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Demented subjects showed significantly more CT evidence of cerebral atrophy than non-demented subjects, but there was considerable overlap. Although patients with a history or clinical signs of cerebral infarction were specifically excluded, such infarcts were found more often in CT scans of the dementia subjects than in the others, particularly when the diastolic blood pressure was raised. When correlating cognitive impairment with CT changes, ventricular size emerged as more important in the dementia patients, in contrast to the controls, in whom cortical atrophy was related to lower scores on a cognitive test. Other interesting findings included an inverse relationship between cortical atrophy and paranoid delusions.<\/jats:p>","DOI":"10.1192\/bjp.136.3.256","type":"journal-article","created":{"date-parts":[[2008,8,12]],"date-time":"2008-08-12T22:35:43Z","timestamp":1218580543000},"page":"256-269","source":"Crossref","is-referenced-by-count":174,"title":["Computed Tomography in the Elderly 2. Senile Dementia: Diagnosis and Functional Impairment"],"prefix":"10.1192","volume":"136","author":[{"given":"Robin J.","family":"Jacoby","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raymond","family":"Levy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"170","published-online":{"date-parts":[[2018,1,29]]},"reference":[{"key":"S000712500004530X_ref13","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.18.2.129"},{"key":"S000712500004530X_ref6","volume-title":"In Alzheimer's Disease: Senile Dementia and Related Disorders","author":"Constantinides","year":"1978"},{"key":"S000712500004530X_ref2","unstructured":"Bergmann K. (1979) Problems of early diagnosis. 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In preparation."},{"key":"S000712500004530X_ref11","first-page":"157","article-title":"The reliability of computerized transaxial tomography in diagnosing acute traumatic intracranial haematoma","volume":"63","author":"Galbraith","year":"1976","journal-title":"British Journal of Surgery"},{"key":"S000712500004530X_ref16","doi-asserted-by":"publisher","DOI":"10.1007\/BF00496982"},{"key":"S000712500004530X_ref30","volume-title":"DPM Dissertation","author":"McCormick","year":"1962"},{"key":"S000712500004530X_ref21","doi-asserted-by":"publisher","DOI":"10.1148\/116.1.85"},{"key":"S000712500004530X_ref10","doi-asserted-by":"publisher","DOI":"10.1097\/00004728-197809000-00110"},{"key":"S000712500004530X_ref1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.26.11.1011"},{"key":"S000712500004530X_ref24","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.136.3.270"},{"key":"S000712500004530X_ref39","volume-title":"The Wechsler Manual.","author":"Wechsler","year":"1955"},{"key":"S000712500004530X_ref18","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.134.5.494"},{"key":"S000712500004530X_ref23","article-title":"Computed tomography in the elderly: 1. 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