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The procedure identifies syntenic blocks of DNA separated in the human karyotype that are associated in the closely related alpaca and dromedary (<jats:italic>Camelus dromedarius<\/jats:italic>) karyotypes. This example provides proof of principal for the validity of the method for comparative chromosome mapping.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>It is suggested that the approach presented here may have application in the construction of comparative chromosome maps between distantly related taxa, such as monotremes and mammals.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s13039-022-00622-0","type":"journal-article","created":{"date-parts":[[2022,10,7]],"date-time":"2022-10-07T16:04:14Z","timestamp":1665158654000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Observations on chromosome-specific sequencing for the construction of cross-species chromosome homology maps and its resolution of human:alpaca homology"],"prefix":"10.1186","volume":"15","author":[{"given":"Malcolm A.","family":"Ferguson-Smith","sequence":"first","affiliation":[]},{"given":"Jorge C.","family":"Pereira","sequence":"additional","affiliation":[]},{"given":"Ana","family":"Borges","sequence":"additional","affiliation":[]},{"given":"Fumio","family":"Kasai","sequence":"additional","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2022,10,7]]},"reference":[{"key":"622_CR1","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1111\/j.1399-0004.1984.tb00780.x","volume":"26","author":"VJ Buckle","year":"1984","unstructured":"Buckle VJ, Edwards JH, Evans EP, Jonasson JA, Lyon MF, Peters J, Searle AG, Wedd NS. 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