{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T10:04:17Z","timestamp":1760954657469,"version":"3.38.0"},"reference-count":10,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2004,6,1]],"date-time":"2004-06-01T00:00:00Z","timestamp":1086048000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mult Scler"],"published-print":{"date-parts":[[2004,6]]},"abstract":"<jats:p> Patients with MS exhibit a broad diversity of ocular motor syndromes. We describe a patient with relapsing-remitting MS who developed an unusual variation of the dorsal midbrain syndrome, character ized by monocular convergent-retraction nystagmus in the right eye, accompanied by divergent-retraction nystagmus in the fellow eye upon attempted upward gaze. Examination also revealed a skew deviation with a left hyperdeviation and severe adductio n limitation in the left eye during attempted right gaze. We propose that a left INO accounted for the inability of the left eye to adduct (and result in convergent-retraction) during attempted upward saccades. We consider the patho physiologic mechanisms responsible for our observations and review important details of the dorsal midbrain ocular motor circuitr y. <\/jats:p>","DOI":"10.1191\/1352458504ms1043oa","type":"journal-article","created":{"date-parts":[[2004,5,12]],"date-time":"2004-05-12T22:51:03Z","timestamp":1084402263000},"page":"322-325","source":"Crossref","is-referenced-by-count":14,"title":["An unusual variant of the dorsal midbrain syndrome in MS: clinical                 characteristics and pathophysiologic mechanisms"],"prefix":"10.1177","volume":"10","author":[{"given":"Elliot M","family":"Frohman","sequence":"first","affiliation":[{"name":"Department of Neurology, University of Texas Southwestern Medical Center                         at Dallas, Dallas, TX, USA, Department of Ophthalmology, University of Texas                         Southwestern Medical Center at Dallas, Dallas, TX, USA,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard B","family":"Dewey","sequence":"additional","affiliation":[{"name":"Department of Neurology, University of Texas Southwestern Medical Center                         at Dallas, Dallas, TX, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Teresa C","family":"Frohman","sequence":"additional","affiliation":[{"name":"Department of Neurology, University of Texas Southwestern Medical Center                         at Dallas, Dallas, TX, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2004,6,1]]},"reference":[{"key":"atypb1","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1966.00470160086012"},{"key":"atypb2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410110116"},{"key":"atypb3","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.54.10.1985"},{"key":"atypb4","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.40.4.684"},{"key":"atypb5","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/102.3.497"},{"key":"atypb6","doi-asserted-by":"publisher","DOI":"10.1002\/ana.1263"},{"key":"atypb7","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1963.00960050458005"},{"key":"atypb8","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410360304"},{"key":"atypb9","doi-asserted-by":"publisher","DOI":"10.1126\/science.2047862"},{"key":"atypb10","first-page":"455","volume":"1","author":"Zee DS.","year":"1992","journal-title":"Bailliere\u2019s Clin Neurol"}],"container-title":["Multiple Sclerosis Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1191\/1352458504ms1043oa","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1191\/1352458504ms1043oa","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,2]],"date-time":"2025-03-02T02:20:30Z","timestamp":1740882030000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1191\/1352458504ms1043oa"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,6]]},"references-count":10,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2004,6]]}},"alternative-id":["10.1191\/1352458504ms1043oa"],"URL":"https:\/\/doi.org\/10.1191\/1352458504ms1043oa","relation":{},"ISSN":["1352-4585","1477-0970"],"issn-type":[{"type":"print","value":"1352-4585"},{"type":"electronic","value":"1477-0970"}],"subject":[],"published":{"date-parts":[[2004,6]]}}}