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We aimed to identify implementation barriers and facilitators of four primary care interventions: physical activity assessment, counselling, prescription, and referral.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>A systematic review of qualitative, quantitative and mixed-methods studies published since 2016 was conducted. The \u201cTailored Implementation for Chronic Diseases\u201d (TICD) framework was adapted to extract and synthesize barriers and facilitators.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Sixty-two studies met the inclusion criteria. Barriers (<jats:italic>n<\/jats:italic>\u2009=\u200956) and facilitators (<jats:italic>n<\/jats:italic>\u2009=\u200955) were identified across seven domains, related to characteristics of the intervention, individual factors of the implementers and receivers, organizational factors, and political and social determinants. The five most frequently reported determinants were: professionals\u2019 knowledge and skills; intervention feasibility\/compatibility with primary health care routine; interventions\u2019 cost and financial incentives; tools and materials; and professionals\u2019 cognitions and attitudes. \u201cSocial, political and legal factors\u201d domain was the least reported. Physical activity counselling, prescription, and referral were influenced by determinants belonging to all the seven domains.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>The implementation of physical activity interventions in primary care is influenced by a broader range of determinants. Barriers and facilitators related with health professionals, intervention characteristics, and available resources were the most frequently reported. A deep understanding of the local context, with particularly emphasis on these determinants, should be considered when preparing an intervention implementation, in order to contribute for designing tailored implementation strategies and optimize the interventions\u2019 effectiveness.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12913-023-09881-y","type":"journal-article","created":{"date-parts":[[2023,10,11]],"date-time":"2023-10-11T12:02:50Z","timestamp":1697025770000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Implementation determinants of physical activity interventions in primary health care settings using the TICD framework: a systematic review"],"prefix":"10.1186","volume":"23","author":[{"given":"Catarina Santos","family":"Silva","sequence":"first","affiliation":[]},{"given":"Cristina","family":"Godinho","sequence":"additional","affiliation":[]},{"given":"Jorge","family":"Encantado","sequence":"additional","affiliation":[]},{"given":"Bruno","family":"Rodrigues","sequence":"additional","affiliation":[]},{"given":"Eliana V.","family":"Carra\u00e7a","sequence":"additional","affiliation":[]},{"given":"Pedro J.","family":"Teixeira","sequence":"additional","affiliation":[]},{"given":"Marlene Nunes","family":"Silva","sequence":"additional","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2023,10,11]]},"reference":[{"issue":"9838","key":"9881_CR1","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1016\/S0140-6736(12)61031-9","volume":"380","author":"IM Lee","year":"2012","unstructured":"Lee IM, Shiroma EJ, Lobelo F, Puska P, Blair SN, Katzmarzyk PT, et al. 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