{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,5]],"date-time":"2025-10-05T16:56:08Z","timestamp":1759683368417},"reference-count":66,"publisher":"Royal College of Psychiatrists","issue":"1","license":[{"start":{"date-parts":[[2018,1,2]],"date-time":"2018-01-02T00:00:00Z","timestamp":1514851200000},"content-version":"unspecified","delay-in-days":10593,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Br J Psychiatry"],"published-print":{"date-parts":[[1989,1]]},"abstract":"<jats:p>Abnormal neuroendocrine responses have been found in depression and eating disorders. It remains unclear whether these reflect an underlying shared biology or epiphenomena. To evaluate this further, we conducted the 1 mg DST and the TSH response to 500 \u03bcg i.v. TRH in normal-weight bulimics and controls. Bulimics (<jats:italic>n<\/jats:italic>= 18) demonstrated significantly more DST non-suppression (45%) than controls (18%;<jats:italic>n<\/jats:italic>= 20). In the bulimic group, non-suppressors were significantly thinner than suppressors, but did not differ from them on any measure of depression. Bulimics (<jats:italic>n<\/jats:italic>= 19) and controls (<jats:italic>n<\/jats:italic>= 12) responded similarly without blunting on the TSH response to TRH. These data suggest that DST non-suppression may be related to non-specific variables such as weight. Bulimics do not demonstrate TSH blunting as found in some depressed patients. These tests do not support evidence for a biological link between these disorders.<\/jats:p>","DOI":"10.1192\/bjp.154.1.86","type":"journal-article","created":{"date-parts":[[2008,8,12]],"date-time":"2008-08-12T20:01:46Z","timestamp":1218571306000},"page":"86-92","source":"Crossref","is-referenced-by-count":18,"title":["The DST and TRH Test in Bulimia Nervosa"],"prefix":"10.1192","volume":"154","author":[{"given":"Allan S.","family":"Kaplan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul E.","family":"Garfinkel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gregory 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