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Intensive Care"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Severe infections and multidrug-resistant pathogens are common in critically ill patients. Antimicrobial stewardship (AMS) and therapeutic drug monitoring (TDM) are contemporary tools to optimize the use of antimicrobials. The A-TEAMICU survey was initiated to gain contemporary insights into dissemination and structure of AMS programs and TDM practices in intensive care units.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This study involved online survey of members of ESICM and six national professional intensive care societies.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Data of 812 respondents from mostly European high- and middle-income countries were available for analysis. 63% had AMS rounds available in their ICU, where 78% performed rounds weekly or more often. While 82% had local guidelines for treatment of infections, only 70% had cumulative antimicrobial susceptibility reports and 56% monitored the quantity of antimicrobials administered. A restriction of antimicrobials was reported by 62%. TDM of antimicrobial agents was used in 61% of ICUs, mostly glycopeptides (89%), aminoglycosides (77%), carbapenems (32%), penicillins (30%), azole antifungals (27%), cephalosporins (17%), and linezolid (16%). 76% of respondents used prolonged\/continuous infusion of antimicrobials. The availability of an AMS had a significant association with the use of TDM.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Many respondents of the survey have AMS in their ICUs. TDM of antimicrobials and optimized administration of antibiotics are broadly used among respondents. The availability of antimicrobial susceptibility reports and a surveillance of antimicrobial use should be actively sought by intensivists where unavailable. Results of this survey may inform further research and educational activities.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s13613-021-00917-2","type":"journal-article","created":{"date-parts":[[2021,8,26]],"date-time":"2021-08-26T06:03:55Z","timestamp":1629957835000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":33,"title":["Antimicrobial stewardship, therapeutic drug monitoring and infection management in the ICU: results from the international A- TEAMICU survey"],"prefix":"10.1016","volume":"11","author":[{"given":"Christian","family":"Lanckohr","sequence":"first","affiliation":[]},{"given":"Christian","family":"Boeing","sequence":"additional","affiliation":[]},{"given":"Jan J.","family":"De Waele","sequence":"additional","affiliation":[]},{"given":"Dylan W.","family":"de Lange","sequence":"additional","affiliation":[]},{"given":"Jeroen","family":"Schouten","sequence":"additional","affiliation":[]},{"given":"Menno","family":"Prins","sequence":"additional","affiliation":[]},{"given":"Maarten","family":"Nijsten","sequence":"additional","affiliation":[]},{"given":"Pedro","family":"Povoa","sequence":"additional","affiliation":[]},{"given":"Andrew Conway","family":"Morris","sequence":"additional","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7495-7302","authenticated-orcid":false,"given":"Hendrik","family":"Bracht","sequence":"additional","affiliation":[]}],"member":"78","published-online":{"date-parts":[[2021,8,26]]},"reference":[{"issue":"1","key":"917_CR1","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1016\/S1473-3099(18)30605-4","volume":"19","author":"A Cassini","year":"2019","unstructured":"Cassini A, Hogberg LD, Plachouras D, Quattrocchi A, Hoxha A, Simonsen GS, et al. 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