{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T06:51:19Z","timestamp":1771483879798,"version":"3.50.1"},"reference-count":79,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,2,12]],"date-time":"2025-02-12T00:00:00Z","timestamp":1739318400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2025,2,12]],"date-time":"2025-02-12T00:00:00Z","timestamp":1739318400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"funder":[{"DOI":"10.13039\/501100004837","name":"Ministerio de Ciencia e Innovaci\u00f3n","doi-asserted-by":"publisher","award":["PID2021-124407NB-I00"],"award-info":[{"award-number":["PID2021-124407NB-I00"]}],"id":[{"id":"10.13039\/501100004837","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004837","name":"Ministerio de Ciencia e Innovaci\u00f3n","doi-asserted-by":"publisher","award":["PID2021-124407NB-I00"],"award-info":[{"award-number":["PID2021-124407NB-I00"]}],"id":[{"id":"10.13039\/501100004837","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004593","name":"Universidad Aut\u00f3noma de Madrid","doi-asserted-by":"publisher","award":["CA1\/RSUE\/2021-00801"],"award-info":[{"award-number":["CA1\/RSUE\/2021-00801"]}],"id":[{"id":"10.13039\/501100004593","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Portuguese Science Foundation","award":["SFRH\/BD\/139561\/2018"],"award-info":[{"award-number":["SFRH\/BD\/139561\/2018"]}]},{"name":"Portuguese Science Foundation","award":["SFRH\/BD\/139561\/2018"],"award-info":[{"award-number":["SFRH\/BD\/139561\/2018"]}]},{"name":"Portuguese Science Foundation","award":["SFRH\/BD\/139561\/2018"],"award-info":[{"award-number":["SFRH\/BD\/139561\/2018"]}]},{"name":"Portuguese Science Foundation","award":["SFRH\/BD\/139561\/2018"],"award-info":[{"award-number":["SFRH\/BD\/139561\/2018"]}]},{"name":"Portuguese Science Foundation","award":["COVID\/BD\/153268\/2023"],"award-info":[{"award-number":["COVID\/BD\/153268\/2023"]}]},{"name":"Portuguese Science Foundation","award":["SFRH\/BD\/139561\/2018"],"award-info":[{"award-number":["SFRH\/BD\/139561\/2018"]}]},{"name":"Portuguese Science Foundation","award":["COVID\/BD\/153268\/2023"],"award-info":[{"award-number":["COVID\/BD\/153268\/2023"]}]},{"name":"Portuguese Science Foundation","award":["SFRH\/BD\/139561\/2018"],"award-info":[{"award-number":["SFRH\/BD\/139561\/2018"]}]},{"name":"Portuguese Science Foundation","award":["SFRH\/BD\/139561\/2018"],"award-info":[{"award-number":["SFRH\/BD\/139561\/2018"]}]},{"name":"LARSyS","award":["10.54499\/LA\/P\/0083\/2020"],"award-info":[{"award-number":["10.54499\/LA\/P\/0083\/2020"]}]},{"name":"LARSyS","award":["10.54499\/LA\/P\/0083\/2020"],"award-info":[{"award-number":["10.54499\/LA\/P\/0083\/2020"]}]},{"name":"LARSyS","award":["10.54499\/LA\/P\/0083\/2020"],"award-info":[{"award-number":["10.54499\/LA\/P\/0083\/2020"]}]},{"name":"LARSyS","award":["10.54499\/LA\/P\/0083\/2020"],"award-info":[{"award-number":["10.54499\/LA\/P\/0083\/2020"]}]},{"name":"LARSyS","award":["10.54499\/LA\/P\/0083\/2020"],"award-info":[{"award-number":["10.54499\/LA\/P\/0083\/2020"]}]},{"name":"LARSyS","award":["10.54499\/LA\/P\/0083\/2020"],"award-info":[{"award-number":["10.54499\/LA\/P\/0083\/2020"]}]},{"name":"Programa Operacional Regional de Lisboa 2020","award":["LISBOA-01-0145-FEDER-029675"],"award-info":[{"award-number":["LISBOA-01-0145-FEDER-029675"]}]},{"name":"Programa Operacional Regional de Lisboa 2020","award":["LISBOA-01-0145-FEDER-029675"],"award-info":[{"award-number":["LISBOA-01-0145-FEDER-029675"]}]},{"name":"Programa Operacional Regional de Lisboa 2020","award":["LISBOA-01-0145-FEDER-029675"],"award-info":[{"award-number":["LISBOA-01-0145-FEDER-029675"]}]},{"name":"Programa Operacional Regional de Lisboa 2020","award":["LISBOA-01-0145-FEDER-029675"],"award-info":[{"award-number":["LISBOA-01-0145-FEDER-029675"]}]},{"name":"Programa Operacional Regional de Lisboa 2020","award":["LISBOA-01-0145-FEDER-029675"],"award-info":[{"award-number":["LISBOA-01-0145-FEDER-029675"]}]},{"name":"Programa Operacional Regional de Lisboa 2020","award":["LISBOA-01-0145-FEDER-029675"],"award-info":[{"award-number":["LISBOA-01-0145-FEDER-029675"]}]},{"name":"Programa Operacional Regional de Lisboa 2020","award":["LISBOA-01-0145-FEDER-029675"],"award-info":[{"award-number":["LISBOA-01-0145-FEDER-029675"]}]},{"name":"Programa Operacional Regional de Lisboa 2020","award":["LISBOA-01-0145-FEDER-029675"],"award-info":[{"award-number":["LISBOA-01-0145-FEDER-029675"]}]},{"name":"Programa Operacional Regional de Lisboa 2020","award":["LISBOA-01-0145-FEDER-029675"],"award-info":[{"award-number":["LISBOA-01-0145-FEDER-029675"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Headache Pain"],"DOI":"10.1186\/s10194-025-01970-z","type":"journal-article","created":{"date-parts":[[2025,2,12]],"date-time":"2025-02-12T07:54:21Z","timestamp":1739346861000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["White matter alterations in episodic migraine without aura patients assessed with diffusion MRI: effect of free water correction"],"prefix":"10.1186","volume":"26","author":[{"given":"Irene","family":"Guadilla","sequence":"first","affiliation":[]},{"given":"Ana R","family":"Fouto","sequence":"additional","affiliation":[]},{"given":"Amparo","family":"Ruiz-Tagle","sequence":"additional","affiliation":[]},{"given":"In\u00eas","family":"Esteves","sequence":"additional","affiliation":[]},{"given":"Gina","family":"Caetano","sequence":"additional","affiliation":[]},{"given":"Nuno A","family":"Silva","sequence":"additional","affiliation":[]},{"given":"Pedro","family":"Vilela","sequence":"additional","affiliation":[]},{"given":"Raquel","family":"Gil-Gouveia","sequence":"additional","affiliation":[]},{"given":"Santiago","family":"Aja-Fern\u00e1ndez","sequence":"additional","affiliation":[]},{"given":"Patr\u00edcia","family":"Figueiredo","sequence":"additional","affiliation":[]},{"given":"Rita G","family":"Nunes","sequence":"additional","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2025,2,12]]},"reference":[{"key":"1970_CR1","doi-asserted-by":"publisher","first-page":"573","DOI":"10.1177\/0271678X17733655","volume":"39","author":"J Hoffmann","year":"2019","unstructured":"Hoffmann J, Baca SM, Akerman S (2019) Neurovascular mechanisms of migraine and cluster headache. J Cereb Blood Flow Metab 39:573\u2013594. https:\/\/doi.org\/10.1177\/0271678X17733655","journal-title":"J Cereb Blood Flow Metab"},{"key":"1970_CR2","doi-asserted-by":"publisher","unstructured":"(2018) Headache Classification Committee of the International Headache Society (IHS) The International Classification of Headache Disorders, 3rd edition. Cephalalgia 38:1\u2013211. https:\/\/doi.org\/10.1177\/0333102417738202","DOI":"10.1177\/0333102417738202"},{"key":"1970_CR3","doi-asserted-by":"publisher","first-page":"304","DOI":"10.1016\/S1474-4422(20)30482-8","volume":"20","author":"KG Vetvik","year":"2021","unstructured":"Vetvik KG, MacGregor EA (2021) Menstrual migraine: a distinct disorder needing greater recognition. Lancet Neurol 20:304\u2013315. https:\/\/doi.org\/10.1016\/S1474-4422(20)30482-8","journal-title":"Lancet Neurol"},{"key":"1970_CR4","doi-asserted-by":"publisher","first-page":"42","DOI":"10.1007\/s11910-018-0845-3","volume":"18","author":"C Todd","year":"2018","unstructured":"Todd C, Lagman-Bartolome AM, Lay C (2018) Women and migraine: the role of hormones. Curr Neurol Neurosci Rep 18:42. https:\/\/doi.org\/10.1007\/s11910-018-0845-3","journal-title":"Curr Neurol Neurosci Rep"},{"key":"1970_CR5","doi-asserted-by":"publisher","first-page":"679","DOI":"10.1016\/S1474-4422(09)70090-0","volume":"8","author":"J Olesen","year":"2009","unstructured":"Olesen J, Burstein R, Ashina M, Tfelt-Hansen P (2009) Origin of pain in migraine: evidence for peripheral sensitisation. Lancet Neurol 8:679\u2013690. https:\/\/doi.org\/10.1016\/S1474-4422(09)70090-0","journal-title":"Lancet Neurol"},{"key":"1970_CR6","doi-asserted-by":"publisher","first-page":"365","DOI":"10.1146\/annurev-physiol-030212-183717","volume":"75","author":"D Pietrobon","year":"2013","unstructured":"Pietrobon D, Moskowitz MA (2013) Pathophysiology of Migraine. Annu Rev Physiol 75:365\u2013391. https:\/\/doi.org\/10.1146\/annurev-physiol-030212-183717","journal-title":"Annu Rev Physiol"},{"key":"1970_CR7","doi-asserted-by":"publisher","first-page":"e1825","DOI":"10.1212\/WNL.0000000000207114","volume":"100","author":"E Bianca Raffaelli","year":"2023","unstructured":"Bianca Raffaelli E, Storch LH, Overeem et al (2023) Sex hormones and calcitonin gene\u2013related peptide in Women with Migraine. Neurology 100:e1825. https:\/\/doi.org\/10.1212\/WNL.0000000000207114","journal-title":"Neurology"},{"key":"1970_CR8","doi-asserted-by":"publisher","first-page":"621","DOI":"10.1038\/s41582-021-00544-2","volume":"17","author":"DN Krause","year":"2021","unstructured":"Krause DN, Warfvinge K, Haanes KA, Edvinsson L (2021) Hormonal influences in migraine \u2014 interactions of oestrogen, oxytocin and CGRP. Nat Reviews Neurol 17:621\u2013633. https:\/\/doi.org\/10.1038\/s41582-021-00544-2","journal-title":"Nat Reviews Neurol"},{"key":"1970_CR9","doi-asserted-by":"publisher","first-page":"435","DOI":"10.1177\/0333102417739584","volume":"39","author":"A Labastida-Ram\u00edrez","year":"2019","unstructured":"Labastida-Ram\u00edrez A, Rubio-Beltr\u00e1n E, Villal\u00f3n CM, MaassenVanDenBrink A (2019) Gender aspects of CGRP in migraine. Cephalalgia 39:435\u2013444. https:\/\/doi.org\/10.1177\/0333102417739584","journal-title":"Cephalalgia"},{"key":"1970_CR10","doi-asserted-by":"publisher","first-page":"834","DOI":"10.1016\/S1474-4422(23)00152-7","volume":"22","author":"R Messina","year":"2023","unstructured":"Messina R, Rocca MA, Goadsby PJ, Filippi M (2023) Insights into migraine attacks from neuroimaging. Lancet Neurol 22:834\u2013846. https:\/\/doi.org\/10.1016\/S1474-4422(23)00152-7","journal-title":"Lancet Neurol"},{"key":"1970_CR11","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1016\/S1474-4422(14)70193-0","volume":"14","author":"TJ Schwedt","year":"2015","unstructured":"Schwedt TJ, Chiang C-C, Chong CD, Dodick DW (2015) Functional MRI of migraine. Lancet Neurol 14:81\u201391. https:\/\/doi.org\/10.1016\/S1474-4422(14)70193-0","journal-title":"Lancet Neurol"},{"key":"1970_CR12","doi-asserted-by":"publisher","first-page":"1496","DOI":"10.1016\/S0140-6736(20)32162-0","volume":"397","author":"M Ashina","year":"2021","unstructured":"Ashina M, Terwindt GM, Al-Karagholi MA-M et al (2021) Migraine: disease characterisation, biomarkers, and precision medicine. Lancet 397:1496\u20131504. https:\/\/doi.org\/10.1016\/S0140-6736(20)32162-0","journal-title":"Lancet"},{"key":"1970_CR13","doi-asserted-by":"publisher","unstructured":"Wang Z-w, Yin Z-h, Wang X, Zhang Y-t, Xu T, Du J-r, Wen Y, Liao H-q, Zhao Y, Liang F-r, Zhao L (2022) Brain structural and functional changes during menstrual migraine: relationships with pain. Front Mol Neurosci 15:967103. https:\/\/doi.org\/10.3389\/fnmol.2022.967103","DOI":"10.3389\/fnmol.2022.967103"},{"key":"1970_CR14","doi-asserted-by":"publisher","first-page":"741","DOI":"10.1007\/s00234-020-02623-5","volume":"63","author":"X Li","year":"2021","unstructured":"Li X, Khan A, Li Y et al (2021) Hyperconnection and hyperperfusion of overlapping brain regions in patients with menstrual-related migraine: a multimodal neuroimaging study. Neuroradiology 63:741\u2013749. https:\/\/doi.org\/10.1007\/s00234-020-02623-5","journal-title":"Neuroradiology"},{"key":"1970_CR15","doi-asserted-by":"publisher","first-page":"1450","DOI":"10.1007\/s11682-020-00344-0","volume":"15","author":"Y Zhang","year":"2021","unstructured":"Zhang Y, Xu T, Wang Z et al (2021) Differences in topological properties of functional brain networks between menstrually-related and non-menstrual migraine without aura. Brain Imaging Behav 15:1450\u20131459. https:\/\/doi.org\/10.1007\/s11682-020-00344-0","journal-title":"Brain Imaging Behav"},{"key":"1970_CR16","doi-asserted-by":"publisher","first-page":"16454","DOI":"10.1038\/s41598-020-73399-0","volume":"10","author":"T Xu","year":"2020","unstructured":"Xu T, Zhang Y, Wang C et al (2020) Brain structural and functional differences between pure menstrual migraine and menstrually-related migraine. Sci Rep 10:16454. https:\/\/doi.org\/10.1038\/s41598-020-73399-0","journal-title":"Sci Rep"},{"key":"1970_CR17","doi-asserted-by":"publisher","first-page":"534","DOI":"10.1002\/jmri.1076","volume":"13","author":"D Le Bihan","year":"2001","unstructured":"Le Bihan D, Mangin J-F, Poupon C et al (2001) Diffusion tensor imaging: concepts and applications. J Magn Reson Imaging 13:534\u2013546. https:\/\/doi.org\/10.1002\/jmri.1076","journal-title":"J Magn Reson Imaging"},{"key":"1970_CR18","doi-asserted-by":"publisher","first-page":"2375","DOI":"10.1007\/s11682-022-00690-1","volume":"16","author":"R Rahimi","year":"2022","unstructured":"Rahimi R, Dolatshahi M, Abbasi-Feijani F et al (2022) Microstructural white matter alterations associated with migraine headaches: a systematic review of diffusion tensor imaging studies. Brain Imaging Behav 16:2375\u20132401. https:\/\/doi.org\/10.1007\/s11682-022-00690-1","journal-title":"Brain Imaging Behav"},{"key":"1970_CR19","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s10194-019-1071-3","volume":"21","author":"\u00c1 Planchuelo-G\u00f3mez","year":"2020","unstructured":"Planchuelo-G\u00f3mez \u00c1, Garc\u00eda-Azor\u00edn D, Guerrero \u00c1L et al (2020) White matter changes in chronic and episodic migraine: a diffusion tensor imaging study. J Headache Pain 21:1. https:\/\/doi.org\/10.1186\/s10194-019-1071-3","journal-title":"J Headache Pain"},{"key":"1970_CR20","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1177\/0333102412466964","volume":"33","author":"D Yu","year":"2013","unstructured":"Yu D, Yuan K, Qin W et al (2013) Axonal loss of white matter in migraine without aura: a tract-based spatial statistics study. Cephalalgia 33:34\u201342. https:\/\/doi.org\/10.1177\/0333102412466964","journal-title":"Cephalalgia"},{"key":"1970_CR21","doi-asserted-by":"publisher","first-page":"501","DOI":"10.1136\/jnnp.74.4.501","volume":"74","author":"MA Rocca","year":"2003","unstructured":"Rocca MA, Colombo B, Inglese M et al (2003) A diffusion tensor magnetic resonance imaging study of brain tissue from patients with migraine. J Neurol Neurosurg Psychiatry 74:501. https:\/\/doi.org\/10.1136\/jnnp.74.4.501","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"1970_CR22","doi-asserted-by":"publisher","unstructured":"Fouto AR, Nunes RG, Guadilla I et al (2023) Episodic menstrual migraine patients exhibit white matter microstructural changes compared to hormonal controls. In: Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition. Toronto, Canada, p 2639. https:\/\/doi.org\/10.58530\/2023\/2639","DOI":"10.58530\/2023\/2639"},{"key":"1970_CR23","doi-asserted-by":"publisher","first-page":"483","DOI":"10.1038\/s41582-019-0216-y","volume":"15","author":"L Edvinsson","year":"2019","unstructured":"Edvinsson L, Haanes KA, Warfvinge K (2019) Does inflammation have a role in migraine? Nat Reviews Neurol 15:483\u2013490. https:\/\/doi.org\/10.1038\/s41582-019-0216-y","journal-title":"Nat Reviews Neurol"},{"key":"1970_CR24","doi-asserted-by":"publisher","first-page":"717","DOI":"10.1002\/mrm.22055","volume":"62","author":"O Pasternak","year":"2009","unstructured":"Pasternak O, Sochen N, Gur Y et al (2009) Free water elimination and mapping from diffusion MRI. Magn Reson Med 62:717\u2013730. https:\/\/doi.org\/10.1002\/mrm.22055","journal-title":"Magn Reson Med"},{"key":"1970_CR25","doi-asserted-by":"publisher","first-page":"17365","DOI":"10.1523\/JNEUROSCI.2904-12.2012","volume":"32","author":"C-F Ofer Pasternak","year":"2012","unstructured":"Ofer Pasternak C-F, Westin S, Bouix et al (2012) Excessive extracellular volume reveals a neurodegenerative pattern in Schizophrenia Onset. J Neurosci 32:17365. https:\/\/doi.org\/10.1523\/JNEUROSCI.2904-12.2012","journal-title":"J Neurosci"},{"key":"1970_CR26","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1186\/s13195-017-0292-4","volume":"9","author":"F Ji","year":"2017","unstructured":"Ji F, Pasternak O, Liu S et al (2017) Distinct white matter microstructural abnormalities and extracellular water increases relate to cognitive impairment in Alzheimer\u2019s disease with and without cerebrovascular disease. Alzheimer\u2019s Res Therapy 9:63. https:\/\/doi.org\/10.1186\/s13195-017-0292-4","journal-title":"Alzheimer\u2019s Res Therapy"},{"key":"1970_CR27","doi-asserted-by":"publisher","unstructured":"Fouto AR, Henriques RN, Golub M et al (2024) Impact of truncating diffusion MRI scans on diffusional kurtosis imaging. Magnetic Resonance Materials in Physics, Biology and Medicine. https:\/\/doi.org\/10.1007\/s10334-024-01153-y","DOI":"10.1007\/s10334-024-01153-y"},{"key":"1970_CR28","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1016\/j.mri.2023.06.010","volume":"102","author":"C Domingos","year":"2023","unstructured":"Domingos C, Fouto AR, Nunes RG et al (2023) Impact of susceptibility-induced distortion correction on perfusion imaging by pCASL with a segmented 3D GRASE readout. Magn Reson Imaging 102:141\u2013150. https:\/\/doi.org\/10.1016\/j.mri.2023.06.010","journal-title":"Magn Reson Imaging"},{"key":"1970_CR29","doi-asserted-by":"publisher","first-page":"1201","DOI":"10.1007\/s10072-023-07120-0","volume":"45","author":"A Ruiz-Tagle","year":"2024","unstructured":"Ruiz-Tagle A, Figueiredo P, Pinto J et al (2024) Working memory during spontaneous migraine attacks: an fMRI study. Neurol Sci 45:1201\u20131208. https:\/\/doi.org\/10.1007\/s10072-023-07120-0","journal-title":"Neurol Sci"},{"key":"1970_CR30","doi-asserted-by":"publisher","first-page":"532","DOI":"10.1016\/j.neuroimage.2018.07.066","volume":"183","author":"B Ades-Aron","year":"2018","unstructured":"Ades-Aron B, Veraart J, Kochunov P et al (2018) Evaluation of the accuracy and precision of the diffusion parameter EStImation with Gibbs and NoisE removal pipeline. NeuroImage 183:532\u2013543. https:\/\/doi.org\/10.1016\/j.neuroimage.2018.07.066","journal-title":"NeuroImage"},{"key":"1970_CR31","doi-asserted-by":"publisher","first-page":"1028","DOI":"10.1002\/mrm.28997","volume":"87","author":"A Trist\u00e1n-Vega","year":"2022","unstructured":"Trist\u00e1n-Vega A, Par\u00eds G, de Luis-Garc\u00eda R, Aja-Fern\u00e1ndez S (2022) Accurate free-water estimation in white matter from fast diffusion MRI acquisitions using the spherical means technique. Magn Reson Med 87:1028\u20131035. https:\/\/doi.org\/10.1002\/mrm.28997","journal-title":"Magn Reson Med"},{"key":"1970_CR32","unstructured":"Pierpaoli C, Jones DK (2004) Removing CSF Contamination in Brain DT-MRIs by Using a Two-Compartment Tensor Model. In: Proceedings International Society for Magnetic Resonance in Medicine. Melbourne, Australia, p 1215"},{"key":"1970_CR33","doi-asserted-by":"publisher","first-page":"1088","DOI":"10.1002\/mrm.20426","volume":"53","author":"L-C Chang","year":"2005","unstructured":"Chang L-C, Jones DK, Pierpaoli C (2005) RESTORE: robust estimation of tensors by outlier rejection. Magn Reson Med 53:1088\u20131095. https:\/\/doi.org\/10.1002\/mrm.20426","journal-title":"Magn Reson Med"},{"key":"1970_CR34","doi-asserted-by":"publisher","first-page":"1487","DOI":"10.1016\/j.neuroimage.2006.02.024","volume":"31","author":"SM Smith","year":"2006","unstructured":"Smith SM, Jenkinson M, Johansen-Berg H et al (2006) Tract-based spatial statistics: Voxelwise analysis of multi-subject diffusion data. NeuroImage 31:1487\u20131505. https:\/\/doi.org\/10.1016\/j.neuroimage.2006.02.024","journal-title":"NeuroImage"},{"key":"1970_CR35","doi-asserted-by":"publisher","first-page":"447","DOI":"10.1016\/j.neuroimage.2008.07.009","volume":"43","author":"K Oishi","year":"2008","unstructured":"Oishi K, Zilles K, Amunts K et al (2008) Human brain white matter atlas: identification and assignment of common anatomical structures in superficial white matter. NeuroImage 43:447\u2013457. https:\/\/doi.org\/10.1016\/j.neuroimage.2008.07.009","journal-title":"NeuroImage"},{"key":"1970_CR36","doi-asserted-by":"publisher","first-page":"381","DOI":"10.1016\/j.neuroimage.2014.01.060","volume":"92","author":"AM Winkler","year":"2014","unstructured":"Winkler AM, Ridgway GR, Webster MA et al (2014) Permutation inference for the general linear model. NeuroImage 92:381\u2013397. https:\/\/doi.org\/10.1016\/j.neuroimage.2014.01.060","journal-title":"NeuroImage"},{"key":"1970_CR37","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1007\/s00415-022-11398-z","volume":"270","author":"\u00c1 Planchuelo-G\u00f3mez","year":"2023","unstructured":"Planchuelo-G\u00f3mez \u00c1, Garc\u00eda-Azor\u00edn D, Guerrero \u00c1L et al (2023) Structural brain changes in patients with persistent headache after COVID-19 resolution. J Neurol 270:13\u201331. https:\/\/doi.org\/10.1007\/s00415-022-11398-z","journal-title":"J Neurol"},{"key":"1970_CR38","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1016\/j.clineuro.2018.09.022","volume":"174","author":"Y Shibata","year":"2018","unstructured":"Shibata Y, Ishiyama S, Matsushita A (2018) White matter diffusion abnormalities in migraine and medication overuse headache: a 1.5-T tract-based spatial statistics study. Clin Neurol Neurosurg 174:167\u2013173. https:\/\/doi.org\/10.1016\/j.clineuro.2018.09.022","journal-title":"Clin Neurol Neurosurg"},{"key":"1970_CR39","doi-asserted-by":"publisher","first-page":"1103","DOI":"10.1002\/nbm.2924","volume":"26","author":"D Yu","year":"2013","unstructured":"Yu D, Yuan K, Zhao L et al (2013) White matter integrity affected by depressive symptoms in migraine without aura: a tract-based spatial statistics study. NMR Biomed 26:1103\u20131112. https:\/\/doi.org\/10.1002\/nbm.2924","journal-title":"NMR Biomed"},{"key":"1970_CR40","doi-asserted-by":"publisher","first-page":"R57","DOI":"10.1088\/0031-9155\/52\/7\/R02","volume":"52","author":"D Le Bihan","year":"2007","unstructured":"Le Bihan D (2007) The \u2018wet mind\u2019: water and functional neuroimaging. Phys Med Biol 52:R57. https:\/\/doi.org\/10.1088\/0031-9155\/52\/7\/R02","journal-title":"Phys Med Biol"},{"key":"1970_CR41","doi-asserted-by":"publisher","first-page":"14472","DOI":"10.1073\/pnas.1004841107","volume":"107","author":"MD Budde","year":"2010","unstructured":"Budde MD, Frank JA (2010) Neurite beading is sufficient to decrease the apparent diffusion coefficient after ischemic stroke. Proc Natl Acad Sci 107:14472\u201314477. https:\/\/doi.org\/10.1073\/pnas.1004841107","journal-title":"Proc Natl Acad Sci"},{"key":"1970_CR42","doi-asserted-by":"publisher","first-page":"758","DOI":"10.1016\/j.it.2020.07.004","volume":"41","author":"MV Sofroniew","year":"2020","unstructured":"Sofroniew MV (2020) Astrocyte reactivity: subtypes, States, and functions in CNS innate immunity. Trends Immunol 41:758\u2013770. https:\/\/doi.org\/10.1016\/j.it.2020.07.004","journal-title":"Trends Immunol"},{"key":"1970_CR43","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1007\/s00401-021-02389-x","volume":"143","author":"S Amor","year":"2022","unstructured":"Amor S, McNamara NB, Gerrits E et al (2022) White matter microglia heterogeneity in the CNS. Acta Neuropathol 143:125\u2013141. https:\/\/doi.org\/10.1007\/s00401-021-02389-x","journal-title":"Acta Neuropathol"},{"key":"1970_CR44","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1152\/physrev.00042.2016","volume":"98","author":"A Verkhratsky","year":"2018","unstructured":"Verkhratsky A, Nedergaard M (2018) Physiology of Astroglia. Physiol Rev 98:239\u2013389. https:\/\/doi.org\/10.1152\/physrev.00042.2016","journal-title":"Physiol Rev"},{"key":"1970_CR45","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1186\/s10194-022-01430-y","volume":"23","author":"RH Christensen","year":"2022","unstructured":"Christensen RH, Gollion C, Amin FM et al (2022) Imaging the inflammatory phenotype in migraine. J Headache Pain 23:60. https:\/\/doi.org\/10.1186\/s10194-022-01430-y","journal-title":"J Headache Pain"},{"key":"1970_CR46","doi-asserted-by":"publisher","first-page":"1565","DOI":"10.1177\/03331024221118924","volume":"42","author":"J Thuraiaiyah","year":"2022","unstructured":"Thuraiaiyah J, Erritz\u00f8e-Jervild M, Al-Khazali HM et al (2022) The role of cytokines in migraine: a systematic review. Cephalalgia 42:1565\u20131588. https:\/\/doi.org\/10.1177\/03331024221118924","journal-title":"Cephalalgia"},{"key":"1970_CR47","doi-asserted-by":"publisher","first-page":"926","DOI":"10.1111\/j.1526-4610.2005.05135.x","volume":"45","author":"F Perini","year":"2005","unstructured":"Perini F, D\u2019Andrea G, Galloni E, et al et al (2005) Plasma cytokine levels in migraineurs and controls. Headache: J Head Face Pain 45:926\u2013931. https:\/\/doi.org\/10.1111\/j.1526-4610.2005.05135.x","journal-title":"Headache: J Head Face Pain"},{"key":"1970_CR48","doi-asserted-by":"publisher","first-page":"200","DOI":"10.1111\/j.1526-4610.2006.00337.x","volume":"46","author":"P Sarchielli","year":"2006","unstructured":"Sarchielli P, Alberti A, Baldi A et al (2006) Proinflammatory cytokines, adhesion molecules, and lymphocyte integrin expression in the Internal Jugular blood of Migraine patients without Aura Assessed Ictally. Headache: J Head Face Pain 46:200\u2013207. https:\/\/doi.org\/10.1111\/j.1526-4610.2006.00337.x","journal-title":"Headache: J Head Face Pain"},{"key":"1970_CR49","first-page":"1111","volume":"15","author":"E Uzar","year":"2011","unstructured":"Uzar E, Evliyao\u011flu O, Yucel Y et al (2011) Serum cytokine and pro-brain natriuretic peptide (BNP) levels in patients with migraine. Eur Rev Med Pharmacol Sci 15:1111\u20131116","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"1970_CR50","doi-asserted-by":"publisher","first-page":"138","DOI":"10.1016\/j.jneuroim.2017.09.008","volume":"313","author":"AB Oliveira","year":"2017","unstructured":"Oliveira AB, Bachi ALL, Ribeiro RT et al (2017) Unbalanced plasma TNF-\u03b1 and IL-12\/IL-10 profile in women with migraine is associated with psychological and physiological outcomes. J Neuroimmunol 313:138\u2013144. https:\/\/doi.org\/10.1016\/j.jneuroim.2017.09.008","journal-title":"J Neuroimmunol"},{"key":"1970_CR51","doi-asserted-by":"publisher","first-page":"184","DOI":"10.1016\/j.jneuroim.2005.10.005","volume":"171","author":"I Fidan","year":"2006","unstructured":"Fidan I, Y\u00fcksel S, \u00ddmir T et al (2006) The importance of cytokines, chemokines and nitric oxide in pathophysiology of migraine. J Neuroimmunol 171:184\u2013188. https:\/\/doi.org\/10.1016\/j.jneuroim.2005.10.005","journal-title":"J Neuroimmunol"},{"key":"1970_CR52","doi-asserted-by":"publisher","first-page":"643","DOI":"10.1016\/j.brs.2019.01.008","volume":"12","author":"SR Chaudhry","year":"2019","unstructured":"Chaudhry SR, Lendvai IS, Muhammad S et al (2019) Inter-ictal assay of peripheral circulating inflammatory mediators in migraine patients under adjunctive cervical non-invasive vagus nerve stimulation (nVNS): a proof-of-concept study. Brain Stimul 12:643\u2013651. https:\/\/doi.org\/10.1016\/j.brs.2019.01.008","journal-title":"Brain Stimul"},{"key":"1970_CR53","doi-asserted-by":"publisher","first-page":"323","DOI":"10.1016\/j.neuroimage.2014.09.053","volume":"103","author":"AR Hoy","year":"2014","unstructured":"Hoy AR, Koay CG, Kecskemeti SR, Alexander AL (2014) Optimization of a free water elimination two-compartment model for diffusion tensor imaging. NeuroImage 103:323\u2013333. https:\/\/doi.org\/10.1016\/j.neuroimage.2014.09.053","journal-title":"NeuroImage"},{"key":"1970_CR54","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1002\/hbm.23350","volume":"38","author":"A Albi","year":"2017","unstructured":"Albi A, Pasternak O, Minati L et al (2017) Free water elimination improves test\u2013retest reproducibility of diffusion tensor imaging indices in the brain: a longitudinal multisite study of healthy elderly subjects. Hum Brain Mapp 38:12\u201326. https:\/\/doi.org\/10.1002\/hbm.23350","journal-title":"Hum Brain Mapp"},{"key":"1970_CR55","doi-asserted-by":"publisher","first-page":"e0242696","DOI":"10.1371\/journal.pone.0242696","volume":"15","author":"M Edde","year":"2020","unstructured":"Edde M, Theaud G, Rheault F et al (2020) Free water: a marker of age-related modifications of the cingulum white matter and its association with cognitive decline. PLoS ONE 15:e0242696. https:\/\/doi.org\/10.1371\/journal.pone.0242696","journal-title":"PLoS ONE"},{"key":"1970_CR56","doi-asserted-by":"publisher","first-page":"1572","DOI":"10.1002\/jmri.24925","volume":"42","author":"AR Hoy","year":"2015","unstructured":"Hoy AR, Kecskemeti SR, Alexander AL (2015) Free water elimination diffusion tractography: a comparison with conventional and fluid-attenuated inversion recovery, diffusion tensor imaging acquisitions. J Magn Reson Imaging 42:1572\u20131581. https:\/\/doi.org\/10.1002\/jmri.24925","journal-title":"J Magn Reson Imaging"},{"key":"1970_CR57","doi-asserted-by":"publisher","first-page":"557","DOI":"10.1016\/j.bbi.2023.11.006","volume":"115","author":"D Wu","year":"2024","unstructured":"Wu D, Wu Q, Li F et al (2024) Free water alterations in different inflammatory subgroups in schizophrenia. Brain Behav Immun 115:557\u2013564. https:\/\/doi.org\/10.1016\/j.bbi.2023.11.006","journal-title":"Brain Behav Immun"},{"key":"1970_CR58","doi-asserted-by":"publisher","first-page":"1675","DOI":"10.1177\/0333102418791595","volume":"39","author":"S Younis","year":"2019","unstructured":"Younis S, Hougaard A, Noseda R, Ashina M (2019) Current understanding of thalamic structure and function in migraine. Cephalalgia 39:1675\u20131682. https:\/\/doi.org\/10.1177\/0333102418791595","journal-title":"Cephalalgia"},{"key":"1970_CR59","doi-asserted-by":"publisher","first-page":"287","DOI":"10.1111\/ene.12296","volume":"21","author":"G Coppola","year":"2014","unstructured":"Coppola G, Tinelli E, Lepre C et al (2014) Dynamic changes in thalamic microstructure of migraine without aura patients: a diffusion tensor magnetic resonance imaging study. Eur J Neurol 21:287\u2013e13. https:\/\/doi.org\/10.1111\/ene.12296","journal-title":"Eur J Neurol"},{"key":"1970_CR60","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1038\/nrneurol.2009.28","volume":"5","author":"A May","year":"2009","unstructured":"May A (2009) New insights into headache: an update on functional and structural imaging findings. Nat Reviews Neurol 5:199\u2013209. https:\/\/doi.org\/10.1038\/nrneurol.2009.28","journal-title":"Nat Reviews Neurol"},{"key":"1970_CR61","doi-asserted-by":"publisher","first-page":"1315","DOI":"10.1016\/S0140-6736(18)30478-1","volume":"391","author":"DW Dodick","year":"2018","unstructured":"Dodick DW (2018) Migraine. Lancet 391:1315\u20131330. https:\/\/doi.org\/10.1016\/S0140-6736(18)30478-1","journal-title":"Lancet"},{"key":"1970_CR62","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1161\/01.STR.32.1.107","volume":"32","author":"F Shelton","year":"2001","unstructured":"Shelton F, de NAP, Reding MJ (2001) Effect of Lesion Location on Upper Limb Motor Recovery after Stroke. Stroke 32:107\u2013112. https:\/\/doi.org\/10.1161\/01.STR.32.1.107","journal-title":"Stroke"},{"key":"1970_CR63","doi-asserted-by":"publisher","first-page":"1438","DOI":"10.1212\/01.WNL.0000158656.09335.E7","volume":"64","author":"S Jong","year":"2005","unstructured":"Jong S, Kim A, Pope (2005) Somatotopically located motor fibers in corona radiata: evidence from subcortical small infarcts. Neurology 64:1438. https:\/\/doi.org\/10.1212\/01.WNL.0000158656.09335.E7","journal-title":"Neurology"},{"key":"1970_CR64","doi-asserted-by":"publisher","first-page":"1532","DOI":"10.1016\/j.neubiorev.2012.04.002","volume":"36","author":"M Vandermosten","year":"2012","unstructured":"Vandermosten M, Boets B, Wouters J, Ghesqui\u00e8re P (2012) A qualitative and quantitative review of diffusion tensor imaging studies in reading and dyslexia. Neurosci Biobehavioral Reviews 36:1532\u20131552. https:\/\/doi.org\/10.1016\/j.neubiorev.2012.04.002","journal-title":"Neurosci Biobehavioral Reviews"},{"key":"1970_CR65","doi-asserted-by":"publisher","first-page":"358","DOI":"10.1016\/j.neuroimage.2010.04.001","volume":"52","author":"L van Eimeren","year":"2010","unstructured":"van Eimeren L, Grabner RH, Koschutnig K et al (2010) Structure-function relationships underlying calculation: a combined diffusion tensor imaging and fMRI study. NeuroImage 52:358\u2013363. https:\/\/doi.org\/10.1016\/j.neuroimage.2010.04.001","journal-title":"NeuroImage"},{"key":"1970_CR66","doi-asserted-by":"publisher","first-page":"1040","DOI":"10.1177\/0333102414527649","volume":"34","author":"K-H Chou","year":"2014","unstructured":"Chou K-H, Yang F-C, Fuh J-L et al (2014) Altered white matter microstructural connectivity in cluster headaches: a longitudinal diffusion tensor imaging study. Cephalalgia 34:1040\u20131052. https:\/\/doi.org\/10.1177\/0333102414527649","journal-title":"Cephalalgia"},{"key":"1970_CR67","doi-asserted-by":"crossref","unstructured":"Dong D, Hosomi K, Mori N et al. White matter microstructural alterations in patients with neuropathic pain after spinal cord injury: a diffusion tensor imaging study. Front Neurol, 2023:14","DOI":"10.3389\/fneur.2023.1241658"},{"key":"1970_CR68","doi-asserted-by":"publisher","first-page":"e0195672","DOI":"10.1371\/journal.pone.0195672","volume":"13","author":"MP Hyett","year":"2018","unstructured":"Hyett MP, Perry A, Breakspear M et al (2018) White matter alterations in the internal capsule and psychomotor impairment in melancholic depression. PLoS ONE 13:e0195672. https:\/\/doi.org\/10.1371\/journal.pone.0195672","journal-title":"PLoS ONE"},{"key":"1970_CR69","doi-asserted-by":"publisher","first-page":"80","DOI":"10.1186\/s10194-023-01620-2","volume":"24","author":"Y Mei","year":"2023","unstructured":"Mei Y, Wang W, Qiu D et al (2023) Micro-structural white matter abnormalities in new daily persistent headache: a DTI study using TBSS analysis. J Headache Pain 24:80. https:\/\/doi.org\/10.1186\/s10194-023-01620-2","journal-title":"J Headache Pain"},{"key":"1970_CR70","doi-asserted-by":"crossref","unstructured":"Michels L, St\u00e4mpfli P, Aldusary N et al. Widespread white matter alterations in patients with visual Snow Syndrome. Front Neurol. 2021:12","DOI":"10.3389\/fneur.2021.723805"},{"key":"1970_CR71","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1016\/j.yebeh.2017.09.002","volume":"77","author":"Q Huang","year":"2017","unstructured":"Huang Q, Lv X, He Y et al (2017) Structural differences in interictal migraine attack after epilepsy: a diffusion tensor imaging analysis. Epilepsy Behav 77:8\u201312. https:\/\/doi.org\/10.1016\/j.yebeh.2017.09.002","journal-title":"Epilepsy Behav"},{"key":"1970_CR72","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1186\/s10194-019-1045-5","volume":"20","author":"Z Qin","year":"2019","unstructured":"Qin Z, He X-W, Zhang J et al (2019) Structural changes of cerebellum and brainstem in migraine without aura. J Headache Pain 20:93. https:\/\/doi.org\/10.1186\/s10194-019-1045-5","journal-title":"J Headache Pain"},{"key":"1970_CR73","doi-asserted-by":"publisher","first-page":"2055","DOI":"10.1093\/cercor\/bhp280","volume":"20","author":"LT Westlye","year":"2010","unstructured":"Westlye LT, Walhovd KB, Dale AM et al (2010) Life-span changes of the human brain White Matter: Diffusion Tensor Imaging (DTI) and Volumetry. Cereb Cortex 20:2055\u20132068. https:\/\/doi.org\/10.1093\/cercor\/bhp280","journal-title":"Cereb Cortex"},{"key":"1970_CR74","doi-asserted-by":"publisher","first-page":"117441","DOI":"10.1016\/j.neuroimage.2020.117441","volume":"224","author":"D Beck","year":"2021","unstructured":"Beck D, de Lange A-MG, Maximov II et al (2021) White matter microstructure across the adult lifespan: a mixed longitudinal and cross-sectional study using advanced diffusion models and brain-age prediction. NeuroImage 224:117441. https:\/\/doi.org\/10.1016\/j.neuroimage.2020.117441","journal-title":"NeuroImage"},{"key":"1970_CR75","doi-asserted-by":"publisher","first-page":"120324","DOI":"10.1016\/j.neuroimage.2023.120324","volume":"279","author":"T Pieciak","year":"2023","unstructured":"Pieciak T, Par\u00eds G, Beck D et al (2023) Spherical means-based free-water volume fraction from diffusion MRI increases non-linearly with age in the white matter of the healthy human brain. NeuroImage 279:120324. https:\/\/doi.org\/10.1016\/j.neuroimage.2023.120324","journal-title":"NeuroImage"},{"key":"1970_CR76","doi-asserted-by":"publisher","unstructured":"Hartikainen KM (2021) Emotion-attention Interaction in the right hemisphere. https:\/\/doi.org\/10.3390\/brainsci11081006. Brain Sciences 11:","DOI":"10.3390\/brainsci11081006"},{"key":"1970_CR77","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1016\/j.neures.2010.06.013","volume":"68","author":"D Hecht","year":"2010","unstructured":"Hecht D (2010) Depression and the hyperactive right-hemisphere. Neurosci Res 68:77\u201387. https:\/\/doi.org\/10.1016\/j.neures.2010.06.013","journal-title":"Neurosci Res"},{"key":"1970_CR78","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1186\/s10194-016-0593-1","volume":"17","author":"M Gomez-Beldarrain","year":"2016","unstructured":"Gomez-Beldarrain M, Oroz I, Zapirain BG et al (2016) Right fronto-insular white matter tracts link cognitive reserve and pain in migraine patients. J Headache Pain 17:4. https:\/\/doi.org\/10.1186\/s10194-016-0593-1","journal-title":"J Headache Pain"},{"key":"1970_CR79","doi-asserted-by":"publisher","first-page":"6990","DOI":"10.1038\/s41598-021-86505-7","volume":"11","author":"M Bergamino","year":"2021","unstructured":"Bergamino M, Walsh RR, Stokes AM (2021) Free-water diffusion tensor imaging improves the accuracy and sensitivity of white matter analysis in Alzheimer\u2019s disease. Sci Rep 11:6990. https:\/\/doi.org\/10.1038\/s41598-021-86505-7","journal-title":"Sci Rep"}],"container-title":["The Journal of Headache and Pain"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s10194-025-01970-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s10194-025-01970-z\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s10194-025-01970-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,12]],"date-time":"2025-02-12T19:45:39Z","timestamp":1739389539000},"score":1,"resource":{"primary":{"URL":"https:\/\/thejournalofheadacheandpain.biomedcentral.com\/articles\/10.1186\/s10194-025-01970-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2,12]]},"references-count":79,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["1970"],"URL":"https:\/\/doi.org\/10.1186\/s10194-025-01970-z","relation":{},"ISSN":["1129-2377"],"issn-type":[{"value":"1129-2377","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,2,12]]},"assertion":[{"value":"26 August 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 January 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 February 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"All experimental procedures were approved by the Health Ethics Commission of Hospital da Luz (CES\/46\/2018\/ME) and conducted in compliance with the Declaration of Helsinki, Good Clinical Practice and all applicable regulations and laws. All subjects gave written informed consent.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"The authors declare no confict of interests. The authors declare that the research was conducted in the absence of any commercial or fnancial relationships that could be construed as a potential confict of interest.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"31"}}