{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T03:52:14Z","timestamp":1774583534769,"version":"3.50.1"},"reference-count":33,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2021,7,5]],"date-time":"2021-07-05T00:00:00Z","timestamp":1625443200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2021,7,5]],"date-time":"2021-07-05T00:00:00Z","timestamp":1625443200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eye and Vis"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>To identify biometric and implantable collamer lens (ICL)-related risk factors associated with sub-optimal postoperative vault in eyes implanted with phakic ICL.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>This study reports a retrospective case series of the first operated eye in 360 patients implanted with myopic spherical or toric ICL. Preoperatively, white-to-white (WTW), central keratometry (Kc) and central corneal thickness (CCT) were measured using the Pentacam. Anterior-segment optical coherence tomography (AS-OCT, Visante) was applied preoperatively for measuring the horizontal anterior-chamber angle-to-angle distance (ATA), internal anterior chamber depth (ACD), crystalline lens rise (CLR), anterior-chamber angle (ACA) and postoperatively the vault. Eyes were divided into three vault groups: low (LVG: \u2264\u00a0250\u2009\u03bcm), optimal (OVG: &gt;\u2009250 and\u2009&lt;\u20091000\u2009\u03bcm) and high (HVG: \u2265\u00a01000\u2009\u03bcm). Multinomial logistic regression (MLR) was used to find the sub-optimal vault predictors.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>MLR showed that CLR, ICL size minus the ATA (ICL size-ATA), age, ICL spherical equivalent (ICLSE) and ICL size as contributing factors for sub-optimal vaults (pseudo-<jats:italic>R<\/jats:italic><jats:sup><jats:italic>2<\/jats:italic><\/jats:sup>\u2009=\u20090.40). Increased CLR (OR: 1.01, CI: 1.00\u20131.01) and less myopic ICLSE (OR: 1.22, CI: 1.07\u20131.40) were risk factors for low vaults. Larger ICL size-ATA (OR: 41.29, CI: 10.57\u2013161.22) and the 13.7\u2009mm ICL (OR: 7.08, CI: 3.16\u201315.89) were risk factors for high vaults, whereas less myopic ICLSE (OR: 0.85, CI: 0.76\u20130.95) and older age (OR: 0.92, CI: 0.88\u20130.98) were protective factors.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>High CLR and low ICLSE were the major risk factors in eyes presenting low vaults. In the opposite direction, ICL size-ATA was the major contributor for high vaults. This relationship was more critical in higher myopic ICLSE, younger eyes and when 13.7\u2009mm ICL were used. The findings show that factors influencing the vault have differentiated weight of influence depending on the type of vault (low, optimal or high).<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s40662-021-00250-6","type":"journal-article","created":{"date-parts":[[2021,7,5]],"date-time":"2021-07-05T08:10:58Z","timestamp":1625472658000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":50,"title":["Biometric and ICL-related risk factors associated to sub-optimal vaults in eyes implanted with implantable collamer lenses"],"prefix":"10.1186","volume":"8","author":[{"given":"Santiago","family":"Cerpa Manito","sequence":"first","affiliation":[]},{"given":"Angel","family":"S\u00e1nchez Tranc\u00f3n","sequence":"additional","affiliation":[]},{"given":"Oscar","family":"Torrado Sierra","sequence":"additional","affiliation":[]},{"given":"Ant\u00f3nio Manuel","family":"Baptista","sequence":"additional","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0471-0213","authenticated-orcid":false,"given":"Pedro Miguel","family":"Serra","sequence":"additional","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2021,7,5]]},"reference":[{"key":"250_CR1","doi-asserted-by":"crossref","unstructured":"Sanders DR, Doney K, Poco M, ICL in Treatment of Myopia Study Group. 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