{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T01:49:10Z","timestamp":1762998550966,"version":"3.37.3"},"reference-count":48,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2006,2,24]],"date-time":"2006-02-24T00:00:00Z","timestamp":1140739200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"DOI":"10.13039\/501100004359","name":"Swedish Research Council","doi-asserted-by":"publisher","award":["K2004-16X-12615-07A"],"award-info":[{"award-number":["K2004-16X-12615-07A"]}],"id":[{"id":"10.13039\/501100004359","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007687","name":"Swedish Society of Medicine","doi-asserted-by":"publisher","award":["2003-633"],"award-info":[{"award-number":["2003-633"]}],"id":[{"id":"10.13039\/501100007687","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Tobias Foundation","award":["33\/02","28\/03"],"award-info":[{"award-number":["33\/02","28\/03"]}]},{"name":"Swedish Children Cancer Research Foundation","award":["PROJ01\/046"],"award-info":[{"award-number":["PROJ01\/046"]}]},{"name":"Emil and Wera Cornells Foundation"},{"name":"Heart and Lung Foundation","award":["20030830"],"award-info":[{"award-number":["20030830"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2006,2,24]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Dendritic cells (DCs) are important target cells for human cytomegalovirus (HCMV) infection, and the virus has been shown to hamper the differentiation and maturation pathways of these cells in vitro. In the present study, we examined the function of monocyte-derived DCs obtained from immunocompetent individuals undergoing symptomatic HCMV infection in terms of immunophenotypic characteristics, pinocytosis, lymphocyte stimulation capacity, and cyto-chemokine secretion in comparison with DCs obtained from healthy controls. Immature and lipopolysaccharide (LPS)-stimulated DCs obtained from patients actively infected with HCMV expressed significantly lower levels of major histocompatibility complex (MHC) class II molecules. The inhibition of expression of MHC class II molecules by HCMV appeared to be functionally relevant, as mature DCs obtained from patients with HCMV mononucleosis were inefficient in stimulating proliferation of allogenic lymphocytes. Finally, the pattern of cyto-chemokines secreted by DCs obtained from patients with HCMV mononucleosis was characterized by a proinflammatory profile with an increased production of interleukin (IL)-1\u03b2, tumor necrosis factor \u03b1, CC chemokine ligand 2 (CCL2) and CCL3, and reduced secretion of IL-10 upon LPS stimulation. During symptomatic HCMV infection in the immunocompetent host, DCs exhibit an impaired immunophenotype and function. These effects may contribute to the viral-induced immunomodulation, which is often observed in HCMV-infected patients.<\/jats:p>","DOI":"10.1189\/jlb.0905499","type":"journal-article","created":{"date-parts":[[2006,2,25]],"date-time":"2006-02-25T01:45:05Z","timestamp":1140831905000},"page":"932-940","source":"Crossref","is-referenced-by-count":19,"title":["Dendritic cell function in cytomegalovirus-infected patients with mononucleosis"],"prefix":"10.1093","volume":"79","author":[{"given":"Giada","family":"Frascaroli","sequence":"first","affiliation":[{"name":"Department of Clinical and Experimental Medicine, Section of Microbiology, University of Boogna , Italy"},{"name":"Department of Virology, University of Ulm , Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefania","family":"Varani","sequence":"additional","affiliation":[{"name":"Department of Clinical and Experimental Medicine, Section of Microbiology, University of Boogna , Italy"},{"name":"Center for Molecular Medicine , Stockholm, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio","family":"Mastroianni","sequence":"additional","affiliation":[{"name":"Unit of Infectious Diseases, \u201cG.B. Morgagni\u201d General Hospital , Forl\u00ec, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sven","family":"Britton","sequence":"additional","affiliation":[{"name":"Unit of Infectious Diseases, Department of Medicine, Karolinska Institutet , Stockholm, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Davide","family":"Gibellini","sequence":"additional","affiliation":[{"name":"Department of Clinical and Experimental Medicine, Section of Microbiology, University of Boogna , Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giada","family":"Rossini","sequence":"additional","affiliation":[{"name":"Department of Clinical and Experimental Medicine, Section of Microbiology, University of Boogna , Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria P","family":"Landini","sequence":"additional","affiliation":[{"name":"Department of Clinical and Experimental Medicine, Section of Microbiology, University of Boogna , Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cecilia","family":"S\u00f6derberg-Naucl\u00e9r","sequence":"additional","affiliation":[{"name":"Center for Molecular Medicine , Stockholm, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2006,2,24]]},"reference":[{"key":"2023033015235110100_jlb0932-cit-B1","first-page":"2675","volume-title":"Fields Virology","author":"Pass","year":"2001"},{"key":"2023033015235110100_jlb0932-cit-B2","first-page":"207","volume-title":"Viral Pathogenesis","author":"Griffin","year":"1996"},{"key":"2023033015235110100_jlb0932-cit-B3","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1086\/338624","article-title":"High risk of death due to bacterial and fungal infection among cytomegalovirus (CMV)-seronegative recipients of stem cell transplants from seropositive donors: evidence for indirect effects of primary CMV infection","volume":"185","author":"Nichols","year":"2002","journal-title":"J. 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Biol."},{"key":"2023033015235110100_jlb0932-cit-B32","doi-asserted-by":"crossref","first-page":"1233","DOI":"10.1002\/(SICI)1521-4141(200004)30:4<1233::AID-IMMU1233>3.0.CO;2-F","article-title":"Differential effects of corticosteroids during different stages of dendritic cell maturation","volume":"30","author":"Matyszak","year":"2000","journal-title":"Eur. J. Immunol."},{"key":"2023033015235110100_jlb0932-cit-B33","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1086\/314939","article-title":"Asymptomatic primary cytomegalovirus infection: virologic and immunologic features","volume":"180","author":"Zanghellini","year":"1999","journal-title":"J. Infect. Dis."},{"key":"2023033015235110100_jlb0932-cit-B34","doi-asserted-by":"crossref","first-page":"4207","DOI":"10.1182\/blood-2003-12-4350","article-title":"Infection of mature monocyte-derived dendritic cells with human cytomegalovirus inhibits stimulation of T-cell proliferation via the release of soluble CD83","volume":"103","author":"Senechal","year":"2004","journal-title":"Blood"},{"key":"2023033015235110100_jlb0932-cit-B35","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1097\/01.TP.0000146589.49756.7F","article-title":"Augmentation of type-1 polarizing ability of monocyte-derived dendritic cells from chronically immunosuppressed organ-transplant recipients","volume":"79","author":"Macedo","year":"2005","journal-title":"Transplantation"},{"key":"2023033015235110100_jlb0932-cit-B36","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1038\/79758","article-title":"Kinetics of dendritic cell activation: impact on priming of TH1, TH2 and nonpolarized T cells","volume":"1","author":"Langenkamp","year":"2000","journal-title":"Nat. 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Virol."},{"key":"2023033015235110100_jlb0932-cit-B39","doi-asserted-by":"crossref","first-page":"3154","DOI":"10.1172\/JCI119871","article-title":"Interferon-\u03b3 and tumor necrosis factor-\u03b1 specifically induce formation of cytomegaloviruspermissive monocyte-derived macrophages that are refractory to the antiviral activity of these cytokines","volume":"100","author":"Soderberg-Naucler","year":"1997","journal-title":"J. Clin. Invest."},{"key":"2023033015235110100_jlb0932-cit-B40","doi-asserted-by":"crossref","first-page":"2635","DOI":"10.1172\/JCI118713","article-title":"Human cytomegalovirus-induced immunosuppression. Relationship to tumor necrosis factor-dependent release of arachidonic acid and prostaglandin E2 in human monocytes","volume":"97","author":"Nokta","year":"1996","journal-title":"J. Clin. 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Virol."},{"key":"2023033015235110100_jlb0932-cit-B43","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1086\/315184","article-title":"The role of the tumor necrosis factor system and interleukin-10 during cytomegalovirus infection in renal transplant recipients","volume":"181","author":"Nordoy","year":"2000","journal-title":"J. Infect. Dis."},{"key":"2023033015235110100_jlb0932-cit-B44","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1097\/00130832-200312000-00008","article-title":"Chemokine regulation of inflammation during acute viral infection","volume":"3","author":"Glass","year":"2003","journal-title":"Curr. Opin. Allergy Clin. Immunol."},{"key":"2023033015235110100_jlb0932-cit-B45","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1189\/jlb.1102577","article-title":"Expression and function of chemokines during viral infections: from molecular mechanisms to in vivo function","volume":"74","author":"Melchjorsen","year":"2003","journal-title":"J. Leukoc. 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