{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T01:17:32Z","timestamp":1778635052450,"version":"3.51.4"},"reference-count":35,"publisher":"Royal College of Psychiatrists","issue":"6","license":[{"start":{"date-parts":[[2023,10,10]],"date-time":"2023-10-10T00:00:00Z","timestamp":1696896000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000272","name":"National Institute for Health and Care Research","doi-asserted-by":"publisher","award":["NIHR200120"],"award-info":[{"award-number":["NIHR200120"]}],"id":[{"id":"10.13039\/501100000272","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["BJPsych open"],"published-print":{"date-parts":[[2023,11]]},"abstract":"<jats:sec id=\"S2056472423005744_sec_a1\">\n\t    <jats:title>Background<\/jats:title>\n\t    <jats:p>People with intellectual disability often experience aggressive challenging behaviour and mental health issues. It can be difficult to identify those who are at higher risk of adverse clinical outcomes when in clinical care.<\/jats:p>\n\t  <\/jats:sec>\n\t  <jats:sec id=\"S2056472423005744_sec_a2\">\n\t    <jats:title>Aims<\/jats:title>\n\t    <jats:p>To characterise potential subgroups in adults with intellectual disability referred to mental health services in those presenting with aggressive behaviour or common mental disorders (CMDs).<\/jats:p>\n\t  <\/jats:sec>\n\t  <jats:sec id=\"S2056472423005744_sec_a3\" sec-type=\"methods\">\n\t    <jats:title>Method<\/jats:title>\n\t    <jats:p>There were 836 adults (\u226518 years) with intellectual disability and a record of aggressive challenging behaviour, and 205 patients with intellectual disability and CMDs, who were seen in specialist mental health services over a 5-year period. Cluster analysis was used to define patient characteristics associated with clinical outcome.<\/jats:p>\n\t  <\/jats:sec>\n\t  <jats:sec id=\"S2056472423005744_sec_a4\" sec-type=\"results\">\n\t    <jats:title>Results<\/jats:title>\n\t    <jats:p>Distinct patient groups with differentiated profiles were observed in people with intellectual disability displaying aggressive challenging behaviour, and in those presenting with CMDs. Characteristics of the aggressive behaviour group who experienced adverse outcomes included being &lt;30 years old, being male, more mentions of aggression and agitation in their clinical record, a diagnosis of pervasive developmental disorder and prescription of psychotropic medication. Characteristics of the CMD cluster that experienced adverse clinical outcomes were being older, being a White male, having a mild intellectual disability and physical health concerns.<\/jats:p>\n\t  <\/jats:sec>\n\t  <jats:sec id=\"S2056472423005744_sec_a5\" sec-type=\"conclusions\">\n\t    <jats:title>Conclusions<\/jats:title>\n\t    <jats:p>People with intellectual disability who experience adverse clinical outcomes can be identified with a cluster analysis approach of common features, but differ by clinical presentation. This could be used not only to stratify this clinically heterogeneous population in terms of response to interventions, but also improve precision in the development of tailored interventions.<\/jats:p>\n\t  <\/jats:sec>","DOI":"10.1192\/bjo.2023.574","type":"journal-article","created":{"date-parts":[[2023,10,10]],"date-time":"2023-10-10T00:53:58Z","timestamp":1696899238000},"update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":6,"title":["Identifying individuals with intellectual disability who access mental health support and are at high risk for adverse clinical outcomes: cohort study"],"prefix":"10.1192","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6596-2145","authenticated-orcid":false,"given":"R. 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