{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T02:45:17Z","timestamp":1787021117546,"version":"build-2736575974"},"reference-count":15,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2004,2,1]],"date-time":"2004-02-01T00:00:00Z","timestamp":1075593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Lupus"],"published-print":{"date-parts":[[2004,2]]},"abstract":"<jats:p>Hypercalcemia is a common electrolyte abnormality with a wide differential diagnosis. Primary hyperparathyroidismand malignancy are the most frequent causes, accounting for more than 90% of cases. We report the case of a woman presenting with symptomatic severe hypercalcemia, who was subsequently diagnosed with systemic lupus erythematosus (SLE) due to the presence of arthritis, lymphopenia, antinuclear antibodies (ANA), anti-DNA and anti-Ro antibodies and low C3 levels. After acute treatment with intravenous fluids, steroids, diuretics and pamidronate, calcium levels corrected and have remained normal on low-dose prednisone.Five similar cases have been reported in the literature. Thus, SLE is an uncommon cause of hypercalcemia, which can also be the presenting feature of lupus.<\/jats:p>","DOI":"10.1191\/0961203304lu476cr","type":"journal-article","created":{"date-parts":[[2004,2,4]],"date-time":"2004-02-04T18:47:17Z","timestamp":1075920437000},"page":"132-134","source":"Crossref","is-referenced-by-count":11,"title":["Systemic lupus erythematosus presenting as acute symptomatic hypercalcemia"],"prefix":"10.1177","volume":"13","author":[{"given":"J G","family":"Erdozain","sequence":"first","affiliation":[{"name":"Service of Internal Medicine, Hospital de Cruces, Universidad del Pais                         Vasco\/Euskal Herriko Unibertsitatea, Bizkaia, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M V","family":"Egurbide","sequence":"additional","affiliation":[{"name":"Service of Internal Medicine, Hospital de Cruces, Universidad del Pais                         Vasco\/Euskal Herriko Unibertsitatea, Bizkaia, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G","family":"Ruiz-Irastorza","sequence":"additional","affiliation":[{"name":"Service of Internal Medicine, Hospital de Cruces, Universidad del Pais                         Vasco\/Euskal Herriko Unibertsitatea, Bizkaia, Spain,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J","family":"Ojanguren","sequence":"additional","affiliation":[{"name":"Service of Haematology, Hospital de Galdakao Bizkaia, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C","family":"Aguirre","sequence":"additional","affiliation":[{"name":"Service of Internal Medicine, Hospital de Cruces, Universidad del Pais                         Vasco\/Euskal Herriko Unibertsitatea, Bizkaia, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2004,2,1]]},"reference":[{"key":"atypb1","volume-title":"Clinical Essentials of Calcium and Skeletal Disorders","author":"Deftos LJ.","year":"1998"},{"key":"atypb2","first-page":"2205","volume-title":"Harrison\u2019s Principles of Internal Medicine","author":"Potts JT.","year":"2001","edition":"15"},{"key":"atypb3","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780251101"},{"key":"atypb4","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780400928"},{"key":"atypb5","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(91)90802-V"},{"key":"atypb6","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780391217"},{"key":"atypb7","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(96)90344-X"},{"key":"atypb8","first-page":"485","volume":"67","author":"Gazzaruso C","year":"2000","journal-title":"Joint Bone Spine"},{"key":"atypb9","doi-asserted-by":"publisher","DOI":"10.1007\/s100670170088"},{"key":"atypb10","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199004193221603"},{"key":"atypb11","first-page":"1155","volume":"13","author":"Goni M-H","year":"1993","journal-title":"Anticancer Resp"},{"key":"atypb12","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/105.4.487"},{"key":"atypb13","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199004193221613"},{"key":"atypb14","doi-asserted-by":"publisher","DOI":"10.1210\/edrv-9-4-450"},{"key":"atypb15","doi-asserted-by":"publisher","DOI":"10.3109\/10408369509084687"}],"container-title":["Lupus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1191\/0961203304lu476cr","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1191\/0961203304lu476cr","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,27]],"date-time":"2025-02-27T14:09:59Z","timestamp":1740665399000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1191\/0961203304lu476cr"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,2]]},"references-count":15,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2004,2]]}},"alternative-id":["10.1191\/0961203304lu476cr"],"URL":"https:\/\/doi.org\/10.1191\/0961203304lu476cr","relation":{},"ISSN":["0961-2033","1477-0962"],"issn-type":[{"value":"0961-2033","type":"print"},{"value":"1477-0962","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004,2]]}}}