{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T20:29:52Z","timestamp":1777667392989,"version":"3.51.4"},"reference-count":23,"publisher":"SAGE Publications","issue":"12","license":[{"start":{"date-parts":[[1999,12,1]],"date-time":"1999-12-01T00:00:00Z","timestamp":944006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Hum Exp Toxicol"],"published-print":{"date-parts":[[1999,12]]},"abstract":"<jats:p>\n                    1 Adult male albino rats (CF Strain) were administered i.p. CS\n                    <jats:sub>2<\/jats:sub>\n                    dissolved in cotton seed oil at doses of 25, 50, 100 and 200 mg\/kg b.wt. for a period of 60 days. Effect of CS, on epididymis, adrenal weight, sperm count and sperm head shape abnormality was studied. 2 Epididymal weight remained unaltered in 25, 50 and 100 mg\/kg CS\n                    <jats:sub>2<\/jats:sub>\n                    treated groups, whereas in highest dose of CS\n                    <jats:sub>2<\/jats:sub>\n                    treated (200 mg\/kg) group a non-significant reduction in epididymis weight was observed. A slight increase in adrenal weight was observed in lower doses groups (25 and 50 mg\/kg) while a considerable decrease in adrenal weight was noted in highest dose (200 mg\/kg) of CS, treated group in the present study. 3 An increase in sperm head shape abnormality and decrease in sperm count was observed in all the CS\n                    <jats:sub>2<\/jats:sub>\n                    treated groups. However, the changes were statistically significant only after higher dose of CS\n                    <jats:sub>2<\/jats:sub>\n                    treatment as compared to control. 4 This study suggests that CS\n                    <jats:sub>2<\/jats:sub>\n                    may have the potential to induce adverse effects on male reproductive system of rats. Sperm head shape abnormality assay used in this study also elicits germ cell genotoxic potential of carbon disulphide.\n                  <\/jats:p>","DOI":"10.1191\/096032799678839608","type":"journal-article","created":{"date-parts":[[2003,4,3]],"date-time":"2003-04-03T19:38:43Z","timestamp":1049398723000},"page":"731-734","source":"Crossref","is-referenced-by-count":5,"title":["Detection of germ cell genotoxic potential, of carbon disuiphide using sperm                 head shape abnormality test"],"prefix":"10.1177","volume":"18","author":[{"given":"S","family":"Kumar","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K G","family":"Patel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A K","family":"Gautam","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K","family":"Agarwal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B A","family":"Shah","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H N","family":"Saiyed","sequence":"additional","affiliation":[{"name":"Division of Reproductive Toxicology, National Institute of Occupational                         Health, Meghani Nagar, Ahmedabad 380016, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1999,12,1]]},"reference":[{"key":"atypb1","unstructured":"1                      WHO                 : Carbon disulphide.                      Environmental health criteria. Geneva, Switzerland                 , 1979; pp. 11-75."},{"key":"atypb2","first-page":"743","volume-title":"Krik-othmer encyclopedia of chemical technology","author":"Timmerman RW","year":"1978","edition":"3"},{"key":"atypb3","unstructured":"3 The Merck Index, 10th edn. Windholz M                  (ed)                      Merck and Co, Inc., Merck Research Laboratories,                         Rahway, New Jersey                 , 1983; p. 251-251."},{"key":"atypb4","first-page":"1","volume-title":"US Department of Health and Human Services","year":"1992"},{"key":"atypb5","doi-asserted-by":"publisher","DOI":"10.1007\/BF00685252"},{"key":"atypb6","first-page":"53","volume":"4","author":"Johnson BL","year":"1983","journal-title":"Neurotoxicology"},{"key":"atypb7","first-page":"533","volume":"8","author":"Robert CS","year":"1986","journal-title":"Neurobehav Toxicol Teratol"},{"key":"atypb8","doi-asserted-by":"publisher","DOI":"10.1016\/0041-008X(84)90333-8"},{"key":"atypb9","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.pa.25.040185.003031"},{"key":"atypb10","first-page":"24","volume":"38","author":"Vasiljeva IA","year":"1973","journal-title":"Gigi Sanit"},{"key":"atypb11","first-page":"535","volume":"38","author":"Finkova A","year":"1973","journal-title":"Cesk Gynekol"},{"key":"atypb12","doi-asserted-by":"publisher","DOI":"10.1016\/0300-483X(84)90033-7"},{"key":"atypb13","first-page":"257","volume-title":"Chemical mutagens: Principles and methods for their detection","author":"Wyrobek AJ","year":"1978"},{"key":"atypb14","doi-asserted-by":"publisher","DOI":"10.1016\/0304-3835(92)90021-M"},{"key":"atypb15","first-page":"29","volume":"63","author":"Lancranjan I","year":"1972","journal-title":"Med Lav"},{"key":"atypb16","first-page":"50","volume":"3","author":"Petrov MV","year":"1969","journal-title":"Pediatr Akush Ginekol"},{"key":"atypb17","first-page":"132","volume-title":"Principle and methods of toxicology","author":"Ayres Paul H","year":"1988"},{"key":"atypb18","doi-asserted-by":"publisher","DOI":"10.1080\/00028895909343722"},{"key":"atypb19","first-page":"22","volume":"53","author":"Patel KG","year":"1999","journal-title":"Indian J Physiol Allied Sci"},{"key":"atypb20","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.72.11.4425"},{"key":"atypb21","volume-title":"Teratogenic-mutagenic risks of workplace contaminants: Trichloroethylene, perchloroethylene and carbon disulfide","author":"NIOSH","year":"1980"},{"key":"atypb22","doi-asserted-by":"publisher","DOI":"10.1002\/tcm.1770100104"},{"key":"atypb23","doi-asserted-by":"publisher","DOI":"10.1016\/0003-4878(94)00128-N"}],"container-title":["Human &amp; Experimental Toxicology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1191\/096032799678839608","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1191\/096032799678839608","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T07:46:36Z","timestamp":1777448796000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1191\/096032799678839608"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1999,12]]},"references-count":23,"journal-issue":{"issue":"12","published-print":{"date-parts":[[1999,12]]}},"alternative-id":["10.1191\/096032799678839608"],"URL":"https:\/\/doi.org\/10.1191\/096032799678839608","relation":{},"ISSN":["0960-3271","1477-0903"],"issn-type":[{"value":"0960-3271","type":"print"},{"value":"1477-0903","type":"electronic"}],"subject":[],"published":{"date-parts":[[1999,12]]}}}