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The human skin is the first line of photoprotection against harmful exogenous factors, such as UV radiations. The topical application of sunscreens, containing UV-B filters, is widely used to protect against UV-induced damage. Octylmethoxycinnamate is the world\u2019s most widely used UV-B filter in sunscreens. However, recent studies have demonstrated that this substance is an endocrine disruptor compound and with potential to damage DNA. Thus, the safety of this organic filter is a current concern for human health, and it was urgent to develop new photoprotective strategies. In this sense, due to the potential to neutralize the UV-induced free radicals, the use of antioxidants as UV filter stabilizers presented as a novel promising strategy.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Research<\/jats:title>\n                <jats:p>The purpose of this review was to assess the use of antioxidants as stabilizers for UV-B filter octylmethoxycinnamate. For this, we discuss the chemical and physical characteristics of UV-B filter octylmethoxycinnamate, emphasizing the stability, photostability, and reactivity of this UV filter. The use of antioxidants in sunscreens will also be addressed, from a perspective of the main characteristics that allowed their use in sunscreen formulations. Then, the concomitant use of both was described from a historical and physical chemical perspective, always emphasizing the advantages and disadvantages of this association.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>The combination of antioxidants with UV-B filter octylmethoxycinnamate in appropriated formulations represents a viable strategy to protect the human skin against UV-induced damage.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s41702-019-0048-9","type":"journal-article","created":{"date-parts":[[2019,12,24]],"date-time":"2019-12-24T00:02:49Z","timestamp":1577145769000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":35,"title":["Antioxidants as stabilizers of UV filters: an example for the UV-B filter octylmethoxycinnamate"],"prefix":"10.1186","volume":"3","author":[{"given":"Margarida","family":"Lorigo","sequence":"first","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4823-5701","authenticated-orcid":false,"given":"Elisa","family":"Cairrao","sequence":"additional","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2019,12,24]]},"reference":[{"key":"48_CR1","doi-asserted-by":"publisher","first-page":"356","DOI":"10.1590\/abd1806-4841.20175697","volume":"92","author":"Addor FASa","year":"2017","unstructured":"Addor FASa. 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