{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T13:23:22Z","timestamp":1760189002332},"reference-count":10,"publisher":"Royal College of Psychiatrists","issue":"5","license":[{"start":{"date-parts":[[2018,1,29]],"date-time":"2018-01-29T00:00:00Z","timestamp":1517184000000},"content-version":"unspecified","delay-in-days":13238,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Br J Psychiatry"],"published-print":{"date-parts":[[1981,11]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Anterior pituitary response to TRH 200 \u03bcg i.v. was studied in ten chronic schizophrenic patients during long-term neuroleptic treatment. Nine patients had normal prolactin (PRL) response as compared with controls but in one the response was blunted; one patient had an exaggerated response. Prolactin increment was higher following TRH than haloperidol challenge. No growth hormone (GH) response to TRH was found and TSH responses were comparable to controls.<\/jats:p>","DOI":"10.1192\/bjp.139.5.404","type":"journal-article","created":{"date-parts":[[2008,8,12]],"date-time":"2008-08-12T19:20:52Z","timestamp":1218568852000},"page":"404-407","source":"Crossref","is-referenced-by-count":14,"title":["II. The TRH Test"],"prefix":"10.1192","volume":"139","author":[{"given":"Louise E.","family":"Braddock","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isabel M.","family":"Blake","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"170","published-online":{"date-parts":[[2018,1,29]]},"reference":[{"key":"S0007125000134294_ref6","doi-asserted-by":"publisher","DOI":"10.1210\/jcem-33-6-996"},{"key":"S0007125000134294_ref3","doi-asserted-by":"publisher","DOI":"10.1210\/jcem-43-3-638"},{"key":"S0007125000134294_ref1","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.124.5.420"},{"key":"S0007125000134294_ref10","first-page":"59","article-title":"Effect of long-term neuroleptic treatment on dopamine tubero-infundibular system: Development of tolerance?","volume":"3","author":"Naber","year":"1979","journal-title":"Communication in Psychopharmacology"},{"key":"S0007125000134294_ref9","article-title":"Combined effect of pimozide and thyroliberin (TRH) on serum prolactin and thyroid stimulating hormone (TSH) in man","volume":"43","author":"Linnoila","year":"1978","journal-title":"Acta Pharmacologica et Toxicologica (Copenhagen)"},{"key":"S0007125000134294_ref7","doi-asserted-by":"publisher","DOI":"10.1210\/jcem-36-6-1069"},{"key":"S0007125000134294_ref5","article-title":"Radioimmunoassay of human serum thyrotropin","volume":"i","author":"Hall","year":"1971","journal-title":"British Medical Journal"},{"key":"S0007125000134294_ref8","doi-asserted-by":"publisher","DOI":"10.1007\/BF00431832"},{"key":"S0007125000134294_ref2","doi-asserted-by":"publisher","DOI":"10.1016\/0006-291X(71)90441-4"},{"key":"S0007125000134294_ref4","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1978.01770250110011"}],"container-title":["British Journal of Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0007125000134294","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,25]],"date-time":"2019-05-25T15:25:55Z","timestamp":1558797955000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0007125000134294\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1981,11]]},"references-count":10,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1981,11]]}},"alternative-id":["S0007125000134294"],"URL":"https:\/\/doi.org\/10.1192\/bjp.139.5.404","relation":{},"ISSN":["0007-1250","1472-1465"],"issn-type":[{"value":"0007-1250","type":"print"},{"value":"1472-1465","type":"electronic"}],"subject":[],"published":{"date-parts":[[1981,11]]}}}