{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T23:10:05Z","timestamp":1784675405055,"version":"3.55.0"},"reference-count":18,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2005,10,1]],"date-time":"2005-10-01T00:00:00Z","timestamp":1128124800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mult Scler"],"published-print":{"date-parts":[[2005,10]]},"abstract":"<jats:p> We describe two cases of neuromyelitis optica (NMO) with clinical and radiographically confirmed features of hypothalamic involvement, in the absence of other parenchymal brain lesions. Their course is otherwise typical of Devic\u2019s form of NMO. A review of the literature identifies additional cases of NMO in which clinical features attributable to under-recognized dysfunction of the hypothalamic-pituitary axis were present. We propose that the currently accepted criteria for the diagnosis of NMO could be revisited to recognize the possibility of lesions developing within hypothalamic structures. <\/jats:p>","DOI":"10.1191\/1352458505ms1200cr","type":"journal-article","created":{"date-parts":[[2005,8,20]],"date-time":"2005-08-20T21:32:16Z","timestamp":1124573536000},"page":"617-621","source":"Crossref","is-referenced-by-count":107,"title":["Neuromyelitis optica with hypothalamic involvement"],"prefix":"10.1177","volume":"11","author":[{"given":"Alexandre Y","family":"Poppe","sequence":"first","affiliation":[{"name":"McGill University Health Centre, The Montreal Neurological Institute and                         Hospital, 3801 University Street, Montreal, Quebec, Canada H3A 2B4"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yves","family":"Lapierre","sequence":"additional","affiliation":[{"name":"McGill University Health Centre, The Montreal Neurological Institute and                         Hospital, 3801 University Street, Montreal, Quebec, Canada H3A 2B4"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denis","family":"Melan\u00e7on","sequence":"additional","affiliation":[{"name":"McGill University Health Centre, The Montreal Neurological Institute and                         Hospital, 3801 University Street, Montreal, Quebec, Canada H3A 2B4"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diane","family":"Lowden","sequence":"additional","affiliation":[{"name":"McGill University Health Centre, The Montreal Neurological Institute and                         Hospital, 3801 University Street, Montreal, Quebec, Canada H3A 2B4"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucy","family":"Wardell","sequence":"additional","affiliation":[{"name":"McGill University Health Centre, The Montreal Neurological Institute and                         Hospital, 3801 University Street, Montreal, Quebec, Canada H3A 2B4"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louise M","family":"Fullerton","sequence":"additional","affiliation":[{"name":"McGill University Health Centre, The Montreal Neurological Institute and                         Hospital, 3801 University Street, Montreal, Quebec, Canada H3A 2B4"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amit","family":"Bar-Or","sequence":"additional","affiliation":[{"name":"Neuroimmunology Unit, The Montreal Neurological Institute and Hospital,                         McGill University, 3801 University Street, Montreal, Quebec, Canada H3A 2B4,"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2005,10,1]]},"reference":[{"key":"atypb1","unstructured":"Devic ME. 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