{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T10:05:54Z","timestamp":1770977154863,"version":"3.50.1"},"reference-count":24,"publisher":"SAGE Publications","issue":"7","license":[{"start":{"date-parts":[[2003,7,1]],"date-time":"2003-07-01T00:00:00Z","timestamp":1057017600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Lupus"],"published-print":{"date-parts":[[2003,7]]},"abstract":"<jats:p> Antiphospholipid Syndrome (APS) has been widely recognized as a risk factor for the recurrence of both thrombosis and pregnancy losses; however the optimal treatment of patients is debatable. The aim of this paper was to establish a consensus among experts on the treatment of APS in pregnancy. A questionnaire that described possible different clinical situations was sent to the International Advisory Board of the 10th International Congress on AntiphospholipidAntibodies. Sixteen experts from different medical branches and different geographic areas sent their replies. The consensus was that treatment for APS pregnant patients should be low molecular weight heparin (LMWH) and low dose aspirin (LDA). The dosage, and frequency of LMWH depends on different situations, including the body weight and past history. Patients with previous thromboses usually receive two injections per day. Warfarin can also be used from 14 to 34 weeks, for patients with previousstroke or severe arterial thromboses. The use of intravenous immunoglobulin (IVIG) seems to be restricted to patients with pregnancy losses despite conventional treatment. The experts usually advised barrier methods of contraception, intrauterine device (if the patient is not taking corticosteroids) or progestins. Oral contraception with oestrogens was usually avoided. <\/jats:p>","DOI":"10.1191\/0961203303lu393oa","type":"journal-article","created":{"date-parts":[[2003,7,14]],"date-time":"2003-07-14T22:53:15Z","timestamp":1058223195000},"page":"524-529","source":"Crossref","is-referenced-by-count":90,"title":["Treatment of pregnant patients with antiphospholipid syndrome"],"prefix":"10.1177","volume":"12","author":[{"given":"A","family":"Tincani","sequence":"first","affiliation":[{"name":"Rheumatology Allergy and Clinical Immunology, Brescia Hospital, Brescia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W","family":"Branch","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, University of Utah Health                         Science Center, Salt Lake City, Utah, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R A","family":"Levy","sequence":"additional","affiliation":[{"name":"Discipline of Rheumatology, Faculdade de Ciencias Medicas, Universidade                         do Estado do Rio de Janeiro, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J C","family":"Piette","sequence":"additional","affiliation":[{"name":"Department Internal Medicine, Hopital de la Piti\u00e9, Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H","family":"Carp","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Sheba Medical Center,                         Tel-Hashomer, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R S","family":"Rai","sequence":"additional","affiliation":[{"name":"Department of Reproductive Science and Medicine, Imperial College School                         of Medicine at St Mary\u2019s Mint Wing, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Khamashta","sequence":"additional","affiliation":[{"name":"Lupus Research Unit, Rayne 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