{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T01:54:34Z","timestamp":1792029274350,"version":"4.4.0"},"reference-count":75,"publisher":"SAGE Publications","issue":"12","license":[{"start":{"date-parts":[[2004,12,1]],"date-time":"2004-12-01T00:00:00Z","timestamp":1101859200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Lupus"],"published-print":{"date-parts":[[2004,12]]},"abstract":"<jats:p>\n                    The acute clinical syndrome of toxic epidermal necrolysis (TEN) is currently thought                 to be a distinct clinical-pathological entity typically resulting from drug                 hypersensitivity. We describe an adult woman who experienced a fulminate pattern of                 apoptotic epidermal cell injury following tanning bed exposure while taking naproxen                 that resulted in a clinical presentation having combined features of drug-induced                 TEN and an infrequently recognized form of bullous cutaneous lupus erythematosus                 (LE). This case calls attention to the fact that TEN-like injury can occasionally be                 seen in settings other than drug hypersensitivity (e.g., LE, acute graft versus host                 disease) and illustrates the need for a unifying concept in this area. We therefore                 propose the term \u2018\n                    <jats:underline>A<\/jats:underline>\n                    cute\n                    <jats:underline>S<\/jats:underline>\n                    yndrome of\n                    <jats:underline>A<\/jats:underline>\n                    poptotic\n                    <jats:underline>P<\/jats:underline>\n                    an-Epidermolysis (ASAP)\u2019 to designate a clinical syndrome that                 is characterized by life-threatening acute and massive cleavage of the epidermis                 resulting from hyperacute apoptotic injury of the epidermis. We also review                 vesiculobullous skin disorders that can be encountered in LE patients and suggest a                 new classification scheme for such lesions.\n                  <\/jats:p>","DOI":"10.1191\/0961203304lu2037sa","type":"journal-article","created":{"date-parts":[[2004,12,1]],"date-time":"2004-12-01T18:25:31Z","timestamp":1101925531000},"page":"941-950","source":"Crossref","is-referenced-by-count":122,"title":["Toxic epidermal necrolysis-like acute cutaneous lupus erythematosus and the                 spectrum of the acute syndrome of apoptotic pan-epidermolysis (ASAP): a case report,                 concept review and proposal for new classification of lupus erythematosus                 vesiculobullous skin lesions"],"prefix":"10.1177","volume":"13","author":[{"given":"W","family":"Ting","sequence":"first","affiliation":[{"name":"Department of Dermatology Camino Medical Group, Sunnyvale, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M S","family":"Stone","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Pathology, University of Iowa, Roy J and                         Lucille A Carver College of Medicine, IA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D","family":"Racila","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Pathology, University of Iowa, Roy J and                         Lucille A Carver College of Medicine, IA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R H","family":"Scofield","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of Oklahoma Health Science Center,                         Arthritis and Immunology Program, Oklahoma Medical Research Foundation, OK, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R D","family":"Sontheimer","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Pathology, University of Iowa, Roy J and                         Lucille A Carver College of Medicine, IA, USA,"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2004,12]]},"reference":[{"key":"e_1_2_1_1_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1956.tb12766.x"},{"key":"e_1_2_1_2_1","first-page":"550","article-title":"An immunofluorescence assay for double-stranded DNA antibodies using the                         Crithidia luciliae kinetoplast as a double-stranded DNA substrate","volume":"91","author":"Sontheimer RD","year":"1978","unstructured":"Sontheimer RD , Gilliam JN. 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