{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T10:30:05Z","timestamp":1773311405960,"version":"3.50.1"},"reference-count":38,"publisher":"Springer Science and Business Media LLC","issue":"1","content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Malar J"],"published-print":{"date-parts":[[2010,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:sec>\n            <jats:title>Background<\/jats:title>\n            <jats:p>\n              <jats:italic>Plasmodium falciparum<\/jats:italic> is the major species responsible for malaria transmission on the island of Pr\u00edncipe, in the Republic of S\u00e3o Tom\u00e9 and Pr\u00edncipe (STP). Indoor residual spraying (IRS) has been intensively deployed on the island, since 2003. Other measures included intermittent preventive therapy (IPT), since 2004, as well as artemisinin-based therapy (ACT) and long-lasting insecticidal nets (LLINs) from 2005. The work was coordinated by the Ministry of Health of STP through their Centro Nacional de Endemias (CNE) and the impact of such an integrated control programme on the prevalence and epidemiology of malaria in Pr\u00edncipe was evaluated.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods<\/jats:title>\n            <jats:p>The scaling-up of preventive strategies included IRS, LLINs, IPT for pregnant women, as well as early diagnosis and prompt treatment with ACT. Regular implementation of an island-wide IRS programme was carried out yearly in 2003-2005, and later in 2008. Malaria incidence and prevalence were estimated based on passive case detection and active case detection, respectively. Slide positivity rate (SPR) was used as an indicator of any increase of malaria cases during and after the control programme was initiated.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>Regular IRS achieved a coverage of 85-90% for each of the four annual cycles (2003-2005, annually and one spraying in 2008) while usage of LLINs was never superior to 50% from 2006-2009. Coverage of IPT steadily increased from 50% in 2004 to 80% in 2008. Since 2006, over 90% of uncomplicated malaria patients received ACT treatment. Severe malaria cases were hospitalized and treated with quinine. Monthly trends of SPR were constantly over 50% in 2003, but steadily decreased below 10% in 2006. SPR has been below 5% since 2007, but an increase to up to 15% was noted in June 2009 when 16 imported cases were detected. A steep decline by 99% of malaria incidence was observed between 2003 and 2008, with an incidence risk of the population of five per thousand, in 2008. No malaria mortality has been reported since 2005. Species shift from falciparum to non-falciparum malaria was noted after a five-year intensive control programme. Cross-sectional country-wide active surveillances showed malaria prevalences of 1.1%, 0.7%, and 0.9% in June 2006, Oct 2007, and July 2009, respectively, of which over 90% were asymptomatic.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusion<\/jats:title>\n            <jats:p>The effective measures of the combination of four major control methods have produced a rapid decline in malaria morbidity and mortality on the island of Pr\u00edncipe. The combination of IRS, IPT, and active surveillance with ACT treatment seemed to have played important roles to achieve a present status of low and stable malaria on the island. In low transmission settings, any increase of malaria morbidity indicates potential epidemics and assumes that current control strategies were interrupted. Active surveillance should be reinforced to follow and monitor all asymptomatic carriers and imported cases. Consolidation and a shift to elimination phase demands the sustainability of such integrated programmes.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1186\/1475-2875-9-26","type":"journal-article","created":{"date-parts":[[2010,1,20]],"date-time":"2010-01-20T19:28:40Z","timestamp":1264015720000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":51,"title":["Pre-elimination of malaria on the island of Pr\u00edncipe"],"prefix":"10.1186","volume":"9","author":[{"given":"Pei-Wen","family":"Lee","sequence":"first","affiliation":[]},{"given":"Chia-Tai","family":"Liu","sequence":"additional","affiliation":[]},{"given":"Herodes Sacramento","family":"Rampao","sequence":"additional","affiliation":[]},{"given":"Virgilio E","family":"do Rosario","sequence":"additional","affiliation":[]},{"given":"Men-Fang","family":"Shaio","sequence":"additional","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2010,1,20]]},"reference":[{"key":"1107_CR1","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1016\/S0001-706X(00)00100-5","volume":"76","author":"J Pinto","year":"2000","unstructured":"Pinto J, Sousa CA, Gil V, Ferreira C, Goncalves L, Lopes D, Petrarca V, Charlwood JD, do Rosario VE: Malaria in S\u00e3o Tom\u00e9 and Pr\u00edncipe: parasite prevalences and vector densities. Acta Trop. 2000, 76: 185-193. 10.1016\/S0001-706X(00)00100-5.","journal-title":"Acta Trop"},{"key":"1107_CR2","first-page":"142","volume-title":"Malaria in S\u00e3o Tom\u00e9 and Pr\u00edncipe. Proceedings of the Conference on Malaria in Africa","author":"JGV Ceita","year":"1986","unstructured":"Ceita JGV: Malaria in S\u00e3o Tom\u00e9 and Pr\u00edncipe. Proceedings of the Conference on Malaria in Africa. Edited by: Buck AA. 1986, Washington DC, American Institute of Biological Sciences, 142-155."},{"key":"1107_CR3","doi-asserted-by":"crossref","first-page":"248","DOI":"10.4269\/ajtmh.2008.78.248","volume":"78","author":"LF Tseng","year":"2008","unstructured":"Tseng LF, Chang WC, Ferreira MC, Wu CH, Rampao HS, Lien JC: Rapid control of malaria by means of indoor residual spraying of alphacypermethrin in the Democratic Republic of S\u00e3o Tom\u00e9 and Pr\u00edncipe. Am J Trop Med Hyg. 2008, 78: 248-250.","journal-title":"Am J Trop Med Hyg"},{"key":"1107_CR4","doi-asserted-by":"crossref","first-page":"133","DOI":"10.4269\/ajtmh.2009.80.133","volume":"80","author":"HD Teklehaimanot","year":"2009","unstructured":"Teklehaimanot HD, Teklehaimanot A, Kiszewski A, Rampao HS, Sachs JD: Malaria in S\u00e3o Tom\u00e9 and Pr\u00edncipe: on the brink of elimination after three years of effective antimalarial measures. Am J Trop Med Hyg. 2009, 80: 133-140.","journal-title":"Am J Trop Med Hyg"},{"key":"1107_CR5","volume-title":"IV Encontro de Medicina Tropical dos Paises de Lingua Portuguesa e XLV Congresso da Sociedade Brasileira de Medicina Tropical","author":"MF Shaio","year":"2009","unstructured":"Shaio MF: Um programa bem sucedido de controle da malaria na Africa. IV Encontro de Medicina Tropical dos Paises de Lingua Portuguesa e XLV Congresso da Sociedade Brasileira de Medicina Tropical. 2009"},{"key":"1107_CR6","volume-title":"World malaria report","author":"World Health Organization","year":"2005","unstructured":"World Health Organization: World malaria report. 2005, Geneva, World Health Organization"},{"key":"1107_CR7","volume-title":"Distribuicao Espacial da Populacao S\u00e3o Tomense, 2001-2010","author":"Instituto Nacional de Estatistica","year":"2008","unstructured":"Instituto Nacional de Estatistica: Distribuicao Espacial da Populacao S\u00e3o Tomense, 2001-2010. 2008, S\u00e3o Tom\u00e9 and Pr\u00edncipe: Ministerio de Plano e Financas, Instituto Nacional de Estatistica"},{"key":"1107_CR8","volume-title":"Report of the WHO informal consultation on test procedures for insecticide resistance monitoring in malaria vectors, bio-efficacy and persistence of insecticides on treated surfaces","author":"World Health Organization","year":"1998","unstructured":"World Health Organization: Report of the WHO informal consultation on test procedures for insecticide resistance monitoring in malaria vectors, bio-efficacy and persistence of insecticides on treated surfaces. 1998, Geneva, World Health Organization"},{"key":"1107_CR9","volume-title":"World malaria report","author":"World Health Organization","year":"2008","unstructured":"World Health Organization: World malaria report. 2008, Geneva, World Health Organization"},{"key":"1107_CR10","volume-title":"Manual on practical entomology in malaria. Part II","author":"World Health Organization","year":"1975","unstructured":"World Health Organization: Manual on practical entomology in malaria. Part II. 1975, Geneva, World Health Organization"},{"key":"1107_CR11","doi-asserted-by":"publisher","first-page":"300","DOI":"10.1093\/jee\/64.1.300","volume":"64","author":"MS Mulla","year":"1971","unstructured":"Mulla MS, Norland RL, Fanara DM, Darwazeh A, McKean D: Control of chironomid midges in recreational lakes. J Econ Entomol. 1971, 64: 300-307.","journal-title":"J Econ Entomol"},{"key":"1107_CR12","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1016\/0001-706X(95)00101-J","volume":"60","author":"A Kroeger","year":"1995","unstructured":"Kroeger A, Horstick O, Riedl C, Kaiser A, Becker N: The potential for malaria control with the biological larvicide Bacillus thuringiensis israelensis (Bti) in Peru and Ecuador. Acta Trop. 1995, 60: 47-57. 10.1016\/0001-706X(95)00101-J.","journal-title":"Acta Trop"},{"key":"1107_CR13","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1046\/j.1365-3156.2003.00979.x","volume":"8","author":"U Fillinger","year":"2003","unstructured":"Fillinger U, Knols BGJ, Becker N: Efficacy and efficiency of new Bacillus thuringiensis var. israelensis and Bacillus sphaericus formulations against Afrotropical anophelines in Western Kenya. Trop Med Int Health. 2003, 8: 37-47. 10.1046\/j.1365-3156.2003.00979.x.","journal-title":"Trop Med Int Health"},{"key":"1107_CR14","volume-title":"National Strategic Plan for Roll Back Malaria in S\u00e3o Tom\u00e9 and Pr\u00edncipe, 2004-2010","author":"Centro National de Endemias","year":"2004","unstructured":"Centro National de Endemias: National Strategic Plan for Roll Back Malaria in S\u00e3o Tom\u00e9 and Pr\u00edncipe, 2004-2010. 2004, S\u00e3o Tom\u00e9 and Pr\u00edncipe: Ministerio da Saude, Centro Nacional de Endemias"},{"key":"1107_CR15","volume-title":"Programa de Saude Reprodutiva 2004-2008","author":"Direccao dos Cuidados de Saude","year":"2008","unstructured":"Direccao dos Cuidados de Saude: Programa de Saude Reprodutiva 2004-2008. 2008, S\u00e3o Tom\u00e9 and Pr\u00edncipe: Ministerio da Saude, Direccao dos Cuidados de Saude"},{"key":"1107_CR16","volume-title":"Avaliacao do Conhecimento, Atitude e Pratica da Populacao em Relacao ao Mosquiteiro (Fundo Global)","author":"Centro National de Endemias","year":"2008","unstructured":"Centro National de Endemias: Avaliacao do Conhecimento, Atitude e Pratica da Populacao em Relacao ao Mosquiteiro (Fundo Global). 2008, S\u00e3o Tom\u00e9 and Pr\u00edncipe: Ministerio da Saude, Centro Nacional de Endemias"},{"key":"1107_CR17","doi-asserted-by":"publisher","first-page":"315","DOI":"10.1016\/0166-6851(93)90077-B","volume":"61","author":"G Snounou","year":"1993","unstructured":"Snounou G, Viriyakosol S, Zhu XP, Jarra W, Pinheiro L, Rosario VE, Thaithong S, Brown KN: High sensitivity of detection of human malaria parasites by the use of nested polymerase chain reaction. Mol Biochem Parasitol. 1993, 61: 315-320. 10.1016\/0166-6851(93)90077-B.","journal-title":"Mol Biochem Parasitol"},{"key":"1107_CR18","doi-asserted-by":"publisher","first-page":"e309","DOI":"10.1371\/journal.pmed.0040309","volume":"4","author":"A Bhattarao","year":"2007","unstructured":"Bhattarao A, Ali AS, Kachur SP, Martensson A, Abbas AK, Khatib R, Al-Mafazy A, Ramsan M, Rotllant g, Gerstenmaier JF, Molteni F, Abdulla S, Montgomery SM, Kaneko A, Bjorkman A: Impact of artemisinin-based combination therapy and insecticide-treated nets on malaria burden in Zanzibar. PLoS Med. 2007, 4: e309-10.1371\/journal.pmed.0040309.","journal-title":"PLoS Med"},{"key":"1107_CR19","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.4269\/ajtmh.2007.76.1027","volume":"76","author":"I Kleinschmidt","year":"2007","unstructured":"Kleinschmidt I, Torrez M, Schwabe C, Benavente L, Seocharar I, Jituboh D, Nseng G, Sharp B: Factors influencing the effectiveness of malaria control in Bioko island, Equatorial Guinea. Am J Trop Med Hyg. 2007, 76: 1027-1032.","journal-title":"Am J Trop Med Hyg"},{"key":"1107_CR20","doi-asserted-by":"crossref","first-page":"519","DOI":"10.4269\/ajtmh.2009.81.519","volume":"81","author":"I Kleinschmidt","year":"2009","unstructured":"Kleinschmidt I, Schwabe C, Shiva M, Segura JL, Sima V, Mabunda SJ, Coleman M: Combining indoor residual spraying and insecticide-treated net interventions. Am J Trop Med Hyg. 2009, 81: 519-524.","journal-title":"Am J Trop Med Hyg"},{"key":"1107_CR21","doi-asserted-by":"publisher","first-page":"1035","DOI":"10.1016\/S0140-6736(07)61477-9","volume":"370","author":"GW Fegan","year":"2007","unstructured":"Fegan GW, Noor AM, Akhwale WS, Cousens S, Snow RW: Effect of expanded insecticide-treated bednet coverage on child survival in rural Kenya: a longitudinal study. Lancet. 2007, 370: 1035-1039. 10.1016\/S0140-6736(07)61477-9.","journal-title":"Lancet"},{"key":"1107_CR22","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1186\/1475-2875-5-33","volume":"5","author":"PM Nyarango","year":"2006","unstructured":"Nyarango PM, Gebremeskel T, Mebrahtu G, Mufunda J, Abdulmumini U, Ogbamariam A, Kosia A, Gebremichael A, Gunawardena D, Ghebrat Y, Okbaldet Y: A steep decline of malaria morbidity and mortality trends in Eritrea between 2000 and 2004: the effect of combination of control methods. Malar J. 2006, 5: 33-10.1186\/1475-2875-5-33.","journal-title":"Malar J"},{"key":"1107_CR23","doi-asserted-by":"publisher","first-page":"158","DOI":"10.1186\/1475-2875-6-158","volume":"6","author":"N Protopopoff","year":"2007","unstructured":"Protopopoff N, Van Bortel W, Macrotty T, Van Herp M, Maes P, Baza D, D'Alessandro U, Coosemans M: Spatial targeted vector control in the highlands of Burundi and its impact on malaria transmission. Malar J. 2007, 6: 158-10.1186\/1475-2875-6-158.","journal-title":"Malar J"},{"key":"1107_CR24","doi-asserted-by":"crossref","first-page":"12","DOI":"10.4269\/ajtmh.2008.79.12","volume":"79","author":"N Protopopoff","year":"2008","unstructured":"Protopopoff N, Van Bortel W, Macrotty T, Van Herp M, Maes P, Baza D, D'Alessandro U, Coosemans M: Spatial targeted vector control is able to reduce malaria prevalence in the highlands of Burundi. Am J Trop Med Hyg. 2008, 79: 12-18.","journal-title":"Am J Trop Med Hyg"},{"key":"1107_CR25","doi-asserted-by":"crossref","first-page":"2569","DOI":"10.1371\/journal.pcbi.0030255","volume":"3","author":"JA Filipe","year":"2007","unstructured":"Filipe JA, Riley EM, Drakeley CJ, Sutherland CJ, Ghani AC: Determination of the processes driving the acquisition of immunity to malaria using a mathematical transmission model. PLoS Computational Biol. 2007, 3: 2569-2579.","journal-title":"PLoS Computational Biol"},{"key":"1107_CR26","doi-asserted-by":"publisher","first-page":"e4383","DOI":"10.1371\/journal.pone.0004383","volume":"4","author":"AC Ghani","year":"2009","unstructured":"Ghani AC, Sutherland CJ, Riley EM, Drakeley CJ, Griffin JT, Gosling RD, Filipe JAN: Loss of population levels of immunity to malaria as a result of exposure-reducing interventions: Consequences for interpretation of disease trends. PLoS ONE. 2009, 4: e4383-10.1371\/journal.pone.0004383.","journal-title":"PLoS ONE"},{"issue":"suppl 6","key":"1107_CR27","doi-asserted-by":"crossref","first-page":"14","DOI":"10.4269\/ajtmh.77.6.suppl.14","volume":"77","author":"SJ Rogerson","year":"2007","unstructured":"Rogerson SJ, Mwapasa V, Meshnick SR: Malaria in pregnancy: linking immunity and pathogenesis to prevention. Am J Trop Med Hyg. 2007, 77 (suppl 6): 14-22.","journal-title":"Am J Trop Med Hyg"},{"key":"1107_CR28","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1186\/1475-2875-4-27","volume":"4","author":"O Branch","year":"2005","unstructured":"Branch O, Casapia WM, Gamboa DV, Hernandez JN, Alava FF, Roncal N, Alvarez E, Perez EJ, Gotuzzo E: Clustered local transmission and asymptomatic Plasmodium falciparum and Plasmodium vivax malaria infections in a recently emerged, hypoendemic Peruvian Amazon community. Malar J. 2005, 4: 27-10.1186\/1475-2875-4-27.","journal-title":"Malar J"},{"issue":"suppl 1","key":"1107_CR29","doi-asserted-by":"publisher","first-page":"S11","DOI":"10.1186\/1475-2875-7-S1-S11","volume":"7","author":"A Mills","year":"2008","unstructured":"Mills A, Lubell Y, Hanson K: Malaria eradication: the economic, financial and institutional challenge. Malar J. 2008, 7 (suppl 1): S11-10.1186\/1475-2875-7-S1-S11.","journal-title":"Malar J"},{"key":"1107_CR30","doi-asserted-by":"publisher","first-page":"256","DOI":"10.1016\/S0035-9203(00)90311-0","volume":"94","author":"J Pinto","year":"2000","unstructured":"Pinto J, Sousa CA, Gil V, Goncalves L, Lopes D, do Rosario VE, Charlwood JD: Mixed-species malaria infections in the human population of S\u00e3o Tom\u00e9 island, West Africa. Trans R Soc Trop Med Hyg. 2000, 94: 256-257. 10.1016\/S0035-9203(00)90311-0.","journal-title":"Trans R Soc Trop Med Hyg"},{"issue":"suppl 1","key":"1107_CR31","doi-asserted-by":"publisher","first-page":"S8","DOI":"10.1186\/1475-2875-7-S1-S8","volume":"7","author":"NJ White","year":"2008","unstructured":"White NJ: The role of anti-malarial drugs in eliminating malaria. Malar J. 2008, 7 (suppl 1): S8-10.1186\/1475-2875-7-S1-S8.","journal-title":"Malar J"},{"key":"1107_CR32","volume-title":"Guidelines on the elimination of residual foci of malaria transmission. EMRO technical publications series 33","author":"World Health Organization","year":"2007","unstructured":"World Health Organization: Guidelines on the elimination of residual foci of malaria transmission. EMRO technical publications series 33. 2007, Geneva, World Health Organization"},{"key":"1107_CR33","doi-asserted-by":"publisher","first-page":"271","DOI":"10.1016\/S1471-4922(03)00116-8","volume":"19","author":"MC Bruce","year":"2003","unstructured":"Bruce MC, Day KP: Cross-species regulation of Plasmodium parasitemia in semi-immune children from Papua New Guinea. Trends Parasitol. 2003, 19: 271-277. 10.1016\/S1471-4922(03)00116-8.","journal-title":"Trends Parasitol"},{"key":"1107_CR34","doi-asserted-by":"publisher","first-page":"1266","DOI":"10.1172\/JCI33996","volume":"118","author":"BM Greenwood","year":"2008","unstructured":"Greenwood BM, Fidock DA, Kyle DE, Kappe SHI, Alonso PL, Collins FH, Duffy PE: Malaria: progress, perils, and prospects for eradication. J Clin Invest. 2008, 118: 1266-1276. 10.1172\/JCI33996.","journal-title":"J Clin Invest"},{"key":"1107_CR35","doi-asserted-by":"publisher","first-page":"e1243","DOI":"10.1371\/journal.pone.0001243","volume":"2","author":"J Pinto","year":"2007","unstructured":"Pinto J, Lynd A, Vicente JL, Santolamazza F, Randle NP, Gentile G, Moreno M, Simard F, Charlwood JD, do Rosario VE, Caccone A, della Torre A, Donnelly MJ: Multiple origins of knowckdown resistance mutations in the afrotropical mosquito vector Anopheles gambiae. PLoS ONE. 2007, 2: e1243-10.1371\/journal.pone.0001243.","journal-title":"PLoS ONE"},{"key":"1107_CR36","doi-asserted-by":"publisher","first-page":"207","DOI":"10.1016\/j.actatropica.2007.01.005","volume":"101","author":"V Corbel","year":"2007","unstructured":"Corbel V, N'Guessan R, Brengues C, Chandre F, Djogbenou L, Martin T, Akogbeto M, Hougard JM, Rowland M: Multiple insecticide resistance mechanisms in Anopheles gambiae and Culex quinquefasiatus from Benin, West Africa. Acta Trop. 2007, 101: 207-216. 10.1016\/j.actatropica.2007.01.005.","journal-title":"Acta Trop"},{"key":"1107_CR37","doi-asserted-by":"publisher","first-page":"199","DOI":"10.3201\/eid1302.060631","volume":"13","author":"R N'Guessan","year":"2007","unstructured":"N'Guessan R, Corbel V, Akogbeto M, Rowland M: Reduced efficacy of insecticide-treated nets and indoor residual spraying for malaria control in pyrethroid resistance areas, Benin. Emerg Infect Dis. 2007, 13: 199-206. 10.3201\/eid1302.060631.","journal-title":"Emerg Infect Dis"},{"key":"1107_CR38","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1186\/1475-2875-2-15","volume":"2","author":"R Hagmann","year":"2003","unstructured":"Hagmann R, Charlwood JD, Gil V, Ferreira C, Rosario V, Smith TA: Malaria and its possible control on the island of Pr\u00edncipe. Malar J. 2003, 2: 15-10.1186\/1475-2875-2-15.","journal-title":"Malar J"}],"container-title":["Malaria Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/1475-2875-9-26.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T05:53:47Z","timestamp":1630475627000},"score":1,"resource":{"primary":{"URL":"https:\/\/malariajournal.biomedcentral.com\/articles\/10.1186\/1475-2875-9-26"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,1,20]]},"references-count":38,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2010,12]]}},"alternative-id":["1107"],"URL":"https:\/\/doi.org\/10.1186\/1475-2875-9-26","relation":{},"ISSN":["1475-2875"],"issn-type":[{"value":"1475-2875","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,1,20]]},"assertion":[{"value":"9 September 2009","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 January 2010","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 January 2010","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}],"article-number":"26"}}