{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T01:53:40Z","timestamp":1773280420623,"version":"3.50.1"},"reference-count":44,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2001,8,20]],"date-time":"2001-08-20T00:00:00Z","timestamp":998265600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Dermatol"],"DOI":"10.1186\/1471-5945-1-4","type":"journal-article","created":{"date-parts":[[2002,10,11]],"date-time":"2002-10-11T18:40:44Z","timestamp":1034361644000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Transcutaneous flow related variables measured in vivo: the effects of gender"],"prefix":"10.1186","volume":"1","author":[{"given":"Lu\u00eds Monteiro","family":"Rodrigues","sequence":"first","affiliation":[]},{"given":"Pedro Contreiras","family":"Pinto","sequence":"additional","affiliation":[]},{"given":"Ant\u00f3nio","family":"Leal","sequence":"additional","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2001,8,20]]},"reference":[{"key":"4_CR1","first-page":"185","volume-title":"in \"\"Hand Book of Non-Invasive Methods and the Skin\" Ed. J. Serup & G.B.E Jemec, CRC Press, Boca Raton,","author":"H Takiwaki","year":"1995","unstructured":"Takiwaki H: Measurement of transcutaneous oxygen tension,.\n                           in \"\"Hand Book of Non-Invasive Methods and the Skin\" Ed. J. Serup & G.B.E Jemec, CRC Press, Boca Raton, 1995, 185\u2013195."},{"key":"4_CR2","first-page":"197","volume-title":"in \"Handbook of non-invasive Methods and the Skin\", Eds. J. Serup & G. Gemec, CRC Press, Boca Raton,","author":"CN Nickelsen","year":"1995","unstructured":"Nickelsen CN: Measurement of Transcutaneous pCO\n                           \n                              2\n                           \n                           ,.\n                           in \"Handbook of non-invasive Methods and the Skin\", Eds. J. Serup & G. Gemec, CRC Press, Boca Raton, 1995, 197\u2013200."},{"key":"4_CR3","first-page":"380","volume":"13","author":"L Rodrigues","year":"1998","unstructured":"Rodrigues L, Ferro IZ, Galego N, Pinto P, Silva N, Rey-Salgueiros Y: Study on the application of transcutaneous pO\n                           \n                              2\n                           \n                           and pCO\n                           \n                              2\n                           \n                           monitoring to the in vivo functional characterisation of the normal human skin,.\n                           Piel span 1998, 13: 380\u2013388.","journal-title":"Piel span"},{"key":"4_CR4","volume-title":"Skin Pharmacol AppI Skin Physiol","author":"E Berardesca","year":"2001","unstructured":"Berardesca E, Leveque JL, Masson Ph, the EEMCO Group, EEMCO guidance for the measurement of skin microcirculation: Skin Pharmacol AppI Skin Physiol 2001, in press."},{"issue":"4","key":"4_CR5","first-page":"379","volume":"24","author":"I Got","year":"1998","unstructured":"Got I: Transcutaneous oxygen pressure (TcPO\n                           \n                              2\n                           \n                           ): advantages and limitations.\n                           Diabetes Metab 1998,24(4):379\u201384.","journal-title":"Diabetes Metab"},{"issue":"3","key":"4_CR6","doi-asserted-by":"publisher","first-page":"664","DOI":"10.1016\/S0735-1097(97)00216-7","volume":"30","author":"GP Hanna","year":"1997","unstructured":"Hanna GP, Fujise K, Kjellgren O, Feld S, Fife C, Schroth G, Clanton T, Anderson V, Smalling RW: Infra-popliteal transcatheter interventions for limb salvage in diabetic patients: importance of aggressive interventional approach and role of transcutaneous oximetry.\n                           J Am Coll Cardiol 1997,30(3):664\u20139. 10.1016\/S0735-1097(97)00216-7","journal-title":"J Am Coll Cardiol"},{"issue":"1","key":"4_CR7","doi-asserted-by":"publisher","first-page":"114","DOI":"10.1016\/S0741-5214(99)70183-7","volume":"30","author":"DT Ubbink","year":"1999","unstructured":"Ubbink DT, Spincemaille GH, Reneman RS, Jacobs MJ: Prediction of imminent amputation in patients with non-reconstructible leg ischemia by means of microcirculatory investigations.\n                           J Vasc Surg 1999,30(1):114\u201321.","journal-title":"J Vasc Surg"},{"key":"4_CR8","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1016\/0002-9610(82)90604-3","volume":"144","author":"RA White","year":"1982","unstructured":"White RA, Nolan L, Harley D, Long J, Klein S, Tremper K, Nelson R, Trabiski J, Shoemaker W: Non-invasive evaluation of peripheral disease using transcutaneous oxygen tension,.\n                           Am J Surg 1982, 144: 68\u201375. 10.1016\/0002-9610(82)90604-3","journal-title":"Am J Surg"},{"key":"4_CR9","doi-asserted-by":"publisher","first-page":"690","DOI":"10.1001\/archsurg.1984.01390180054009","volume":"119","author":"CJ Hauser","year":"1984","unstructured":"Hauser CJ, Klein SR, Mehringer CM, Apple P, Shoemaker WC: Superiority of transcutaneous oximetry in non-invasive vascular diagnosis in patients with diabetes,.\n                           Arch Surg 1984, 119: 690\u2013694.","journal-title":"Arch Surg"},{"issue":"4","key":"4_CR10","first-page":"167","volume":"15","author":"AM Thunstrom","year":"1979","unstructured":"Thunstrom AM, Stafford M, Severinghaus JW: A two temperature, two pO\n                           \n                              2\n                           \n                           method of estimating the determinants of tcpO\n                           \n                              2\n                           \n                           ,.\n                           Birth Defects Original Article Series 1979,15(4):167\u2013182.","journal-title":"Birth Defects Original Article Series"},{"key":"4_CR11","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1111\/j.1399-6576.1978.tb01386.x","volume":"suppl.68","author":"JW Severinghaus","year":"1978","unstructured":"Severinghaus JW, Stafford M, Thunstrom AM: Estimation of skin metabolism and blood flow with tcpO\n                           \n                              2\n                           \n                           and tcpCO\n                           \n                              2\n                           \n                           electrodes by cuff occlusion of the circulation,.\n                           Acta Anaesthesiol Scand 1978, suppl.68: 9\u201315.","journal-title":"Acta Anaesthesiol Scand"},{"key":"4_CR12","first-page":"81","volume":"2","author":"T Tenland","year":"1983","unstructured":"Tenland T, Salerud EG, Nilsson GE, Ake P: Spatial and temporal variations in human skin blood flow,.\n                           Int J Microcir Clin Exp 1983, 2: 81\u201390.","journal-title":"Int J Microcir Clin Exp"},{"key":"4_CR13","doi-asserted-by":"publisher","first-page":"178","DOI":"10.3109\/03091909009009955","volume":"14","author":"AN Obeid","year":"1990","unstructured":"Obeid AN, Barnett NJ, Dougherty G, Ward G: A critical review of laser Doppler flowmetry,.\n                           J Med Eng Technol 1990, 14: 178\u2013181.","journal-title":"J Med Eng Technol"},{"key":"4_CR14","first-page":"81","volume":"2","author":"T Tenland","year":"1983","unstructured":"Tenland T, Salerud EG, Nilsson GE, Ake P: Spatial and temporal variations in human skin blood flow,.\n                           Int J Microcirc Clin Exp 1983, 2: 81\u201390.","journal-title":"Int J Microcirc Clin Exp"},{"key":"4_CR15","first-page":"107","volume":"6","author":"IM Braverman","year":"1990","unstructured":"Braverman IM, Keh A, Goldminz D: Correlation of laser doppler wave patternswith underlying microvascular anatomy,.\n                           J Invest Dermatol 1990, 6: 107\u2013118.","journal-title":"J Invest Dermatol"},{"key":"4_CR16","doi-asserted-by":"publisher","first-page":"44","DOI":"10.1159\/000056333","volume":"14","author":"M Stucker","year":"2001","unstructured":"Stucker M, Steinberg J, Memmel U, Avermaete A, Hoffmann K: Differences in the two-dimensionally measured laser doppler flow at different skin localisations,.\n                           Skin Pharmacol AppI Skin Physiol 2001, 14: 44\u201351. 10.1159\/000056333","journal-title":"Skin Pharmacol AppI Skin Physiol"},{"key":"4_CR17","first-page":"41","volume":"2","author":"LC Clark","year":"1956","unstructured":"Clark LC: Monitor and control of blood and oxygen in tissue,.\n                           Trans Am Soc Artif Intern Organs 1956, 2: 41\u201348.","journal-title":"Trans Am Soc Artif Intern Organs"},{"key":"4_CR18","doi-asserted-by":"publisher","first-page":"269","DOI":"10.3109\/00365517309082431","volume":"31","author":"R Huch","year":"1973","unstructured":"Huch R, Huch A, Arner B, Rooth G: Continuos transcutaneous oxygen measured with a heat electrode,.\n                           Scabd J CIin Lab Invest 1973, 31: 269\u2013273.","journal-title":"Scabd J CIin Lab Invest"},{"key":"4_CR19","first-page":"S200","volume":"11 (Supl.1)","author":"L Rodrigues","year":"2000","unstructured":"Rodrigues L, Leal A, Ferreira R, Leal F, Fernandes M, Pinto P: Non-invasive in vivo evaluation of cutaneous metabolic activity, Europp.\n                           J Pharm Sciences 2000, 11 (Supl.1): S200.","journal-title":"J Pharm Sciences"},{"key":"4_CR20","first-page":"35","volume-title":"Huch R & Huch A Eds M Dekker N.Y","author":"P Jaszczak","year":"1983","unstructured":"Jaszczak P, Poulsen J: tc pO\n                           \n                              2\n                           \n                           dependence on a sufficient blood flow, in Continuos Transcutaneous Blood Gas Monitoring,.\n                           Huch R & Huch A Eds M Dekker N.Y 1983, 35\u201343."},{"key":"4_CR21","first-page":"649","volume-title":"in \"Continuos Transcutaneous Bloogd Gas Monitoring\" Huch R. & Huch A Eds., Marcel Dekker Publ., NY, pp","author":"WT Workman","year":"1983","unstructured":"Workman WT, Sceffield PJ: Continuos transcutaneous oxygen monitoring in smokers under normobaric and hyperbaric oxygen conditions;.\n                           in \"Continuos Transcutaneous Bloogd Gas Monitoring\" Huch R. & Huch A Eds., Marcel Dekker Publ., NY, pp 1983, 649."},{"key":"4_CR22","doi-asserted-by":"publisher","first-page":"873","DOI":"10.1177\/000331978803901004","volume":"39; 10","author":"L Lusiani","year":"1988","unstructured":"Lusiani L, Visona A, Nicolin P, Papesso B, Pagnan A: Transcutaneous oxygen tension measurement as a diagnostic tool in patients with peripheral vascular disease,.\n                           Angiology 1988, 39; 10: 873\u2013880.","journal-title":"Angiology"},{"key":"4_CR23","doi-asserted-by":"crossref","first-page":"1613","DOI":"10.1152\/jappl.1986.61.5.1613","volume":"61","author":"JM Johnson","year":"1986","unstructured":"Johnson JM: Non-thermoregulatory control of human skin blood flow,.\n                           J AppI Physiol 1986, 61: 1613\u20131622.","journal-title":"J AppI Physiol"},{"key":"4_CR24","first-page":"133","volume":"16","author":"P Svedman","year":"1982","unstructured":"Svedman P, Holmberg J, Jacobson S, Lindell SE, Ponnert L: On the relation between transcutaneous oxygen tension and skin blood flow, Scand.\n                           J Reconstr Surg 1982, 16: 133\u2013141.","journal-title":"J Reconstr Surg"},{"key":"4_CR25","doi-asserted-by":"publisher","first-page":"761","DOI":"10.3109\/00365518009095593","volume":"40","author":"J Eickhoff","year":"1980","unstructured":"Eickhoff J, Jacobsen E: Correlation of transcutaneous oxygen tension to blood flow in heated skin, Scand.\n                           J Clin Lab Invest 1980, 40: 761\u2013767.","journal-title":"J Clin Lab Invest"},{"key":"4_CR26","doi-asserted-by":"publisher","first-page":"419","DOI":"10.1097\/00000637-198805000-00004","volume":"20","author":"A Orenstein","year":"1988","unstructured":"Orenstein A, Mazkereth R, Tsur H: Mapping of the human body skin with the transcutaneous oxygen pressure method,.\n                           Ann Plast Surg 1988, 20: 419\u2013432.","journal-title":"Ann Plast Surg"},{"key":"4_CR27","doi-asserted-by":"publisher","first-page":"243","DOI":"10.1111\/j.1365-2133.1991.tb14748.x","volume":"125","author":"H Takiwaki","year":"1991","unstructured":"Takiwaki H, Nakanishi H, Shono Y, Arase S: The influence of cutaneous factors on the transcutaneous pO\n                           \n                              2\n                           \n                           and pCO\n                           \n                              2\n                           \n                           at various body sites,.\n                           Br J Dermatol 1991, 125: 243\u2013252.","journal-title":"Br J Dermatol"},{"key":"4_CR28","first-page":"17","volume":"48(Suppl.189)","author":"P Jaszczac","year":"1988","unstructured":"Jaszczac P, Sejrsen P, Sorensen PR: The influence of epidermal membrane on percutaneous pO\n                           \n                              2\n                           \n                           and metabolic rate, Scand.\n                           J Clin Invest 1988, 48(Suppl.189): 17\u201324.","journal-title":"J Clin Invest"},{"key":"4_CR29","first-page":"235","volume":"24:4","author":"J Dooley","year":"1997","unstructured":"Dooley J, King G, Slade B: Establishment of reference pressure of transcutaneous oxygen for the comparative evaluation of problem wounds,.\n                           Undersea Hyperb Med 1997, 24:4: 235\u201344.","journal-title":"Undersea Hyperb Med"},{"key":"4_CR30","first-page":"175","volume":"24:3","author":"WA Zamborni","year":"1997","unstructured":"Zamborni WA, Wong HP, Stephenson LL, Pfeifer MA: Evaluation of hyperbaric oxygen for diabetic wounds: a prospective study,.\n                           Undersea Hyperb Med 1997, 24:3: 175\u20139.","journal-title":"Undersea Hyperb Med"},{"key":"4_CR31","first-page":"186","volume":"3","author":"J Alves","year":"1997","unstructured":"Alves J, Pinto P, Fernandes AP, Abrunhosa S, Panarra A, Galego N, Soromenho F, Riscado MV, Rodrigues L: Quantitative assessment of Sistemic Lupus Changes by non-invasive techniques,.\n                           Skin Res Technol 1997, 3: 186.","journal-title":"Skin Res Technol"},{"key":"4_CR32","doi-asserted-by":"publisher","first-page":"147","DOI":"10.2337\/diacare.22.1.147","volume":"22","author":"M Kalani","year":"1999","unstructured":"Kalani M, Brismar K, Fagrell B, Ostergren J, Jorneskog G: Transcutaneous oxygen tension and toe blood pressure as predictors for outcome of diabetic foot ulcers,.\n                           Diab Care 1999, 22: 147\u2013151.","journal-title":"Diab Care"},{"key":"4_CR33","first-page":"569","volume":"89","author":"GE Bone","year":"1981","unstructured":"Bone GE, Pomajzl MJ: The blood pressure by photoplethysmography: an index of healing in forefoot amputation,.\n                           Surgery 1981, 89: 569\u2013574.","journal-title":"Surgery"},{"issue":"2","key":"4_CR34","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1177\/000331979204300210","volume":"43","author":"CE Slagsvold","year":"1992","unstructured":"Slagsvold CE, Stranden E, Rosen L, Kroese AJ: The role ofr blood perfusion and tissue oxygenation in the postischemic transcutaneous pO\n                           \n                              2\n                           \n                           response,.\n                           Angiology 1992,43(2):155\u2013162.","journal-title":"Angiology"},{"key":"4_CR35","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1111\/j.1600-0536.1994.tb00565.x","volume":"30","author":"A Bircher","year":"1994","unstructured":"Bircher A, de Boer E, Agner T, Wahlberg JE, Serup J: Guidelines for measurement of cutaneous blood flow by laser doppler flowmetry. A report from the standardisation group of the European Society of Contact dermatitis,.\n                           Cont Dermatitis 1994, 30: 65\u201372.","journal-title":"Cont Dermatitis"},{"key":"4_CR36","first-page":"172","volume":"6","author":"A Leal","year":"2000","unstructured":"Leal A, Alves J, Rodrigues L: Usefulness of Transcutaneous Indicators as Predictors of Peripheral Dysfunction, Abst. 13th International Congress of the ISBS,.\n                           Skin Res & Technol 2000, 6: 172\u2013173.","journal-title":"Skin Res & Technol"},{"key":"4_CR37","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1016\/0026-2862(89)90069-1","volume":"37","author":"L Bernardi","year":"1989","unstructured":"Bernardi L, Rossi M, Fratino P, Finardi G, Mevio E, Orlandi C: Relationship between changes in human skin blood flow and autonomic tone,.\n                           Microvasc Res 1989, 37: 16\u201327. 10.1016\/0026-2862(89)90069-1","journal-title":"Microvasc Res"},{"key":"4_CR38","first-page":"133","volume-title":"in \"Bioengineering of the Skin : Cutaneous Blood Flow and Erythema\", Berardesca, E., Elsner, P., Maibach H., Eds., CRC Press, Boca Raton,","author":"E Tur","year":"1995","unstructured":"Tur E: Cutaneous laser doppler flowmetry in general medicine,.\n                           in \"Bioengineering of the Skin : Cutaneous Blood Flow and Erythema\", Berardesca, E., Elsner, P., Maibach H., Eds., CRC Press, Boca Raton, 1995, 133\u2013153."},{"key":"4_CR39","doi-asserted-by":"publisher","first-page":"1503","DOI":"10.1001\/archderm.123.11.1503","volume":"123","author":"JK Wilkin","year":"1987","unstructured":"Wilkin JK, Troter K: Cognitive activity and cutaneous blood flow, Arch.\n                           Dermatol 1987, 123: 1503. 10.1001\/archderm.123.11.1503","journal-title":"Dermatol"},{"key":"4_CR40","doi-asserted-by":"publisher","first-page":"442","DOI":"10.1111\/1523-1747.ep12522619","volume":"81","author":"E Tur","year":"1983","unstructured":"Tur E, Tur M, Maibach H, Guy R: Basal perfusion of the cutaneous microcirculation : measurements as a function of anatomical position,.\n                           J Inv Dermatol 1983, 81: 442\u2013446.","journal-title":"J Inv Dermatol"},{"key":"4_CR41","first-page":"105","volume-title":"in \"Aging Skin : Properties and Functional Changes\", Leveque, JL & Agache, P., edst.. Marcel Dekker ed., NY,","author":"A Bircher","year":"1993","unstructured":"Bircher A, Roskos K, Maibach H, Guy R: Laser doppler measured cutaneous blood flow: effects with age,.\n                           in \"Aging Skin : Properties and Functional Changes\", Leveque, JL & Agache, P., edst.. Marcel Dekker ed., NY, 1993, 105\u2013121."},{"key":"4_CR42","doi-asserted-by":"publisher","first-page":"787","DOI":"10.1111\/j.1365-2133.1989.tb01376.x","volume":"120","author":"E Berardesca","year":"1989","unstructured":"Berardesca E, Maibach H: Cutaneous reactive hyperemia: recial differences induced by corticoid application,.\n                           Brit J Dermatol 1989, 120: 787\u2013794.","journal-title":"Brit J Dermatol"},{"key":"4_CR43","doi-asserted-by":"publisher","first-page":"944","DOI":"10.1111\/j.1365-2044.1982.tb01859.x","volume":"37","author":"HR Goldman","year":"1982","unstructured":"Goldman HR, Gribbin RJ, Martin L: Transcutaneous pCO\n                           \n                              2\n                           \n                           in adults,.\n                           Anaesthesia 1982, 37: 944\u2013946.","journal-title":"Anaesthesia"},{"key":"4_CR44","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1515\/jpme.1983.11.1.51","volume":"11","author":"O Lofgren","year":"1983","unstructured":"Lofgren O, Anderson D: Simultaneous transcutaneous carbon dioxide and transcutaneous oxygen monitoring in neonatal intensive care,.\n                           J Perinat Med 1983, 11: 121\u2013134.","journal-title":"J Perinat Med"}],"container-title":["BMC Dermatology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-5945-1-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/1471-5945-1-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-5945-1-4","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-5945-1-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,13]],"date-time":"2024-09-13T16:46:38Z","timestamp":1726245998000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcdermatol.biomedcentral.com\/articles\/10.1186\/1471-5945-1-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,8,20]]},"references-count":44,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2001,12]]}},"alternative-id":["4"],"URL":"https:\/\/doi.org\/10.1186\/1471-5945-1-4","relation":{},"ISSN":["1471-5945"],"issn-type":[{"value":"1471-5945","type":"electronic"}],"subject":[],"published":{"date-parts":[[2001,8,20]]},"assertion":[{"value":"2 May 2001","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 August 2001","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 August 2001","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}],"article-number":"4"}}