{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,16]],"date-time":"2025-05-16T18:22:41Z","timestamp":1747419761946,"version":"3.38.0"},"reference-count":12,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2000,5,1]],"date-time":"2000-05-01T00:00:00Z","timestamp":957139200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Lupus"],"published-print":{"date-parts":[[2000,5]]},"abstract":"<jats:p> The authors report the case of a 43-year-old woman suffering from severe systemic lupus erythematosus treated with long-term prednisone, who developed Nocardia nova infection on a hip prosthesis. Sepsis occurred about two years after an episode of pulmonary nocardiosis with the same Nocardia species, that was successfully treated by 12 months of antibiotics. A good outcome of the joint infection was observed in response to antibiotics and removal of the prosthesis. <\/jats:p><jats:p> Nocardiosis is a rare infection, acting as an opportunisticinfection, facilitated in the present case by systemic lupus erythematosus and chronic corticosteroid therapy. Nocardia infections mainly affect the lungs, skin and central nervous system; these last two sites are mostly due to haematogenous spread, a frequent event. Treatment is based on antibiotics, usually continued for 3 \u2010 12 months, especially because of the risk of relapse. The imipenem \u2010 amikacin combination appears to be more effective than trimethoprim \u2010 sulfamethoxazole. To our knowledge, this is the first case report of Nocardia nova joint prosthesis infection also presenting as late septic spread of pulmonary nocardiosis, complicating corticosteroid-treated systemic lupus erythematosus. <\/jats:p>","DOI":"10.1191\/096120300680198917","type":"journal-article","created":{"date-parts":[[2003,11,12]],"date-time":"2003-11-12T12:45:16Z","timestamp":1068641116000},"page":"304-306","source":"Crossref","is-referenced-by-count":13,"title":["Nocardia infection of a joint prosthesis complicating systemic lupus erythematosus"],"prefix":"10.1177","volume":"9","author":[{"given":"C","family":"Arnal","sequence":"first","affiliation":[{"name":"Service de M\u00e9decine Interne, H\u00f4pital Tenon, 4 rue                         de la Chine, F-75970, Paris Cedex 20, France.Tel: (\/33) (1) 56 01 66 14;                         Fax: (+33) (01) 70 82"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H","family":"Man","sequence":"additional","affiliation":[{"name":"Service de M\u00e9decine Interne, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F","family":"Delisle","sequence":"additional","affiliation":[{"name":"Laboratoire de Bact\u00e9riologie, H\u00f4pital Tenon,                         Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P","family":"M'Bappe","sequence":"additional","affiliation":[{"name":"Laboratoire de Bact\u00e9riologie, H\u00f4pital Tenon,                         Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J-J","family":"Cocheton","sequence":"additional","affiliation":[{"name":"Laboratoire de Bact\u00e9riologie, H\u00f4pital Tenon,                         Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2000,5,1]]},"reference":[{"key":"atypb1","first-page":"2273","volume-title":"Mandell, Douglas and Bennett's principles and practice of infectious diseases","author":"Lerner PI","year":"1995","edition":"4"},{"key":"atypb2","doi-asserted-by":"publisher","DOI":"10.1016\/S0049-0172(97)80003-0"},{"key":"atypb3","first-page":"657","volume":"50","author":"Frazier AR","year":"1975","journal-title":"Mayo Clin Proc"},{"key":"atypb4","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.7.3.357"},{"key":"atypb5","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/22.6.891"},{"key":"atypb6","unstructured":"Boiron P. Actinomyce\u00c1tes a\u00e9robies. Rapport                 d'activit\u00e9 du Centre National de R\u00e9f\u00e9rence                 des mycoses humaines, des antifongiques et des actinomyce\u00c1tes.                 Unit\u00e9 de mycologie, Institut Pasteur, Paris, 1998."},{"key":"atypb7","doi-asserted-by":"publisher","DOI":"10.1097\/00000441-198009000-00009"},{"key":"atypb8","first-page":"271","volume":"74","author":"Wongthim S","year":"1991","journal-title":"J Med Assoc Thai"},{"key":"atypb9","first-page":"107","volume":"49","author":"Robinson D","year":"1989","journal-title":"Bull Hosp Jt Dis Orthop Inst"},{"key":"atypb10","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1992.46.141"},{"key":"atypb11","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/4.2.315"},{"key":"atypb12","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.29.11.2407-2411.1991"}],"container-title":["Lupus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1191\/096120300680198917","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1191\/096120300680198917","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T10:26:23Z","timestamp":1740824783000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1191\/096120300680198917"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,5]]},"references-count":12,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2000,5]]}},"alternative-id":["10.1191\/096120300680198917"],"URL":"https:\/\/doi.org\/10.1191\/096120300680198917","relation":{},"ISSN":["0961-2033","1477-0962"],"issn-type":[{"type":"print","value":"0961-2033"},{"type":"electronic","value":"1477-0962"}],"subject":[],"published":{"date-parts":[[2000,5]]}}}