{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T13:57:35Z","timestamp":1781704655181,"version":"3.54.5"},"reference-count":19,"publisher":"Oncology Nursing Society (ONS)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["CJON"],"published-print":{"date-parts":[[2015,2,1]]},"DOI":"10.1188\/15.cjon.e8-e14","type":"journal-article","created":{"date-parts":[[2015,2,11]],"date-time":"2015-02-11T16:44:01Z","timestamp":1423673041000},"page":"E8-E14","source":"Crossref","is-referenced-by-count":11,"title":["Preventive Measures for Cyclophosphamide-Related Hemorrhagic Cystitis in Blood and Bone Marrow Transplantation: An Italian Multicenter Retrospective Study"],"prefix":"10.1188","volume":"19","author":[{"given":"Silvia","family":"Gonella","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tania","family":"di Pasquale","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alvisa","family":"Palese","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1302","published-online":{"date-parts":[[2015,1,30]]},"reference":[{"key":"1","unstructured":"Atkinson, K., Biggs, J.C., Golovsky, D., Concannon, A., Dodds, A., Downs, K., & Ashby, M. (1991). Bladder irrigation does not prevent haemorrhagic cystitis in bone marrow transplant recipients. Bone Marrow Transplantation, 7, 351\u2013354."},{"key":"2","doi-asserted-by":"crossref","unstructured":"Bedi, A., Miller, C.B., Hanson, J.L., Goodman, S., Ambinder, R.F., Charache, P., . . . Jones, R.L. (1995). Association of BK virus with failure of prophylaxis against hemorrhagic cystitis following bone marrow transplantation. Journal of Clinical Oncology, 13, 1103\u20131109.","DOI":"10.1200\/JCO.1995.13.5.1103"},{"key":"3","doi-asserted-by":"crossref","unstructured":"Dobrek, L., & Thor, P.J. (2012). Bladder urotoxicity pathophysiology induced by the oxazaphosphorine alkylating agents and its chemoprevention. Postepy Higieny i Medycyny Doswiadczalnej, 66, 592\u2013602.","DOI":"10.5604\/17322693.1009703"},{"key":"4","doi-asserted-by":"crossref","unstructured":"El-Zimaity, M., Saliba, R., Chan, K., Shahjahan, M., Carrasco, A., Khorshid, O., . . . de Lima, M. (2004). Hemorrhagic cystitis after allogeneic hematopoietic stem cell transplantation: Donor type matters. Blood, 103, 4674\u20134680. doi:10.1182\/blood-2003-08-2815","DOI":"10.1182\/blood-2003-08-2815"},{"key":"5","doi-asserted-by":"crossref","unstructured":"Erard, V., Kim, H.W., Corey, L., Limaye, A., Huang, M.L., Myerson, D., . . . Boeckh, M. (2005). BK DNA viral load in plasma: Evidence for an association with hemorrhagic cystitis in allogeneic hematopoietic cell transplant recipients. Blood, 106, 1130\u20131132. doi:10.1182\/blood-2004-12-4988","DOI":"10.1182\/blood-2004-12-4988"},{"key":"6","doi-asserted-by":"crossref","unstructured":"Fu, H., Xu, L., Liu, D., Zhang, X., Liu, K., Chen, H., . . . Huang, X. (2013). Late-onset hemorrhagic cystitis after haploidentical hematopoietic stem cell transplantation in patients with advanced leukemia: Differences in ATG dosage are key. International Journal of Hematology, 98, 89\u201395. doi:10.1007\/s12185-013-1350-8","DOI":"10.1007\/s12185-013-1350-8"},{"key":"7","doi-asserted-by":"crossref","unstructured":"Hadjibabaie, M., Alimoghaddam, K., Shamshiri, A.D., Iravani, M., Bahar, B., Mousavi, A., . . . Ghavamzadeh, A. (2008). Continuous bladder irrigation prevents hemorrhagic cystitis after allogenic hematopoietic cell transplantation. Urologic Oncology, 26, 43\u201346. doi:10.1016\/j.urolonc.2006.12.015","DOI":"10.1016\/j.urolonc.2006.12.015"},{"key":"8","doi-asserted-by":"crossref","unstructured":"Hassan, Z., Remberger, M., Svenberg, P., Elbander, M., Omazic, B., Mattsson, J., . . . Ringd\u00e9n, O. (2007). Hemorrhagic cystitis: A retrospective single-center survey. Clinical Transplantation, 21, 659\u2013667. doi:10.1111\/j.1399-0012.2007.00705.x","DOI":"10.1111\/j.1399-0012.2007.00705.x"},{"key":"9","doi-asserted-by":"crossref","unstructured":"Hensley, M.L., Hagerty, K.L., Kewalramani, T., Green, D.M., Meropol, N.J., Wasserman, T.H., . . . Schuchter, L.M. (2009). American Society of Clinical Oncology 2008 clinical practice guideline update: Use of chemotherapy and radiation therapy protectants. Journal of Clinical Oncology, 27, 127\u2013145.","DOI":"10.1200\/JCO.2008.17.2627"},{"key":"10","doi-asserted-by":"crossref","unstructured":"Korkmaz, A., Topal, T., & Oter, S. (2007). Pathophysiological aspects of cyclophosphamide and ifosfamide induced hemorrhagic cystitis; implication of reactive oxygen and nitrogen species as well as PARP activation. Cell Biology and Toxicology, 23, 303\u2013312.","DOI":"10.1007\/s10565-006-0078-0"},{"key":"11","doi-asserted-by":"crossref","unstructured":"Lee, G.W., Lee, J.H., Choi, S.J., Kim, S., Seol, M., Kim, W.K., . . . Lee, K.H. (2003). Hemorrhagic cystitis following allogeneic hematopoietic cell transplantation. Journal of Korean Medical Science, 18, 191\u2013195.","DOI":"10.3346\/jkms.2003.18.2.191"},{"key":"12","doi-asserted-by":"crossref","unstructured":"Leung, A.Y., Mak, R., Lie, A.K., Yuen, K.Y., Cheng, V.C., Liang, R., & Kwong, Y.L. (2002). Clinicopathological features and risk factors of clinically overt haemorrhagic cystitis complicating bone marrow transplantation. Bone Marrow Transplantation, 29, 509\u2013513. doi:10.1038\/sj.bmt.1703415","DOI":"10.1038\/sj.bmt.1703415"},{"key":"13","doi-asserted-by":"crossref","unstructured":"Miller, A.N., Glode, A., Hogan, K.R., Schaub, C., Kramer, C., Stuart, R.K., & Costa, L.J. (2011). Efficacy and safety of ciprofloxacin for prophylaxis of polyomavirus BK virus-associated hemorrhagic cystitis in allogeneic hematopoietic stem cell transplantation recipients. Biology of Blood and Marrow Transplantation, 17, 1176\u20131181. doi:10.1016\/j.bbmt.2010.12.700","DOI":"10.1016\/j.bbmt.2010.12.700"},{"key":"14","unstructured":"Russell, S.J., Vowels, M.R., & Vale, T. (1994). Haemorragic cystitis in paediatric bone marrow transplant patients: An association with infective agents, GVHD, and prior cyclophosphamide. Bone Marrow Transplantation, 13, 533\u2013539."},{"key":"15","doi-asserted-by":"crossref","unstructured":"Shepherd, J.D., Pringle, L.E., Barnett, M.J., Klingemann, H.G., Reece, D.E., & Phillips, G.L. (1991). Mesna versus hyperhydration for the prevention of cyclophosphamide-induced hemorrhagic cystitis in bone marrow transplantation. Journal of Clinical Oncology, 9, 2016\u20132020.","DOI":"10.1200\/JCO.1991.9.11.2016"},{"key":"16","doi-asserted-by":"crossref","unstructured":"Tsuboi, K., Kishi, K., Ohmachi, K., Yasuda, Y., Shimizu, T., Inoue, H., . . . Hotta, T. (2003). Multivariate analysis of risk factors for hemorrhagic cystitis after hematopoietic stem cell transplantation. Bone Marrow Transplantation, 32, 903\u2013907.","DOI":"10.1038\/sj.bmt.1704240"},{"key":"17","doi-asserted-by":"crossref","unstructured":"Turkeri, L.N., Lum, L.G., Uberti, J.P., Abella, E., Momin, F., Karanes, C., . . . Haas, G.P. (1995). Prevention of hemorrhagic cystitis following allogeneic bone marrow transplant preparative regimens with cyclophosphamide and busulfan: Role of continuous bladder irrigation. Journal of Urology, 153, 637\u2013640.","DOI":"10.1016\/S0022-5347(01)67670-5"},{"key":"18","doi-asserted-by":"crossref","unstructured":"Vose, J.M., Reed, E.C., Pippert, G.C., Anderson, J.R., Bierman, P.J., Kessinger, A., . . . Armitage, J.O. (1993). Mesna compared with continuous bladder irrigation as uroprotection during high-dose chemotherapy and transplantation: A randomized trial. Journal of Clinical Oncology, 11, 1306\u20131310.","DOI":"10.1200\/JCO.1993.11.7.1306"},{"key":"19","doi-asserted-by":"crossref","unstructured":"Xu, L., Zhang, H., Huang, X.J., Liu, K.Y., Liu, D.H., Han, W., . . . Lu, D.P. (2007). Hemorrhagic cystitis following hematopoietic stem cell transplantation: Incidence, risk factors and association with CMV reactivation and graft-versus-host-disease. Chinese Medical Journal, 120, 1666\u20131671.","DOI":"10.1097\/00029330-200710010-00004"}],"container-title":["Clinical Journal of Oncology Nursing"],"original-title":[],"link":[{"URL":"http:\/\/cjon.ons.org\/cjon\/19\/1\/preventive-measures-cyclophosphamide-related-hemorrhagic-cystitis-blood-and-bone-marrow","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T19:53:32Z","timestamp":1763754812000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ons.org\/publications-research\/cjon\/19\/1\/preventive-measures-cyclophosphamide-related-hemorrhagic-cystitis"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,1,30]]},"references-count":19,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2015,2,1]]}},"URL":"https:\/\/doi.org\/10.1188\/15.cjon.e8-e14","relation":{},"ISSN":["1092-1095","1538-067X"],"issn-type":[{"value":"1092-1095","type":"print"},{"value":"1538-067X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,1,30]]}}}