{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T02:44:38Z","timestamp":1787021078092,"version":"build-2736575974"},"reference-count":36,"publisher":"Royal College of Psychiatrists","issue":"4","license":[{"start":{"date-parts":[[2021,7,22]],"date-time":"2021-07-22T00:00:00Z","timestamp":1626912000000},"content-version":"unspecified","delay-in-days":21,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"publisher","award":["PJT-153429"],"award-info":[{"award-number":["PJT-153429"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["BJPsych open"],"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:sec id=\"S2056472421009716_sec_a1\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Exposure to traumatic events is both a risk factor for substance use and an adverse outcome of substance use disorders. Identifying and managing post-traumatic stress disorder (PTSD) in patients with addiction requires attention.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S2056472421009716_sec_a2\">\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>To examine the lifetime prevalence of traumatic events and past-month prevalence of PSTD in patients treated for opioid use disorder, and explore the association between trauma, PTSD and treatment outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S2056472421009716_sec_a3\" sec-type=\"methods\">\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>\n                      Participants (\n                      <jats:italic>n<\/jats:italic>\n                      = 674) receiving methadone treatment in 20 community clinics across Ontario, Canada, were administered the Mini-International Neuropsychiatric Interview to identify self-reported traumatic events and PTSD. Drug use was measured for 12 months by urine drug screens.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S2056472421009716_sec_a4\" sec-type=\"results\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Eleven per cent of participants met past-month criteria for PTSD (\n                      <jats:italic>n<\/jats:italic>\n                      = 72), and 48% reported history of traumatic events with no current PTSD (\n                      <jats:italic>n<\/jats:italic>\n                      = 323). Participants with PTSD were more likely to be female (odds ratio 2.13, 95% CI 1.20\u20133.76) and less likely to be employed (odds ratio 0.31, 95% CI 0.16\u20130.61) or married (odds ratio 0.51, 95% CI 0.26\u20130.90) than those with no trauma history. Antidepressants (39\n                      <jats:italic>v<\/jats:italic>\n                      . 24%) and benzodiazepines (36\n                      <jats:italic>v<\/jats:italic>\n                      . 18%) were differentially prescribed to patients with and without PTSD. Length of time in treatment and opioid use were not associated with trauma; however, suicidal ideation was more common in PTSD (odds ratio 2.29, 95% CI 1.04\u20135.01).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S2056472421009716_sec_a5\" sec-type=\"conclusions\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Trauma and PTSD are prevalent among patients with opioid use disorder, and consideration of trauma symptoms and associated characteristics is warranted. Patients with and without comorbid PTSD differ clinically and psychosocially, highlighting the relevance of integrating addiction and mental health services for this population.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1192\/bjo.2021.971","type":"journal-article","created":{"date-parts":[[2021,7,22]],"date-time":"2021-07-22T06:50:42Z","timestamp":1626936642000},"update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":11,"title":["Trauma and post-traumatic stress disorder in patients treated for opioid use disorder: findings from a 12-month cohort study"],"prefix":"10.1192","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7406-4056","authenticated-orcid":false,"given":"Tea","family":"Rosic","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vivian Y. 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Six-month posttreatment outcomes of substance use disordered patients with and without comorbid PTSD. 13th Annual Meeting of the International Society for Traumatic Stress Studies (Montreal, Quebec, Canada, 6\u201310 November, 1997). 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Published by Cambridge University Press on behalf of the Royal College of Psychiatrists","name":"copyright","label":"Copyright","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http:\/\/creativecommons.org\/licenses\/by\/4.0\/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}],"article-number":"e138"}}