{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T20:05:00Z","timestamp":1763755500220,"version":"3.45.0"},"reference-count":16,"publisher":"Oncology Nursing Society (ONS)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ONF"],"published-print":{"date-parts":[[2015,3,1]]},"DOI":"10.1188\/15.onf.200-203","type":"journal-article","created":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T13:29:46Z","timestamp":1441114186000},"page":"200-203","source":"Crossref","is-referenced-by-count":0,"title":["Richter Syndrome: An Aggressive Transformation"],"prefix":"10.1188","volume":"42","author":[{"given":"Erin","family":"Streu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1302","published-online":{"date-parts":[[2015,2,28]]},"reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"Ansell, S.M., Li, C.Y., Lloyd, R.V., & Phyliky, R.L. (1999). Epstein-Barr infection in Richter\u2019s transformation. American Journal of Hematology, 60, 99\u2013104.","DOI":"10.1002\/(SICI)1096-8652(199902)60:2<99::AID-AJH3>3.0.CO;2-T"},{"key":"2","doi-asserted-by":"crossref","unstructured":"Conte, M.J., Bowen, D., Wiseman, G.A., Rabe, K.G., Slager, S.L., Shwager, S., . . . Zent, C.S. (2014). Use of positron emission tomography-computed tomography in the management of patients with chronic lymphocytic leukemia\/small lymphocytic lymphoma. Leukemia and Lymphoma, 55, 2079\u20132084.","DOI":"10.3109\/10428194.2013.869801"},{"key":"3","doi-asserted-by":"crossref","unstructured":"Falchi, L., Keating, M.J., Marom, E., Truong, T., Schlette, E., Sargent, R., . . . Ferrajoli, A. (2014). Correlation between FDG\/PET, histology, characteristics, and survival in 332 patients with chronic lymphoid leukemia. Blood, 123, 2783\u20132790.","DOI":"10.1182\/blood-2013-11-536169"},{"key":"4","unstructured":"Jain, P., & O\u2019Brien, S. (2012). Richter\u2019s transformation in chronic lymphocytic leukemia. Oncology (Williston Park), 26, 1146\u20131152."},{"key":"5","unstructured":"Lortholary, P., Boiron, M., Ripault, P., Levy, J.P., Manus, A., & Bernard, J. (1964). [Chronic lymphoid leukemia secondarily associated with a malignant reticulopathy: Richter\u2019s syndrome.] Nouvelle Revue Francaise d\u2019Hematologie, 4, 621\u2013644."},{"key":"6","doi-asserted-by":"crossref","unstructured":"Maddocks-Christianson, K., Slager, S., Zent, C., Reinalda, N., Call, T., Habermann, T., . . . Shanafelt, T.D. (2007). Risk factors for development of a second lymphoid malignancy in patients with chronic lymphocytic leukaemia. British Journal of Hematology, 139, 398\u2013404.","DOI":"10.1111\/j.1365-2141.2007.06801.x"},{"key":"7","doi-asserted-by":"crossref","unstructured":"Parikh, S.A., Kay, N.E., & Shanafelt, T.D. (2014). How we treat Richter syndrome. Blood, 123, 1647\u20131657.","DOI":"10.1182\/blood-2013-11-516229"},{"key":"8","doi-asserted-by":"crossref","unstructured":"Parikh, S., Rabe, K., Call, C., Zent, C., Habermann, T., Ding, W., Leis, J., . . . Shanafelt, T.D. (2013). Diffuse large B-cell lymphoma (Richter syndrome) in patients with chronic lymphocytic leukaemia (CLL): A cohort study of newly diagnosed patients. British Journal of Hematology, 162, 774\u2013782.","DOI":"10.1111\/bjh.12458"},{"key":"9","doi-asserted-by":"crossref","unstructured":"Rossi, D., Cerri, M., Capello, D., Deambrogi, C., Rossi, F., Zucchetto, A., . . . Gaidano, G. (2008). Biological and clinical risk factors of chronic lymphocytic leukaemia transformation to Richter syndrome. British Journal of Hematology, 142, 202\u2013215.","DOI":"10.1111\/j.1365-2141.2008.07166.x"},{"key":"10","doi-asserted-by":"crossref","unstructured":"Rossi, D., & Gaidano, G. (2013). Richter syndrome. Advances in Experimental Medicine and Biology, 792, 173\u2013191.","DOI":"10.1007\/978-1-4614-8051-8_8"},{"key":"11","doi-asserted-by":"crossref","unstructured":"Rossi, D., Rasi, S., Spina, V., Fangazio, M., Monti, S., Greco, M., . . . Gaidano, G. (2012). Different impact of NOTCH1 and SF3B1 mutations on the risk of chronic lymphocytic leukemia transformation to Richter syndrome. British Journal of Hematology, 158, 426\u2013429.","DOI":"10.1111\/j.1365-2141.2012.09155.x"},{"key":"12","doi-asserted-by":"crossref","unstructured":"Timar, B., F\u00fcl\u00f6p, Z., Csernus, B., Angster, C., Bognar, A., Szepesi, A., . . . Matolcsy, A. (2004). Relationship between the mutational status of VH genes and pathogenesis of diffuse large B-cell lymphoma in Richter\u2019s syndrome. Leukemia, 18, 326\u2013330.","DOI":"10.1038\/sj.leu.2403249"},{"key":"13","doi-asserted-by":"crossref","unstructured":"Tsimberidou, A.M., & Keating, M.J. (2005). Richter syndrome. Biology, incidence, and therapeutic strategies. Cancer, 103, 216\u2013228.","DOI":"10.1002\/cncr.20773"},{"key":"14","doi-asserted-by":"crossref","unstructured":"Tsimberidou, A.M., O\u2019Brien, S., Khouri, I., Giles, F., Kantarijan, H.M., Champlin, R., . . . Keating, M.J. (2006). Clinical outcomes and prognostic factors in patients with Richter\u2019s syndrome treated with chemotherapy or chemoimmunotherapy with or without stem-cell transplantation. Journal of Clinical Oncology, 24, 2343\u20132351.","DOI":"10.1200\/JCO.2005.05.0187"},{"key":"15","doi-asserted-by":"crossref","unstructured":"Tsimberidou, A.M., Wierda, W.G., Wen, S., Plunkett, W., O\u2019Brien, S., Kipps, T.J., . . . Keating, M.J. (2013). Phase I\u2013II clinical trial of oxaliplatin, fludarabine, cytarabine, and rituximab therapy in aggressive relapsed\/refractory chronic lymphocytic leukemia or Richter\u2019s syndrome. Clinical Lymphoma, Myeloma and Leukemia, 13, 568\u2013574.","DOI":"10.1016\/j.clml.2013.03.012"},{"key":"16","doi-asserted-by":"crossref","unstructured":"Wilson, W.H., Gerecitano, J.F., Goy, A., de Vos, S., Kenkre, M.D., Barr, P.D., . . . Staudt, L.M. (2012). The Bruton\u2019s tyrosine kinase (BTK) inhibitor, ibrutinib, (PCI-32765), has preferential activity in the ABC subtype of relapsed\/refractory de novo diffuse large B-cell lymphoma (DLBCL): Interim results of a multi-center, open label, phase 2 study [Abstract 686]. Retrieved from https:\/\/ash\u2028.confex.com\/ash\/2012\/webprogram\/Paper48270.html","DOI":"10.1182\/blood.V120.21.686.686"}],"container-title":["Oncology Nursing Forum"],"original-title":[],"link":[{"URL":"http:\/\/onf.ons.org\/onf\/42\/2-0\/richter-syndrome-aggressive-transformation","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T19:53:28Z","timestamp":1763754808000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ons.org\/publications-research\/onf\/42\/2\/richter-syndrome-aggressive-transformation"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,2,28]]},"references-count":16,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2015,3,1]]}},"URL":"https:\/\/doi.org\/10.1188\/15.onf.200-203","relation":{},"ISSN":["0190-535X","1538-0688"],"issn-type":[{"type":"print","value":"0190-535X"},{"type":"electronic","value":"1538-0688"}],"subject":[],"published":{"date-parts":[[2015,2,28]]}}}