{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,21]],"date-time":"2026-01-21T04:01:58Z","timestamp":1768968118626,"version":"3.49.0"},"reference-count":24,"publisher":"Royal College of Psychiatrists","issue":"4","license":[{"start":{"date-parts":[[2018,1,3]],"date-time":"2018-01-03T00:00:00Z","timestamp":1514937600000},"content-version":"unspecified","delay-in-days":10139,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Br J Psychiatry"],"published-print":{"date-parts":[[1990,4]]},"abstract":"<jats:p>Acute non-anaphylactic reactions to procaine penicillin include fear of death, sensations of disintegration, perceived changes of body shape, and visual and auditory hallucinations. Fragments of the original reaction experience, or elaborations of it, feature prominently in a chronic syndrome which persists if the initial reaction is not supported emotionally or professionally. The cultural acceptance of the reality of \u2018mysterious' forces played a role in the syndrome. Compatible diagnostic labels were panic disorder, post-traumatic disorder, mixed phobic disorder, and depressive illness. The observed period prevalence rate is 5.9 per 1000.<\/jats:p>","DOI":"10.1192\/bjp.156.4.554","type":"journal-article","created":{"date-parts":[[2008,8,13]],"date-time":"2008-08-13T00:13:05Z","timestamp":1218586385000},"page":"554-559","source":"Crossref","is-referenced-by-count":16,"title":["Acute Psychotic Reactions and Stress Response Syndromes Following Intramuscular Aqueous Procaine Penicillin"],"prefix":"10.1192","volume":"156","author":[{"given":"S. T. C.","family":"Ilechukwu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"170","published-online":{"date-parts":[[2018,1,3]]},"reference":[{"key":"S0007125000178791_ref23","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1967.00300040049008"},{"key":"S0007125000178791_ref24","doi-asserted-by":"crossref","first-page":"1271","DOI":"10.1097\/00007611-196611000-00005","article-title":"Acute psychotic reactions to aqueous procaine penicillin","volume":"59","author":"Utley","year":"1966","journal-title":"South African Medical Journal"},{"key":"S0007125000178791_ref4","first-page":"129","article-title":"Acute psychotic reactions after injection of procaine penicillin","volume":"35","author":"Bjornberg","year":"1960","journal-title":"Acta Psychiatrica et Neurologica Scandinavica"},{"key":"S0007125000178791_ref16","doi-asserted-by":"crossref","first-page":"1433","DOI":"10.1176\/ajp.137.11.1433","article-title":"Stress response syndrome occurring after delirium","volume":"137","author":"Mackenzie","year":"1980","journal-title":"American Journal of Psychiatry"},{"key":"S0007125000178791_ref6","first-page":"223","article-title":"Non-allergic adverse reaction to aqueous procaine penicillin","volume":"72","author":"Downham","year":"1973","journal-title":"Michigan Medicine"},{"key":"S0007125000178791_ref5","doi-asserted-by":"publisher","DOI":"10.1055\/s-0028-1111976"},{"key":"S0007125000178791_ref22","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1953.63690150004009c"},{"key":"S0007125000178791_ref12","first-page":"201","article-title":"Acute side-reactions to penicillin reactions","volume":"171","author":"Hoigne","year":"1962","journal-title":"Acta Medica Scandinavica"},{"key":"S0007125000178791_ref8","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-81-3-358"},{"key":"S0007125000178791_ref18","first-page":"185","article-title":"The kindling phenomenon and a clinical application: the procaine test","volume":"10","author":"Pollock","year":"1985","journal-title":"Psychiatric Journal of the University of Ottawa"},{"key":"S0007125000178791_ref11","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4886(75)90146-6"},{"key":"S0007125000178791_ref2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(51)91439-0"},{"key":"S0007125000178791_ref17","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(74)93303-0"},{"key":"S0007125000178791_ref15","volume-title":"The Use and Abuse of Drugs and Chemicals in Tropical Africa. Proceedings of the 1973 Annual Scientific Conference of the East African Research Council","author":"Mabadeje","year":"1974"},{"key":"S0007125000178791_ref9","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197408012910503"},{"key":"S0007125000178791_ref21","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1176\/ajp.144.2.159","article-title":"\u201cDoom anxiety\u201d and delirium in lidocaine toxicity","volume":"144","author":"Saraway","year":"1987","journal-title":"American Journal of Psychiatry"},{"key":"S0007125000178791_ref10","doi-asserted-by":"crossref","first-page":"15","DOI":"10.5694\/j.1326-5377.1960.tb86919.x","article-title":"Immediate reactions to procaine penicillin injection with a report of 3 cases","volume":"ii","author":"Grounds","year":"1960","journal-title":"Medical Journal of Australia"},{"key":"S0007125000178791_ref7","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bdj.4804379"},{"key":"S0007125000178791_ref3","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(54)90053-7"},{"key":"S0007125000178791_ref14","first-page":"109","article-title":"Pseudoanaphylactic reaction to procaine pencillin and kindling","volume":"12","author":"Ilechukwu","year":"1987","journal-title":"Psychiatric Journal of the University of Ottawa"},{"key":"S0007125000178791_ref1","volume-title":"Diagnostic and Statistical Manual of Mental Disorders","year":"1980"},{"key":"S0007125000178791_ref20","volume-title":"Critical Dictionary of Psychoanalysis.","author":"Rycroft","year":"1968"},{"key":"S0007125000178791_ref13","first-page":"1350","article-title":"Anaphylaktischer Schock and akute nichtallergische Reactionen nach Procaine-Penicillin","volume":"89","author":"Hoigne","year":"1959","journal-title":"Schweizerische Medizinische Wochenschrift"},{"key":"S0007125000178791_ref19","first-page":"110","article-title":"Response to Ilechukwa, S.T.C.","volume":"12","author":"Pollock","year":"1987","journal-title":"vide supra. Psychiatric Journal of the University of Ottawa"}],"container-title":["British Journal of Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0007125000178791","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,29]],"date-time":"2024-02-29T07:18:58Z","timestamp":1709191138000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0007125000178791\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1990,4]]},"references-count":24,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1990,4]]}},"alternative-id":["S0007125000178791"],"URL":"https:\/\/doi.org\/10.1192\/bjp.156.4.554","relation":{},"ISSN":["0007-1250","1472-1465"],"issn-type":[{"value":"0007-1250","type":"print"},{"value":"1472-1465","type":"electronic"}],"subject":[],"published":{"date-parts":[[1990,4]]}}}