{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,9,4]],"date-time":"2024-09-04T20:58:33Z","timestamp":1725483513941},"reference-count":29,"publisher":"Royal College of Psychiatrists","issue":"5","license":[{"start":{"date-parts":[[2018,1,3]],"date-time":"2018-01-03T00:00:00Z","timestamp":1514937600000},"content-version":"unspecified","delay-in-days":7552,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Br J Psychiatry"],"published-print":{"date-parts":[[1997,5]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>The relationship between midline structural defects and schizophrenia remains unclear, although a number of neuroradiological studies have reported an association between schizophrenia and a range of anomalies.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>Three patients are reported, each diagnosed with schizophrenia and neuroradiological evidence of midline structural anomalies. MRI scans are reported in conjunction with performance over a range of neuropsychological tests designed to assess frontal and lateralised cognitive functions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Evidence of anterior dysfunction was present in all three cases, while on an individual basis patients displayed varying patterns of preserved and dysfunctional cognitive processing.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The reported findings raise a number of interesting issues regarding the nature of hemispheric involvement in schizophrenia.<\/jats:p><\/jats:sec>","DOI":"10.1192\/bjp.170.5.416","type":"journal-article","created":{"date-parts":[[2008,10,15]],"date-time":"2008-10-15T05:36:56Z","timestamp":1224049016000},"page":"416-421","source":"Crossref","is-referenced-by-count":8,"title":["A neuropsychological perspective on three schizophrenic patients with midline structural defects"],"prefix":"10.1192","volume":"170","author":[{"given":"N. 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