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Depression (DSM\u2013III\u2013R major depression, partially resolved major depression, and dysthymia) was present in 11 (18%) of the patients and was associated with impaired physical and cognitive functioning, greater age, residence in an institution, absence of a close personal relationship, and larger original brain lesion. Of these variables, only functional dependence (odds ratio 16.4; confidence interval 1.6\u2013170), larger lesion volume (6.6; 1\u201350), and female sex (8; 1.1\u201356) remained significantly associated with depression after controlling for all other variables. We conclude that depression in long-term survivors of stroke has many of the same associations as depression in non-stroke elderly populations. Depression in long-term stroke survivors may also be associated with larger original brain lesions, although this requires confirmation in a prospective study.<\/jats:p>","DOI":"10.1192\/bjp.164.3.380","type":"journal-article","created":{"date-parts":[[2008,10,15]],"date-time":"2008-10-15T05:26:25Z","timestamp":1224048385000},"page":"380-386","source":"Crossref","is-referenced-by-count":83,"title":["Depressive Disorders in Long-Term Survivors of 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