{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T00:38:56Z","timestamp":1792543136829,"version":"4.5.0"},"reference-count":8,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T00:00:00Z","timestamp":1792454400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T00:00:00Z","timestamp":1792454400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Gen Thorac Cardiovasc Surg Cases"],"DOI":"10.1186\/s44215-026-00282-1","type":"journal-article","created":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T11:25:05Z","timestamp":1792495505000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Perioperative management of acute type A aortic dissection using extended half-life factor IX (Alprolix) in a patient with severe hemophilia B: a case report"],"prefix":"10.1186","volume":"5","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-9614-2400","authenticated-orcid":false,"given":"Tessho","family":"Kitamura","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yutaro","family":"Ryu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shun","family":"Nakaji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinichiro","family":"Taniguchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,10,20]]},"reference":[{"key":"282_CR1","doi-asserted-by":"publisher","first-page":"e61","DOI":"10.1016\/j.athoracsur.2011.10.028","volume":"93","author":"A Furutachi","year":"2012","unstructured":"Furutachi A, Furukawa K, Oda Y, Morita S. Total arch replacement for acute aortic dissection (Stanford A) in a patient with hemophilia A. Ann Thorac Surg. 2012;93:e61\u20132. https:\/\/doi.org\/10.1016\/j.athoracsur.2011.10.028.","journal-title":"Ann Thorac Surg"},{"key":"282_CR2","doi-asserted-by":"publisher","first-page":"e109","DOI":"10.1111\/hae.12879","volume":"22","author":"M Takeyama","year":"2016","unstructured":"Takeyama M, Nogami K, Shida Y, Yada K, Hirose T, Hayata Y, et al. Successful haemostatic management of replacement of the ascending aorta for type A acute aortic dissection in a patient with mild haemophilia B. Haemophilia. 2016;22:e109\u201311. https:\/\/doi.org\/10.1111\/hae.12879.","journal-title":"Haemophilia"},{"key":"282_CR3","doi-asserted-by":"crossref","first-page":"e75","DOI":"10.1111\/hae.13649","volume":"25","author":"A Iorio","year":"2019","unstructured":"Iorio A, Stonebraker JS, Chambost H, Makris M, Coffin D, Herr C, et al. Establishing the prevalence and prevalence at birth of hemophilia in males: a meta-analytic approach. Haemophilia. 2019;25:e75\u201385.","journal-title":"Haemophilia"},{"key":"282_CR4","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1016\/j.blre.2013.06.002","volume":"27","author":"M Franchini","year":"2013","unstructured":"Franchini M, Mannucci PM. Hemophilia A in the third millennium. Blood Rev. 2013;27:179\u201384. https:\/\/doi.org\/10.1016\/j.blre.2013.06.002.","journal-title":"Blood Rev"},{"issue":"Suppl 6","key":"282_CR5","first-page":"1","volume":"26","author":"World Federation of Hemophilia","year":"2020","unstructured":"World Federation of Hemophilia. WFH Guidelines for the Management of Hemophilia. Haemophilia. 2020;26(Suppl 6):1\u2013158. 3rd ed.","journal-title":"Haemophilia"},{"key":"282_CR6","doi-asserted-by":"publisher","first-page":"246","DOI":"10.1053\/j.jvca.2020.09.118","volume":"36","author":"J Kwak","year":"2022","unstructured":"Kwak J, Mazzeffi M, Boggio LN, Simpson ML, Tanaka KA. Hemophilia: a review of perioperative management for cardiac surgery. J Cardiothorac Vasc Anesth. 2022;36:246\u201357. https:\/\/doi.org\/10.1053\/j.jvca.2020.09.118.","journal-title":"J Cardiothorac Vasc Anesth"},{"key":"282_CR7","doi-asserted-by":"publisher","first-page":"1287","DOI":"10.1517\/14712598.2013.819339","volume":"13","author":"AD Shapiro","year":"2013","unstructured":"Shapiro AD. Development of long-acting recombinant FVIII and FIX Fc fusion proteins for the management of hemophilia. Expert Opin Biol Ther. 2013;13:1287\u201397. https:\/\/doi.org\/10.1517\/14712598.2013.819339.","journal-title":"Expert Opin Biol Ther"},{"key":"282_CR8","doi-asserted-by":"publisher","first-page":"2288","DOI":"10.1016\/j.jtcvs.2019.04.111","volume":"159","author":"HK Sandhu","year":"2020","unstructured":"Sandhu HK, Tanaka A, Dahotre S, Charlton-Ouw KM, Miller CC III, Estrera AL, et al. Propensity and impact of autologous platelet rich plasma use in acute type A dissection. J Thorac Cardiovasc Surg. 2020;159:2288\u2013e22971. https:\/\/doi.org\/10.1016\/j.jtcvs.2019.04.111.","journal-title":"J Thorac Cardiovasc Surg"}],"container-title":["General Thoracic and Cardiovascular Surgery Cases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s44215-026-00282-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s44215-026-00282-1","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s44215-026-00282-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T00:05:49Z","timestamp":1792541149000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s44215-026-00282-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10,20]]},"references-count":8,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["282"],"URL":"https:\/\/doi.org\/10.1186\/s44215-026-00282-1","relation":{},"ISSN":["2731-6203"],"issn-type":[{"value":"2731-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,10,20]]},"assertion":[{"value":"16 May 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 September 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 October 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Ethical approval was waived by our institution for this case report. Written informed consent to participate was obtained from the patient.","order":1,"name":"Ethics","label":"Ethics approval and consent to participate","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Written informed consent for publication of the case report and accompanying images was obtained from the patient.","order":2,"name":"Ethics","label":"Consent for publication","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare that they have no competing interests.","order":3,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"47"}}