{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T17:18:24Z","timestamp":1760548704764},"reference-count":9,"publisher":"Royal College of Psychiatrists","issue":"3","license":[{"start":{"date-parts":[[2018,1,2]],"date-time":"2018-01-02T00:00:00Z","timestamp":1514851200000},"content-version":"unspecified","delay-in-days":10715,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Br J Psychiatry"],"published-print":{"date-parts":[[1988,9]]},"abstract":"<jats:p>Depot neuroleptics are now commonly used for maintenance therapy of schizophrenia. Their physicochemical composition makes them ideal for such use because they are long-acting and show stable blood levels for prolonged periods. Their absorption from the site of injection may, however, be affected by local muscle factors. This paper describes three such factors in relation to fluphenazine decanoate: varying the site of injection; massage of the injection site; and effects of muscular exercise. Our results suggest that fluphenazine pharmacokinetics are not significantly affected by any of these factors.<\/jats:p>","DOI":"10.1192\/bjp.153.3.382","type":"journal-article","created":{"date-parts":[[2008,8,12]],"date-time":"2008-08-12T19:43:23Z","timestamp":1218570203000},"page":"382-384","source":"Crossref","is-referenced-by-count":13,"title":["Plasma Levels of Fluphenazine Decanoate"],"prefix":"10.1192","volume":"153","author":[{"given":"Som D.","family":"Soni","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Wiles","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. A.","family":"Schiff","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. S.","family":"Bamrah","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"170","published-online":{"date-parts":[[2018,1,2]]},"reference":[{"key":"S0007125000223052_ref1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198208053070607"},{"key":"S0007125000223052_ref6","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0773.1980.tb01856.x"},{"key":"S0007125000223052_ref3","unstructured":"Diem E. & Lentner C. (eds) (1970) Documenta Geigy Scientific Tables (7th ed), p. 561."},{"key":"S0007125000223052_ref9","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0447.1978.tb06929.x"},{"key":"S0007125000223052_ref4","first-page":"179","article-title":"Effect of massage, shortwave diathermy and ultrasound upon 133Xe disappearance rate from muscle and subcutaneous tissue in human calf","volume":"5","author":"Hansen","year":"1973","journal-title":"Scandinavian Journal of Rehabilitation Medicine"},{"key":"S0007125000223052_ref2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(72)90442-0"},{"key":"S0007125000223052_ref5","doi-asserted-by":"publisher","DOI":"10.1002\/j.1552-4604.1974.tb02293.x"},{"key":"S0007125000223052_ref7","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2125.1978.tb01636.x"},{"key":"S0007125000223052_ref8","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2125.1979.tb01045.x"}],"container-title":["British Journal of Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0007125000223052","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,20]],"date-time":"2019-05-20T15:19:03Z","timestamp":1558365543000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0007125000223052\/type\/journal_article"}},"subtitle":["Effects of site of injection, massage and muscle activity"],"short-title":[],"issued":{"date-parts":[[1988,9]]},"references-count":9,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1988,9]]}},"alternative-id":["S0007125000223052"],"URL":"https:\/\/doi.org\/10.1192\/bjp.153.3.382","relation":{},"ISSN":["0007-1250","1472-1465"],"issn-type":[{"value":"0007-1250","type":"print"},{"value":"1472-1465","type":"electronic"}],"subject":[],"published":{"date-parts":[[1988,9]]}}}