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After 3\u00bd weeks treatment, patients with plasma levels within a median range (630 to 900 nmol\/1) showed better responses to the drug than patients with plasma levels outside this range.<\/jats:p><jats:p>There were no statistically significant correlations between plasma levels and side effect scores or \u2018corrected\u2019 side effect scores (scores after subtracting pre-treatment values) for the group at any time after starting the treatment. But we found positive correlations between plasma levels and \u2018corrected\u2019 side effect scores for the neurotic subgroup after 14 and 21 days of treatment. Other correlations between plasma levels and side effect scores were non-significant.<\/jats:p>","DOI":"10.1192\/bjp.128.4.384","type":"journal-article","created":{"date-parts":[[2008,8,12]],"date-time":"2008-08-12T22:35:43Z","timestamp":1218580543000},"page":"384-390","source":"Crossref","is-referenced-by-count":46,"title":["Plasma Concentrations of Protriptyline and Clinical Effects in Depressed Women"],"prefix":"10.1192","volume":"128","author":[{"given":"S. F.","family":"Whyte","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. J.","family":"Macdonald","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G. J.","family":"Naylor","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. 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