{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T06:01:53Z","timestamp":1767852113343,"version":"3.49.0"},"reference-count":20,"publisher":"Royal College of Psychiatrists","issue":"2","license":[{"start":{"date-parts":[[2021,2,24]],"date-time":"2021-02-24T00:00:00Z","timestamp":1614124800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["BJPsych open"],"published-print":{"date-parts":[[2021,3]]},"abstract":"\n\t Background<\/jats:title>\n\t A large amount of literature surrounds the differences between dissociative neurological symptom disorder with non-epileptic seizures (DNSD-S) and epilepsy.<\/jats:p>\n\t <\/jats:sec>\n\t \n\t Aims<\/jats:title>\n\t To explore the research gap on phenotypic differences between DNSD-S and other psychiatric disorders.<\/jats:p>\n\t <\/jats:sec>\n\t \n\t Method<\/jats:title>\n\t We conducted a case\u2013control study of 1860 patients (620 patients with DNSD-S and 1240 controls with other psychiatric disorders) seen at the South London and Maudsley Hospital NHS Trust between 2007 and 2019.<\/jats:p>\n\t <\/jats:sec>\n\t \n\t Results<\/jats:title>\n\t Compared with the controls, the patients with DNSD-S were more likely to be female (76 v.<\/jats:italic> 47%, P<\/jats:italic> < 0.001), of White ethnicity (77 v.<\/jats:italic> 60%, P<\/jats:italic> < 0.001), married (34 v.<\/jats:italic> 14%, P<\/jats:italic> < 0.001) and living in areas of lower socioeconomic status (\u22123.79, 95% CI \u22122.62 to \u22124.96, P<\/jats:italic> < 0.001). Two peaks for age at diagnosis were observed for DNSD-S: the early 20s and late 40s. After 31 years of age, men's chance of being diagnosed with DNSD-S increased from 19 to 28% (P<\/jats:italic> = 0.009). People with DNSD-S presented more commonly with a history of a neurological episodic or paroxysmal disorder (OR = 12, 95% CI 7.82\u201320.26), another dissociative disorder (OR = 10, 95% CI 1.64\u2013 65.95) or unclassified signs or symptoms (OR = 4, 95% CI 2.61\u20136.43). Neither anxiety, depression nor other somatoform disorders predicted subsequent diagnosis of DNSD-S, and controls had a larger proportion of preceding psychiatric diagnoses than patients with DNSD-S (65 v.<\/jats:italic> 49%, P<\/jats:italic> < 0.001).<\/jats:p>\n\t <\/jats:sec>\n\t \n\t Conclusions<\/jats:title>\n\t This is the first study comparing demographic and phenotypic correlates of patients with DNSD-S against a large cohort of psychiatric patients. These data will inform development and drive service needs in psychiatry for people with DNSD-S.<\/jats:p>\n\t <\/jats:sec>","DOI":"10.1192\/bjo.2021.18","type":"journal-article","created":{"date-parts":[[2021,2,24]],"date-time":"2021-02-24T09:31:36Z","timestamp":1614159096000},"update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":1,"title":["Demographic and clinical phenotypic differences between people with dissociative seizures and those with other psychiatric disorders"],"prefix":"10.1192","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9367-2970","authenticated-orcid":false,"given":"Abigail","family":"Smakowski","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacob S.","family":"Bird","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Megan","family":"Pritchard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9415-3395","authenticated-orcid":false,"given":"Marco","family":"Mula","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"170","published-online":{"date-parts":[[2021,2,24]]},"reference":[{"key":"S2056472421000181_ref15","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2015-008721"},{"key":"S2056472421000181_ref11","doi-asserted-by":"publisher","DOI":"10.1111\/epi.12356"},{"key":"S2056472421000181_ref17","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000223320.94812.7a"},{"key":"S2056472421000181_ref5","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-801772-2.00025-4"},{"key":"S2056472421000181_ref4","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.2009.197996"},{"key":"S2056472421000181_ref18","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.2003.032169"},{"key":"S2056472421000181_ref6","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e3181e39658"},{"key":"S2056472421000181_ref2","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-801772-2.00005-9"},{"key":"S2056472421000181_ref8","doi-asserted-by":"publisher","DOI":"10.1111\/epi.16350"},{"key":"S2056472421000181_ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.seizure.2007.12.010"},{"key":"S2056472421000181_ref9","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.57.5.915"},{"key":"S2056472421000181_ref10","doi-asserted-by":"publisher","DOI":"10.1176\/appi.psy.48.3.230"},{"key":"S2056472421000181_ref13","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000113755.11398.90"},{"key":"S2056472421000181_ref1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yebeh.2015.03.015"},{"key":"S2056472421000181_ref16","unstructured":"16 Department for Communities and Local Government. English Indices of Deprivation 2015. Gov.uk, 2015 (https:\/\/www.gov.uk\/government\/statistics\/english-indices-of-deprivation-2015)."},{"key":"S2056472421000181_ref14","doi-asserted-by":"publisher","DOI":"10.1186\/1471-244X-9-51"},{"key":"S2056472421000181_ref20","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291716003093"},{"key":"S2056472421000181_ref19","doi-asserted-by":"publisher","DOI":"10.1016\/j.eplepsyres.2003.11.004"},{"key":"S2056472421000181_ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.yebeh.2013.05.004"},{"key":"S2056472421000181_ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.yebeh.2007.11.006"}],"container-title":["BJPsych Open"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S2056472421000181","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,2,24]],"date-time":"2021-02-24T09:31:43Z","timestamp":1614159103000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S2056472421000181\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2,24]]},"references-count":20,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2021,3]]}},"alternative-id":["S2056472421000181"],"URL":"https:\/\/doi.org\/10.1192\/bjo.2021.18","relation":{},"ISSN":["2056-4724"],"issn-type":[{"value":"2056-4724","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,2,24]]},"assertion":[{"value":"Copyright \u00a9 The Author(s), 2021. Published by Cambridge University Press on behalf of the Royal College of Psychiatrists","name":"copyright","label":"Copyright","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article, distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives licence (http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is unaltered and is properly cited. The written permission of Cambridge University Press must be obtained for commercial re-use or in order to create a derivative work.","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}],"article-number":"e61"}}