{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T09:07:50Z","timestamp":1780045670321,"version":"3.53.1"},"reference-count":13,"publisher":"Royal College of Psychiatrists","issue":"2","license":[{"start":{"date-parts":[[2018,1,2]],"date-time":"2018-01-02T00:00:00Z","timestamp":1514851200000},"content-version":"unspecified","delay-in-days":9285,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Br J Psychiatry"],"published-print":{"date-parts":[[1992,8]]},"abstract":"<jats:p>The occurrence of neuroleptic malignant syndrome (NMS) was studied prospectively in two series of consecutive psychiatric in-patients (<jats:italic>n<\/jats:italic> = 223). The first group (<jats:italic>n<\/jats:italic> = 120) suffered from schizophrenia and was treated only with haloperidol. The second group (<jats:italic>n<\/jats:italic>=103) was treated with diverse neuroleptics. All patients were on a single antipsychotic agent with no anticholinergic drug as prophylaxis. The incidence of full NMS per admission and first neuroleptic exposure was 5\/223 (2.2%). Patients with bipolar affective disorder and those treated with injections were significantly over-represented in the NMS group.<\/jats:p>","DOI":"10.1192\/bjp.161.2.254","type":"journal-article","created":{"date-parts":[[2008,10,15]],"date-time":"2008-10-15T00:56:07Z","timestamp":1224032167000},"page":"254-257","source":"Crossref","is-referenced-by-count":47,"title":["Risk for Definite Neuroleptic Malignant 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