{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T20:42:06Z","timestamp":1792701726192,"version":"4.5.0"},"reference-count":19,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2005,4,1]],"date-time":"2005-04-01T00:00:00Z","timestamp":1112313600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mult Scler"],"published-print":{"date-parts":[[2005,4]]},"abstract":"<jats:p>Anxiety and phobia frequently prevent patients with multiple sclerosis (MS) from self-injecting their injectable disease-modifying medications. This small, randomized, controlled trial tested the efficacy of a six-session nurse-administered programme to teach self-injection to patients with MS, who, due to anxiety or phobia, were unable to self-inject their injectable medications. Participants were 30 patients with MS who were prescribed interferon beta-1a (IFN\u03b2-1a) administered via weekly intramuscular injection. All patients were unable to self-inject due to anxiety or phobia. Patients were randomized to either the six-session Self-Injection Anxiety Therapy (SIAT) or a control telephone support condition modelled on the support programme offered by the manufacturer of IFN\u03b2-1a. Four patients dropped out of SIATwhile three dropped out of the control condition. Eight patients receiving SIAT, compared to three control patients, were able to self-inject after six weeks of treatment. SIAT patients were significantly more likely to achieve self-injection at treatment cessation, compared to telephone control patients, in completer analyses (p=0.022), however, this only reached a trend in intent-to-treat analyses (p=0.058). These findings suggest that SIAT is a potentially valuable intervention to teach self-injection skills to injection phobic and anxious patients, and should be investigated more thoroughly in a larger clinical trial.<\/jats:p>","DOI":"10.1191\/1352458505ms1146oa","type":"journal-article","created":{"date-parts":[[2005,3,8]],"date-time":"2005-03-08T20:34:05Z","timestamp":1110314045000},"page":"182-185","source":"Crossref","is-referenced-by-count":44,"title":["Self-Injection Anxiety Training: a treatment for patients unable to                 self-inject injectable medications"],"prefix":"10.1177","volume":"11","author":[{"given":"David C","family":"Mohr","sequence":"first","affiliation":[{"name":"University of California, San Francisco, CA, USA,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Darcy","family":"Cox","sequence":"additional","affiliation":[{"name":"University of California, San Francisco, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natalia","family":"Merluzzi","sequence":"additional","affiliation":[{"name":"University of California, San Francisco, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2005,4,1]]},"reference":[{"key":"atypb1","doi-asserted-by":"publisher","DOI":"10.1207\/S15324796ABM2302_7"},{"key":"atypb2","doi-asserted-by":"publisher","DOI":"10.2165\/00137696-200301030-00005"},{"key":"atypb3","volume-title":"Diagnostic and statistical manual of mental disorders","author":"American Psychiatric Association","year":"1994"},{"key":"atypb4","doi-asserted-by":"publisher","DOI":"10.1016\/0010-440X(69)90022-4"},{"key":"atypb5","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291798007144"},{"key":"atypb6","doi-asserted-by":"publisher","DOI":"10.1097\/00007611-199307000-00003"},{"key":"atypb7","doi-asserted-by":"publisher","DOI":"10.1037\/0021-843X.91.4.280"},{"key":"atypb8","doi-asserted-by":"publisher","DOI":"10.1177\/135245859600200502"},{"key":"atypb9","doi-asserted-by":"publisher","DOI":"10.1016\/S0005-7916(02)00011-3"},{"key":"atypb10","volume-title":"A compendium of neuropsychological tests: administration, norms, and commentary","author":"Spreen O","year":"1998"},{"key":"atypb11","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.41.5.685"},{"key":"atypb12","volume-title":"Stroop Color and Word Test","author":"Golden CJ.","year":"1978"},{"key":"atypb13","volume-title":"Wisconsin Card Sorting Test manual","author":"Heaton RK.","year":"1981"},{"key":"atypb14","doi-asserted-by":"publisher","DOI":"10.1177\/135245859900500409"},{"key":"atypb15","doi-asserted-by":"publisher","DOI":"10.1037\/0022-006X.68.1.46"},{"key":"atypb16","doi-asserted-by":"publisher","DOI":"10.1093\/clipsy.7.2.189"},{"key":"atypb17","volume-title":"The practice of behavior therapy","author":"Wolpe J.","year":"1973"},{"key":"atypb18","volume-title":"Cognitive therapy: basic principles and applications","author":"Leahy RL.","year":"1996"},{"key":"atypb19","volume-title":"Structured Clinical Interview for DSM-IV Axis I disorders-patient","author":"First MB","year":"1995"}],"container-title":["Multiple Sclerosis Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1191\/1352458505ms1146oa","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1191\/1352458505ms1146oa","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T09:34:37Z","timestamp":1740821677000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1191\/1352458505ms1146oa"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,4]]},"references-count":19,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2005,4]]}},"alternative-id":["10.1191\/1352458505ms1146oa"],"URL":"https:\/\/doi.org\/10.1191\/1352458505ms1146oa","relation":{},"ISSN":["1352-4585","1477-0970"],"issn-type":[{"value":"1352-4585","type":"print"},{"value":"1477-0970","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,4]]}}}