"Chakraborty N, Basu R, Ojha M, Chattopadhyay S. MYC2-mediated regulation of FLC controls photomorphogenic growth and flowering time. Plant Mol Biol Rep. 2025;43:1352\u201368. https:\/\/doi.org\/10.1007\/s11105-025-01553-x.","journal-title":"Plant Mol Biol Rep"},{"key":"261_CR11","doi-asserted-by":"publisher","first-page":"4489","DOI":"10.1093\/jxb\/erad173","volume":"74","author":"C Chen","year":"2023","unstructured":"Chen C, Hussain N, Ma Y, Zuo L, Jiang Y, Sun X, et al. The ARF2\u2013MYB6 module mediates auxin-regulated petal expansion in rose. J Exp Bot. 2023;74:4489\u2013502. https:\/\/doi.org\/10.1093\/jxb\/erad173.","journal-title":"J Exp Bot"},{"key":"261_CR12","doi-asserted-by":"publisher","first-page":"2898","DOI":"10.1105\/tpc.112.098277","volume":"24","author":"R Chen","year":"2012","unstructured":"Chen R, Jiang H, Li L, Zhai Q, Qi L, Zhou W, et al. The Arabidopsis mediator subunit MED25 differentially regulates jasmonate and abscisic acid signaling through interacting with the MYC2 and ABI5 transcription factors. Plant Cell. 2012;24:2898\u2013916. https:\/\/doi.org\/10.1105\/tpc.112.098277.","journal-title":"Plant Cell"},{"key":"261_CR13","doi-asserted-by":"publisher","unstructured":"Chen Y, Lu J, Wang W, Fan C, Yuan G, Sun J, et al. Rose long noncoding RNA lncWD83 promotes flowering by modulating ubiquitination of the floral repressor RcMYC2L. Plant Physiol. 2023;193(4):2573-91. https:\/\/doi.org\/10.1093\/plphys\/kiad502.","DOI":"10.1093\/plphys\/kiad502"},{"key":"261_CR14","doi-asserted-by":"publisher","first-page":"321","DOI":"10.1038\/35030000","volume":"407","author":"DJ Cosgrove","year":"2000","unstructured":"Cosgrove DJ. Loosening of plant cell walls by expansins. Nature. 2000;407:321\u20136. https:\/\/doi.org\/10.1038\/35030000.","journal-title":"Nature"},{"key":"261_CR15","doi-asserted-by":"publisher","first-page":"850","DOI":"10.1038\/nrm1746","volume":"6","author":"DJ Cosgrove","year":"2005","unstructured":"Cosgrove DJ. Growth of the plant cell wall. Nat Rev Mol Cell Biol. 2005;6:850\u201361. https:\/\/doi.org\/10.1038\/nrm1746.","journal-title":"Nat Rev Mol Cell Biol"},{"key":"261_CR16","doi-asserted-by":"publisher","first-page":"351","DOI":"10.1111\/j.1365-313X.2011.04691.x","volume":"68","author":"NB Eloy","year":"2011","unstructured":"Eloy NB, de Freitas LM, Van Damme D, Vanhaeren H, Gonzalez N, De Milde L, et al. The APC\/C subunit 10 plays an essential role in cell proliferation during leaf development. Plant J. 2011;68:351\u201363. https:\/\/doi.org\/10.1111\/j.1365-313X.2011.04691.x.","journal-title":"Plant J"},{"key":"261_CR17","doi-asserted-by":"publisher","DOI":"10.1016\/j.pbi.2021.102049","volume":"63","author":"SN Freytes","year":"2021","unstructured":"Freytes SN, Canelo M, Cerd\u00e1n PD. Regulation of flowering time: when and where? Curr Opin Plant Biol. 2021;63:102049. https:\/\/doi.org\/10.1016\/j.pbi.2021.102049.","journal-title":"Curr Opin Plant Biol"},{"key":"261_CR18","doi-asserted-by":"publisher","first-page":"459","DOI":"10.1111\/tpj.16993","volume":"120","author":"F Gong","year":"2024","unstructured":"Gong F, Jing W, Jin W, Liu H, Zhang Y, Wang R, et al. RhMYC2 controls petal size through synergistic regulation of jasmonic acid and cytokinin signaling in rose. Plant J. 2024;120:459\u201372. https:\/\/doi.org\/10.1111\/tpj.16993.","journal-title":"Plant J"},{"key":"261_CR19","doi-asserted-by":"publisher","first-page":"332","DOI":"10.1016\/j.tplants.2012.02.003","volume":"17","author":"N Gonzalez","year":"2012","unstructured":"Gonzalez N, Vanhaeren H, Inz\u00e9 D. Leaf size control: complex coordination of cell division and expansion. Trends Plant Sci. 2012;17:332\u201340. https:\/\/doi.org\/10.1016\/j.tplants.2012.02.003.","journal-title":"Trends Plant Sci"},{"key":"261_CR20","doi-asserted-by":"publisher","first-page":"1489","DOI":"10.1111\/tpj.16031","volume":"112","author":"Y Guan","year":"2022","unstructured":"Guan Y, Ding L, Jiang J, Jia D, Li S, Jin L, et al. The TIFY family protein CmJAZ1-like negatively regulates petal size via interaction with the bHLH transcription factor CmBPE2 in Chrysanthemum morifolium. Plant J. 2022;112:1489\u2013506. https:\/\/doi.org\/10.1111\/tpj.16031.","journal-title":"Plant J"},{"key":"261_CR21","doi-asserted-by":"publisher","unstructured":"Guan YX, Wong CE, Zhang QY, Peng DH, Lan SR, Chen FD, et al. Sizing up beauty: mechanisms of petal size regulation in ornamental plants. Plant Physiol. 2025;198. https:\/\/doi.org\/10.1093\/plphys\/kiaf198.","DOI":"10.1093\/plphys\/kiaf198"},{"key":"261_CR22","doi-asserted-by":"publisher","first-page":"1097","DOI":"10.1111\/nph.19205","volume":"240","author":"Q Guo","year":"2023","unstructured":"Guo Q, Jing Y, Gao Y, Liu Y, Fang X, Lin R. The PIF1\/PIF3-MED25-HDA19 transcriptional repression complex regulates phytochrome signaling in Arabidopsis. New Phytol. 2023;240:1097\u2013115. https:\/\/doi.org\/10.1111\/nph.19205.","journal-title":"New Phytol"},{"key":"261_CR23","doi-asserted-by":"publisher","first-page":"36","DOI":"10.1016\/j.pbi.2013.11.005","volume":"17","author":"J Hepworth","year":"2014","unstructured":"Hepworth J, Lenhard M. Regulation of plant lateral-organ growth by modulating cell number and size. Curr Opin Plant Biol. 2014;17:36\u201342. https:\/\/doi.org\/10.1016\/j.pbi.2013.11.005.","journal-title":"Curr Opin Plant Biol"},{"key":"261_CR24","doi-asserted-by":"publisher","first-page":"1951","DOI":"10.1105\/tpc.013557","volume":"15","author":"Y Hu","year":"2003","unstructured":"Hu Y, Xie Q, Chua NH. The Arabidopsis auxin-inducible gene ARGOS controls lateral organ size. Plant Cell. 2003;15:1951\u201361. https:\/\/doi.org\/10.1105\/tpc.013557.","journal-title":"Plant Cell"},{"key":"261_CR25","doi-asserted-by":"publisher","first-page":"1186","DOI":"10.1093\/jxb\/erac251","volume":"74","author":"H Huang","year":"2025","unstructured":"Huang H, Chen Y, Wang S, Qi T, Song S. Jasmonate action and crosstalk in flower development and fertility. J Exp Bot. 2025;74:1186\u201397. https:\/\/doi.org\/10.1093\/jxb\/erac251.","journal-title":"J Exp Bot"},{"key":"261_CR26","doi-asserted-by":"publisher","unstructured":"Huang R, Huang T, Irish VF. Do epigenetic timers control petal development? Front Plant Sci. 2021;12. https:\/\/doi.org\/10.3389\/fpls.2021.709360.","DOI":"10.3389\/fpls.2021.709360"},{"key":"261_CR27","doi-asserted-by":"publisher","first-page":"1267","DOI":"10.1093\/mp\/ssu049","volume":"7","author":"B Huot","year":"2014","unstructured":"Huot B, Yao J, Montgomery BL, He SY. Growth-defense tradeoffs in plants: a balancing act to optimize fitness. Mol Plant. 2014;7:1267\u201387. https:\/\/doi.org\/10.1093\/mp\/ssu049.","journal-title":"Mol Plant"},{"key":"261_CR28","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1186\/s43897-022-00030-3","volume":"2","author":"R Jiang","year":"2022","unstructured":"Jiang R, Yuan W, Yao W, Jin X, Wang X, Wang Y. A regulatory GhBPE-GhPRGL module maintains ray petal length in Gerbera hybrida. Mol Horticulture. 2022;2:9. https:\/\/doi.org\/10.1186\/s43897-022-00030-3.","journal-title":"Mol Horticulture"},{"key":"261_CR29","doi-asserted-by":"publisher","first-page":"381","DOI":"10.1093\/jxb\/erae331","volume":"76","author":"W Jin","year":"2025","unstructured":"Jin W, Gong F, Zhang Y, Wang R, Liu H, Wei Y, et al. Cytokinin-responsive RhRR1-RhSCL28 transcription factor module positively regulates petal size by promoting cell division in rose. J Exp Bot. 2025;76:381\u201392. https:\/\/doi.org\/10.1093\/jxb\/erae331.","journal-title":"J Exp Bot"},{"key":"261_CR30","doi-asserted-by":"publisher","first-page":"7106","DOI":"10.1038\/s41467-023-42914-y","volume":"14","author":"W Jing","year":"2023","unstructured":"Jing W, Gong F, Liu G, Deng Y, Liu J, Yang W, et al. Petal size is controlled by the MYB73\/TPL\/HDA19-miR159-CKX6 module regulating cytokinin catabolism in Rosa hybrida. Nat Commun. 2023;14:7106. https:\/\/doi.org\/10.1038\/s41467-023-42914-y.","journal-title":"Nat Commun"},{"key":"261_CR31","doi-asserted-by":"publisher","first-page":"1916","DOI":"10.1104\/pp.109.141119","volume":"150","author":"B Krizek","year":"2009","unstructured":"Krizek B. AINTEGUMENTA and AINTEGUMENTA-LIKE6 act redundantly to regulate Arabidopsis floral growth and patterning. Plant Physiol. 2009;150:1916\u201329. https:\/\/doi.org\/10.1104\/pp.109.141119.","journal-title":"Plant Physiol"},{"key":"261_CR32","doi-asserted-by":"publisher","first-page":"1427","DOI":"10.1093\/jxb\/ert025","volume":"64","author":"BA Krizek","year":"2013","unstructured":"Krizek BA, Anderson JT. Control of flower size. J Exp Bot. 2013;64:1427\u201337. https:\/\/doi.org\/10.1093\/jxb\/ert025.","journal-title":"J Exp Bot"},{"key":"261_CR33","doi-asserted-by":"publisher","first-page":"106","DOI":"10.1105\/tpc.18.00405","volume":"31","author":"Y Liu","year":"2019","unstructured":"Liu Y, Du M, Deng L, Shen J, Fang M, Chen Q, et al. MYC2 regulates the termination of jasmonate signaling via an autoregulatory negative feedback loop. Plant Cell. 2019;31:106\u201327. https:\/\/doi.org\/10.1105\/tpc.18.00405.","journal-title":"Plant Cell"},{"issue":"16","key":"261_CR34","doi-asserted-by":"publisher","first-page":"5075","DOI":"10.1093\/jxb\/ert296","volume":"64","author":"J Luo","year":"2013","unstructured":"Luo J, Ma N, Pei H, Chen J, Li J, Gao J. A DELLA gene, RhGAI1, is a direct target of EIN3 and mediates ethylene-regulated rose petal cell expansion via repressing the expression of RhCesA2. J Exp Bot. 2013;64(16):5075\u201384. https:\/\/doi.org\/10.1093\/jxb\/ert296.","journal-title":"J Exp Bot"},{"issue":"4","key":"261_CR35","doi-asserted-by":"publisher","first-page":"3511","DOI":"10.3390\/ijms24043511","volume":"24","author":"L Luo","year":"2023","unstructured":"Luo L, Wang Y, Qiu L, Han X, Zhu Y, Liu L, et al. MYC2: a master switch for plant physiological processes and specialized metabolite synthesis. Int J Mol Sci. 2023;24(4):3511. https:\/\/doi.org\/10.3390\/ijms24043511.","journal-title":"Int J Mol Sci"},{"issue":"12","key":"261_CR36","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1003114","volume":"8","author":"M Luo","year":"2012","unstructured":"Luo M, Yu CW, Chen FF, Zhao L, Tian G, Liu X, et al. Histone deacetylase HDA6 is functionally associated with AS1 in repression of KNOX genes in arabidopsis. PLoS Genet. 2012;8(12):e1003114. https:\/\/doi.org\/10.1371\/journal.pgen.1003114.","journal-title":"PLoS Genet"},{"issue":"2","key":"261_CR37","doi-asserted-by":"publisher","first-page":"894","DOI":"10.1104\/pp.108.120154","volume":"148","author":"N Ma","year":"2008","unstructured":"Ma N, Xue J, Li Y, Liu X, Dai F, Jia W, et al. Rh-PIP2;1, a rose aquaporin gene, is involved in ethylene-regulated petal expansion. Plant Physiol. 2008;148(2):894\u2013907. https:\/\/doi.org\/10.1104\/pp.108.120154.","journal-title":"Plant Physiol"},{"key":"261_CR38","doi-asserted-by":"publisher","unstructured":"Ma X, Li D, Cai J, Yang S, Wang D, Zhang Q, et al. Auxin response factor, RhARF8 contributes to rose flower color fading via regulating anthocyanin biosynthesis by directly activating RhCHSa\/c promoter activity. Ornament Plant Res. 2025;5:1\u201312. https:\/\/doi.org\/10.48130\/opr-0025-0019.","DOI":"10.48130\/opr-0025-0019"},{"issue":"11","key":"261_CR39","doi-asserted-by":"publisher","first-page":"761","DOI":"10.1038\/nrg2901","volume":"11","author":"S Malik","year":"2010","unstructured":"Malik S, Roeder RG. The metazoan Mediator co-activator complex as an integrative hub for transcriptional regulation. Nat Rev Genet. 2010;11(11):761\u201372. https:\/\/doi.org\/10.1038\/nrg2901.","journal-title":"Nat Rev Genet"},{"issue":"2","key":"261_CR40","doi-asserted-by":"publisher","first-page":"942","DOI":"10.1073\/pnas.97.2.942","volume":"97","author":"Y Mizukami","year":"2000","unstructured":"Mizukami Y, Fischer RL. Plant organ size control: AINTEGUMENTA regulates growth and cell numbers during organogenesis. Proc Natl Acad Sci U S A. 2000;97(2):942\u20137. https:\/\/doi.org\/10.1073\/pnas.97.2.942.","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"2","key":"261_CR41","doi-asserted-by":"publisher","first-page":"775","DOI":"10.1104\/pp.113.223388","volume":"163","author":"H Pei","year":"2013","unstructured":"Pei H, Ma N, Tian J, Luo J, Chen J, Li J, et al. An NAC transcription factor controls ethylene-regulated cell expansion in flower petals. Plant Physiol. 2013;163(2):775\u201391. https:\/\/doi.org\/10.1104\/pp.113.223388.","journal-title":"Plant Physiol"},{"issue":"4","key":"261_CR42","doi-asserted-by":"publisher","first-page":"2188","DOI":"10.1093\/plphys\/kiae004","volume":"194","author":"JM Robil","year":"2024","unstructured":"Robil JM. Two birds with one stone: how RhRAP2.4L controls both cell proliferation and expansion to regulate petal growth in rose. Plant Physiol. 2024;194(4):2188\u201390. https:\/\/doi.org\/10.1093\/plphys\/kiae004.","journal-title":"Plant Physiol"},{"issue":"3","key":"261_CR43","doi-asserted-by":"publisher","first-page":"307","DOI":"10.1007\/s11103-009-9525-7","volume":"71","author":"CA Rojas","year":"2009","unstructured":"Rojas CA, Eloy NB, Lima MF, Rodrigues RL, Franco LO, Himanen K, et al. Overexpression of the Arabidopsis anaphase promoting complex subunit CDC27a increases growth rate and organ size. Plant Mol Biol. 2009;71(3):307\u201318. https:\/\/doi.org\/10.1007\/s11103-009-9525-7.","journal-title":"Plant Mol Biol"},{"key":"261_CR44","doi-asserted-by":"publisher","DOI":"10.3389\/fpls.2022.868874","volume":"13","author":"C Song","year":"2022","unstructured":"Song C, Cao Y, Dai J, Li G, Manzoor MA, Chen C, et al. The multifaceted roles of MYC2 in plants: toward transcriptional reprogramming and stress tolerance by Jasmonate signaling. Front Plant Sci. 2022;13:868874. https:\/\/doi.org\/10.3389\/fpls.2022.868874.","journal-title":"Front Plant Sci"},{"issue":"1","key":"261_CR45","doi-asserted-by":"publisher","first-page":"582","DOI":"10.1093\/plphys\/kiac581","volume":"192","author":"U Shapulatov","year":"2023","unstructured":"Shapulatov U, van Zanten M, van Hoogdalem M, Meisenburg M, van Hall A, Kappers I, et al. The mediator complex subunit MED25 interacts with HDA9 and PIF4 to regulate thermomorphogenesis. Plant Physiol. 2023;192(1):582\u2013600. https:\/\/doi.org\/10.1093\/plphys\/kiac581.","journal-title":"Plant Physiol"},{"issue":"12","key":"261_CR46","doi-asserted-by":"publisher","first-page":"1601","DOI":"10.3390\/plants11121601","volume":"11","author":"G Suzuki","year":"2022","unstructured":"Suzuki G, Fukuda M, Lucob-Agustin N, Inukai Y, Gomi K. The mutation of rice MEDIATOR25, OsMED25, induces rice bacterial blight resistance through altering Jasmonate- and Auxin-signaling. Plants (Basel). 2022;11(12):1601. https:\/\/doi.org\/10.3390\/plants11121601.","journal-title":"Plants (Basel)"},{"issue":"16","key":"261_CR47","doi-asserted-by":"publisher","first-page":"3912","DOI":"10.1038\/sj.emboj.7601270","volume":"25","author":"J Sz\u00e9csi","year":"2006","unstructured":"Sz\u00e9csi J, Joly C, Bordji K, Varaud E, Cock JM, Dumas C, et al. BIGPETALp, a bHLH transcription factor is involved in the control of Arabidopsis petal size. EMBO J. 2006;25(16):3912\u201320. https:\/\/doi.org\/10.1038\/sj.emboj.7601270.","journal-title":"EMBO J"},{"issue":"3","key":"261_CR48","doi-asserted-by":"publisher","first-page":"973","DOI":"10.1105\/tpc.110.081653","volume":"23","author":"E Varaud","year":"2011","unstructured":"Varaud E, Brioudes F, Sz\u00e9csi J, Leroux J, Brown S, Perrot-Rechenmann C, et al. AUXIN RESPONSE FACTOR8 regulates Arabidopsis petal growth by interacting with the bHLH transcription factor BIGPETALp. Plant Cell. 2011;23(3):973\u201383. https:\/\/doi.org\/10.1105\/tpc.110.081653.","journal-title":"Plant Cell"},{"issue":"11","key":"261_CR49","doi-asserted-by":"publisher","first-page":"1461","DOI":"10.1016\/j.molp.2017.08.007","volume":"10","author":"H Wang","year":"2017","unstructured":"Wang H, Li Y, Pan J, Lou D, Hu Y, Yu D. The bHLH transcription factors MYC2, MYC3, and MYC4 are required for Jasmonate-mediated inhibition of flowering in Arabidopsis. Mol Plant. 2017;10(11):1461\u20134. https:\/\/doi.org\/10.1016\/j.molp.2017.08.007.","journal-title":"Mol Plant"},{"key":"261_CR50","doi-asserted-by":"publisher","first-page":"248","DOI":"10.1016\/j.plantsci.2018.12.008","volume":"280","author":"J Wang","year":"2019","unstructured":"Wang J, Guan Y, Ding L, Li P, Zhao W, Jiang J, et al. The CmTCP20 gene regulates petal elongation growth in Chrysanthemum morifolium. Plant Sci. 2019;280:248\u201357. https:\/\/doi.org\/10.1016\/j.plantsci.2018.12.008.","journal-title":"Plant Sci"},{"issue":"5","key":"261_CR51","doi-asserted-by":"publisher","DOI":"10.1093\/hr\/uhaf025","volume":"12","author":"W Wang","year":"2025","unstructured":"Wang W, Sun J, Fan C, Yuan G, Zhou R, Lu J, et al. RcSRR1 interferes with the RcCSN5B-mediated deneddylation of RcCRL4 to modulate RcCO proteolysis and prevent rose flowering under red light. Hortic Res. 2025;12(5):uhaf025. https:\/\/doi.org\/10.1093\/hr\/uhaf025.","journal-title":"Hortic Res"},{"issue":"6","key":"261_CR52","doi-asserted-by":"publisher","first-page":"2338","DOI":"10.1093\/plphys\/kiad657","volume":"194","author":"Y Wang","year":"2024","unstructured":"Wang Y, Qin M, Zhang G, Lu J, Zhang C, Ma N, et al. Transcription factor RhRAP2.4L orchestrates cell proliferation and expansion to control petal size in rose. Plant Physiol. 2024;194(6):2338\u201353. https:\/\/doi.org\/10.1093\/plphys\/kiad657.","journal-title":"Plant Physiol"},{"issue":"5\u20136","key":"261_CR53","doi-asserted-by":"publisher","first-page":"513","DOI":"10.1387\/ijdb.051998jw","volume":"49","author":"J Weiss","year":"2005","unstructured":"Weiss J, Delgado-Benarroch L, Egea-Cortines M. Genetic control of floral size and proportions. Int J Dev Biol. 2005;49(5\u20136):513\u201325. https:\/\/doi.org\/10.1387\/ijdb.051998jw.","journal-title":"Int J Dev Biol"},{"issue":"21","key":"261_CR54","doi-asserted-by":"publisher","first-page":"4545","DOI":"10.1242\/dev.071423","volume":"138","author":"R Xu","year":"2011","unstructured":"Xu R, Li Y. Control of final organ size by mediator complex subunit 25 in Arabidopsis thaliana. Development. 2011;138(21):4545\u201354. https:\/\/doi.org\/10.1242\/dev.071423.","journal-title":"Development"},{"issue":"7","key":"261_CR55","doi-asserted-by":"publisher","first-page":"1953","DOI":"10.1105\/tpc.105.032060","volume":"17","author":"V Yadav","year":"2005","unstructured":"Yadav V, Mallappa C, Gangappa SN, Bhatia S, Chattopadhyay S. A basic helix-loop-helix transcription factor in Arabidopsis, MYC2, acts as a repressor of blue light-mediated photomorphogenic growth. Plant Cell. 2005;17(7):1953\u201366. https:\/\/doi.org\/10.1105\/tpc.105.032060.","journal-title":"Plant Cell"},{"issue":"3","key":"261_CR56","doi-asserted-by":"publisher","first-page":"695","DOI":"10.1016\/j.bbrc.2018.11.082","volume":"508","author":"L Yuan","year":"2019","unstructured":"Yuan L, Chen X, Chen H, Wu K, Huang S. Histone deacetylases HDA6 and HDA9 coordinately regulate valve cell elongation through affecting auxin signaling in Arabidopsis. Biochem Biophys Res Commun. 2019;508(3):695\u2013700. https:\/\/doi.org\/10.1016\/j.bbrc.2018.11.082.","journal-title":"Biochem Biophys Res Commun"},{"key":"261_CR57","doi-asserted-by":"publisher","first-page":"44","DOI":"10.1016\/j.pbi.2015.05.024","volume":"27","author":"Z Yuan","year":"2015","unstructured":"Yuan Z, Zhang D. Roles of jasmonate signalling in plant inflorescence and flower development. Curr Opin Plant Biol. 2015;27:44\u201351. https:\/\/doi.org\/10.1016\/j.pbi.2015.05.024.","journal-title":"Curr Opin Plant Biol"},{"issue":"7","key":"261_CR58","doi-asserted-by":"publisher","DOI":"10.1016\/j.xplc.2024.100936","volume":"5","author":"J Zhao","year":"2024","unstructured":"Zhao J, Wang J, Liu J, Zhang P, Kudoyarova G, Liu C. Spatially distributed cytokinins: metabolism, signaling, and transport. Plant Commun. 2024;5(7):100936. https:\/\/doi.org\/10.1016\/j.xplc.2024.100936.","journal-title":"Plant Commun"},{"key":"261_CR59","doi-asserted-by":"publisher","first-page":"78","DOI":"10.1016\/j.pbi.2020.06.006","volume":"57","author":"Q Zhai","year":"2020","unstructured":"Zhai Q, Deng L, Li C. Mediator subunit MED25: at the nexus of jasmonate signaling. Curr Opin Plant Biol. 2020;57:78\u201386. https:\/\/doi.org\/10.1016\/j.pbi.2020.06.006.","journal-title":"Curr Opin Plant Biol"}],"container-title":["Molecular Horticulture"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s43897-026-00261-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s43897-026-00261-8","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s43897-026-00261-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T23:02:18Z","timestamp":1788476538000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1186\/s43897-026-00261-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,4]]},"references-count":59,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["261"],"URL":"https:\/\/doi.org\/10.1186\/s43897-026-00261-8","relation":{},"ISSN":["2730-9401"],"issn-type":[{"value":"2730-9401","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,4]]},"assertion":[{"value":"29 December 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 June 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 September 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Not applicable.","order":1,"name":"Ethics","label":"Ethics approval and consent to participate","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","label":"Consent for publication","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare that they have no competing interests.","order":3,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"65"}}