{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T07:18:52Z","timestamp":1791357532272,"version":"4.3.1"},"reference-count":27,"publisher":"Royal College of Psychiatrists","issue":"3","license":[{"start":{"date-parts":[[2018,1,2]],"date-time":"2018-01-02T00:00:00Z","timestamp":1514851200000},"content-version":"unspecified","delay-in-days":5602,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Br J Psychiatry"],"published-print":{"date-parts":[[2002,9]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Data on the duration of major depressive episodes (MDE) in the general population are sparse.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>To assess the duration of MDE and its clinical and socio-demographic determinants in a study group drawn from the general population with newly originated episodes of major depression.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>\n                      The Netherlands Mental Health Survey and Incidence Study is a prospective epidemiological survey in the adult population (\n                      <jats:italic>n=7076<\/jats:italic>\n                      ), using the Composite International Diagnostic Interview. Duration of MDE over 2 years was assessed with a Life Chart Interview.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The median duration of MDE was 3.0 months; 50% of participants recovered within 3 months, 63% within 6 months, 76% within 12 months and nearly 20% had not recovered at 24 months. Determinants of persistence were severity of depression and comorbid dysthymia. A recurrent episode predicted shorter duration.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Although half of those affected with MDE recovered rapidly, the risk of chronicity (duration 24months or more) was considerable. This underlines the necessity of diagnosing and treating those at risk.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1192\/bjp.181.3.208","type":"journal-article","created":{"date-parts":[[2002,8,30]],"date-time":"2002-08-30T17:42:12Z","timestamp":1030729332000},"page":"208-213","source":"Crossref","is-referenced-by-count":408,"title":["Duration of major depressive episodes in the general population: Results from the Netherlands Mental Health Survey and Incidence Study (NEMESIS)"],"prefix":"10.1192","volume":"181","author":[{"given":"Jan","family":"Spijker","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ron","family":"De Graaf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rob V","family":"Bijl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aartjan T. 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