{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T10:07:54Z","timestamp":1790503674937,"version":"4.1.0"},"reference-count":21,"publisher":"Royal College of Psychiatrists","issue":"3","license":[{"start":{"date-parts":[[2018,1,29]],"date-time":"2018-01-29T00:00:00Z","timestamp":1517184000000},"content-version":"unspecified","delay-in-days":12569,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Br J Psychiatry"],"published-print":{"date-parts":[[1983,9]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:p>\n                    Fifteen patients with bilateral hemisphere brain injury secondary to thromboembolic stroke or trauma were evaluated for depression, cognitive impairment, and functional physical impairment. Analysis of CT scans and standardized mood scales revealed that patients with\n                    <jats:italic>left anterior<\/jats:italic>\n                    brain injury were significantly more depressed than patients without such injury. Depression severity was directly and significantly correlated with left lesion proximity to the frontal pole. Left lesion age, lesion temporal sequence, right lesion location, cognitive impairment, and functional physical impairment did not significantly correlate with depression. Depressive symptomatology previously shown to be associated with single left frontal lobe lesions appeared to dominate post-brain injury psychopathology regardless of location or temporal sequence of other brain lesions.\n                  <\/jats:p>","DOI":"10.1192\/bjp.143.3.266","type":"journal-article","created":{"date-parts":[[2008,8,12]],"date-time":"2008-08-12T19:20:52Z","timestamp":1218568852000},"page":"266-273","source":"Crossref","is-referenced-by-count":95,"title":["Mood Change following Bilateral Hemisphere Brain Injury"],"prefix":"10.1192","volume":"143","author":[{"given":"John R.","family":"Lipsey","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert G.","family":"Robinson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Godfrey D.","family":"Pearlson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Krishan","family":"Rao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas R.","family":"Price","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"170","published-online":{"date-parts":[[2018,1,29]]},"reference":[{"key":"S0007125000117544_ref21","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1965.01720310065008"},{"key":"S0007125000117544_ref19","doi-asserted-by":"publisher","DOI":"10.1037\/0033-2909.89.1.19"},{"key":"S0007125000117544_ref16","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(80)90557-0"},{"key":"S0007125000117544_ref15","doi-asserted-by":"publisher","DOI":"10.1016\/0093-934X(81)90080-8"},{"key":"S0007125000117544_ref10","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.23.1.56"},{"key":"S0007125000117544_ref9","article-title":"The organisation of language and the brain.","volume":"170","author":"Gechwind","year":"1970","journal-title":"Science"},{"key":"S0007125000117544_ref8","doi-asserted-by":"publisher","DOI":"10.1016\/S0010-9452(72)80026-1"},{"key":"S0007125000117544_ref7","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.40.10.1018"},{"key":"S0007125000117544_ref4","doi-asserted-by":"publisher","DOI":"10.1038\/261690a0"},{"key":"S0007125000117544_ref11","volume-title":"Psychiatrie, ein Lehrbuch fur Studierende und Artzte.","author":"Kraepelin","year":"1904"},{"key":"S0007125000117544_ref20","first-page":"56","volume-title":"Computed Tomography and Cerebral Infarction.","author":"Valk","year":"1980"},{"key":"S0007125000117544_ref13","first-page":"83","volume-title":"Neurologic Emergencies: Recognition and Management","author":"Price","year":"1980"},{"key":"S0007125000117544_ref3","article-title":"The mental and emotional results of strokes.","volume":"78","author":"Charatan","year":"1978","journal-title":"New York State Journal of Medicine"},{"key":"S0007125000117544_ref5","article-title":"On certain aspects of the localization of the cerebral systems regulating and determining emotion.","volume":"14","author":"Flor-Henry","year":"1979","journal-title":"Biological Psychiatry"},{"key":"S0007125000117544_ref2","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-662-36478-9"},{"key":"S0007125000117544_ref18","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410090506"},{"key":"S0007125000117544_ref1","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.123.5.555"},{"key":"S0007125000117544_ref14","doi-asserted-by":"publisher","DOI":"10.1126\/science.462179"},{"key":"S0007125000117544_ref12","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(81)91303-2"},{"key":"S0007125000117544_ref17","doi-asserted-by":"crossref","unstructured":"Robinson R. G. , Kubos K. L. , Starr L. B. , Rao K. & Price T. R. (1983) Mood disorders in stroke patients: importance of lesion location. Brain. In press.","DOI":"10.1016\/0010-440X(83)90024-X"},{"key":"S0007125000117544_ref6","article-title":"A practical method for grading the cognitive state of patients for the clinician.","volume":"12","author":"Folstein","year":"1975","journal-title":"Journal of Psychiatric Research"}],"container-title":["British Journal of Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0007125000117544","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,23]],"date-time":"2019-05-23T18:37:12Z","timestamp":1558636632000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0007125000117544\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1983,9]]},"references-count":21,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1983,9]]}},"alternative-id":["S0007125000117544"],"URL":"https:\/\/doi.org\/10.1192\/bjp.143.3.266","relation":{},"ISSN":["0007-1250","1472-1465"],"issn-type":[{"value":"0007-1250","type":"print"},{"value":"1472-1465","type":"electronic"}],"subject":[],"published":{"date-parts":[[1983,9]]}}}