{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T09:32:31Z","timestamp":1771666351222,"version":"3.50.1"},"reference-count":44,"publisher":"SAGE Publications","issue":"10","license":[{"start":{"date-parts":[[2005,10,1]],"date-time":"2005-10-01T00:00:00Z","timestamp":1128124800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Lupus"],"published-print":{"date-parts":[[2005,10]]},"abstract":"<jats:p> The objective of this study was to analyse clinical and serological associations of anti-Ki antibodies. Thirty-five patients with anti-Ki antibodies, detected by CIE, selected from laboratory routine, were studied. All patients were affected by autoimmune diseases: SLE and pSS were the most frequent diagnoses. The cohort was constituted by 27 female and eight males. Main clinical features were skin involvement (60%), xerophtalmia (48.6%), Raynaud\u2019s phenomenon (43%), photosensitivity (34%), xerostomia (31.4%). CNS involvement was present in four (11.4%) and renal disease in seven cases (20%). ANA, anti-dsDNA and RF were detected in 100%, 60% and 34.5%. In SLE, anti-Ki was detected in 6% of cases, more frequently in males compared to other SLE patients without anti-Ki ( P &lt; 0.004). Nineteen anti-Ki positive patients affected by SLE showed more frequently malar rash and multiple autoantibody specificities compared to 16 anti-Ki positive patients with other diseases ( P = 0.044 and P = 0.0003, respectively). Our study confirms a preferential occurrence of anti-Ki antibodies in patients with sicca and skin involvement. Malar rash and multiple ANA specificities were significantly associated with SLE compared to other diseases in our study. Anti-Ki were detected in 6% of patients with SLE with a significant prevalence in males. <\/jats:p>","DOI":"10.1191\/0961203305lu2226oa","type":"journal-article","created":{"date-parts":[[2005,10,20]],"date-time":"2005-10-20T21:02:19Z","timestamp":1129842139000},"page":"837-841","source":"Crossref","is-referenced-by-count":11,"title":["Clinical and serological features of 35 patients with anti-Ki autoantibodies"],"prefix":"10.1177","volume":"14","author":[{"given":"I","family":"Cavazzana","sequence":"first","affiliation":[{"name":"Rheumatology Unit and Chair, Spedali Civili, Brescia, Italy,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F","family":"Franceschini","sequence":"additional","affiliation":[{"name":"Rheumatology Unit and Chair, Spedali Civili, Brescia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C","family":"Vassalini","sequence":"additional","affiliation":[{"name":"Rheumatology Unit and Chair, Spedali Civili, Brescia, 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