{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T15:28:59Z","timestamp":1774020539133,"version":"3.50.1"},"reference-count":10,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2004,10,1]],"date-time":"2004-10-01T00:00:00Z","timestamp":1096588800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mult Scler"],"published-print":{"date-parts":[[2004,10]]},"abstract":"<jats:p> Substantially more women than men develop multiple sclerosis (MS), but information about the effects of MS and gender-specific issues such as pregnancy, breastfeeding, menstruation and hormone use is lacking. A survey study of neurologists\u2019 practice patterns was undertaken to elicit information about gender-specific topics and the use of disease-modifying MS therapies (DMT) including the interferons and glatiramer acetate (GA). A total of 147 surveys were returned. Half of respondents require patients to discontinue DMT during pregnancy, while 35% encourage discontinuation. Among those who allow patients to continue therapy, half consider GA to be safer during pregnancy than the interferons. Nearly 86% of respondents do not use DMT in patients who are breastfeeding. Among the 11% who actually prescribe during breastfeeding, most recommend GA. Neurologists generally leave the decision to breastfeed up to patients, and most refer patients to obstetrician\/gynaecologists for counselling about contraception or hormone replacement therapy. The survey results described here provide insight into how neurologists manage reproductive health issues among women with MS. <\/jats:p>","DOI":"10.1191\/1352458504ms1083oa","type":"journal-article","created":{"date-parts":[[2004,8,17]],"date-time":"2004-08-17T22:56:23Z","timestamp":1092783383000},"page":"582-588","source":"Crossref","is-referenced-by-count":46,"title":["Multiple sclerosis gender issues: clinical practices of women neurologists"],"prefix":"10.1177","volume":"10","author":[{"given":"P K","family":"Coyle","sequence":"first","affiliation":[{"name":"MS Comprehensive Care Center, SUNY at Stony Brook, New York, NY, USA,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S","family":"Christie","sequence":"additional","affiliation":[{"name":"MS Clinic, Ottawa General Hospital, Ottawa, Ontario, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P","family":"Fodor","sequence":"additional","affiliation":[{"name":"Colorado Springs Neurological Associates and MS Center of Southern                         Colorado, Colorado Springs, CO, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K","family":"Fuchs","sequence":"additional","affiliation":[{"name":"James Q. Miller MS Clinic, University of Virginia, Charlottesville, VA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B","family":"Giesser","sequence":"additional","affiliation":[{"name":"Reed Neurological Research Center, UCLA School of Medicine, Los Angeles,                         CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Gutierrez","sequence":"additional","affiliation":[{"name":"Louisiana State University Health Science, New Orleans, LA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"Lynn","sequence":"additional","affiliation":[{"name":"Department of Neurology, Ohio State University, Columbus, OH, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B","family":"Weinstock-Guttman","sequence":"additional","affiliation":[{"name":"Department of Neurology, Buffalo General Hospital, Buffalo, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L","family":"Pardo","sequence":"additional","affiliation":[{"name":"University of Kansas Medical Center and Teva Neuroscience, Kansas City,                         MO, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Women Neurologists MS Initiative (WNMSI)","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2004,10,1]]},"reference":[{"key":"atypb1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.58.1.136"},{"key":"atypb2","volume-title":"The MS information sourcebook","author":"National Multiple Sclerosis Society","year":"2001"},{"key":"atypb3","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199807303390501"},{"key":"atypb4","unstructured":"Code of Federal Regulations, Title 21, Volume 4, Parts 200- 299. Revised                 April 1, 1997. US Government Printing Office. 21CFR201.57; 22-23."},{"key":"atypb5","volume-title":"Betaseron\u00ae package information","year":"2002"},{"key":"atypb6","doi-asserted-by":"publisher","DOI":"10.1089\/15246090050020709"},{"key":"atypb7","doi-asserted-by":"publisher","DOI":"10.1016\/S1068-607X(98)00152-8"},{"key":"atypb8","doi-asserted-by":"publisher","DOI":"10.1159\/000066166"},{"key":"atypb9","doi-asserted-by":"publisher","DOI":"10.1177\/135245850000602S05"},{"key":"atypb10","doi-asserted-by":"publisher","DOI":"10.1016\/S0301-2115(98)00231-0"}],"container-title":["Multiple Sclerosis Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1191\/1352458504ms1083oa","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1191\/1352458504ms1083oa","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T15:32:51Z","timestamp":1740843171000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1191\/1352458504ms1083oa"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,10]]},"references-count":10,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2004,10]]}},"alternative-id":["10.1191\/1352458504ms1083oa"],"URL":"https:\/\/doi.org\/10.1191\/1352458504ms1083oa","relation":{},"ISSN":["1352-4585","1477-0970"],"issn-type":[{"value":"1352-4585","type":"print"},{"value":"1477-0970","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004,10]]}}}