{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T23:09:20Z","timestamp":1789859360601,"version":"4.0.1"},"reference-count":31,"publisher":"Royal College of Psychiatrists","issue":"4","license":[{"start":{"date-parts":[[2018,1,2]],"date-time":"2018-01-02T00:00:00Z","timestamp":1514851200000},"content-version":"unspecified","delay-in-days":5390,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Br J Psychiatry"],"published-print":{"date-parts":[[2003,4]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Evidence for the efficacy of cognitive\u2013behavioural therapy for schizophrenia is promising but evidence for clinical effectiveness is limited.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aims<\/jats:title><jats:p>To test the effectiveness of cognitive\u2013behavioural therapy delivered by clinical nurse specialists in routine practice.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>Of 274 referrals, 66 were allocated randomly to 9 months of treatment as usual (TAU), cognitive\u2013behavioural therapy plus TAU (CBT) or supportive psychotherapy plus TAU (SPT) and followed up for 3 months.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Treatment effects were modest but the CBT condition gave significantly greater improvement in overall symptom severity than the SPT or TAU conditions combined (<jats:italic>F<\/jats:italic> (1,53)=4.14; <jats:italic>P<\/jats:italic>=0.05). Both the CBT and SPT conditions combined gave significantly greater improvement in severity of delusions than did the TAU condition (<jats:italic>F<\/jats:italic> (1,53)=4.83; <jats:italic>P<\/jats:italic>=0.03). Clinically significant improvements were achieved by 7\/21 in the CBT condition (33%), 3\/19 in the SPT condition (16%) and 2\/17 in the TAU condition (12%).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Cognitive\u2013behavioural therapy delivered by clinical nurse specialists is a helpful adjunct to routine care for some people with chronic psychosis.<\/jats:p><\/jats:sec>","DOI":"10.1192\/bjp.182.4.303","type":"journal-article","created":{"date-parts":[[2003,4,1]],"date-time":"2003-04-01T01:34:58Z","timestamp":1049160898000},"page":"303-311","source":"Crossref","is-referenced-by-count":125,"title":["Tayside\u2013Fife clinical trial of cognitive\u2013behavioural therapy for medication-resistant psychotic symptoms"],"prefix":"10.1192","volume":"182","author":[{"given":"Robert C.","family":"Durham","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Moyra","family":"Guthrie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. Victor","family":"Morton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David A.","family":"Reid","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linda R.","family":"Treliving","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Fowler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ranald R.","family":"MacDonald","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"170","published-online":{"date-parts":[[2018,1,2]]},"reference":[{"key":"S0007125000228274_ref31","volume-title":"The ICD\u201310 Classification of Mental and Behavioural Disorders","year":"1992"},{"key":"S0007125000228274_ref29","doi-asserted-by":"publisher","DOI":"10.1037\/0022-006X.54.3.381"},{"key":"S0007125000228274_ref27","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.317.7154.303"},{"key":"S0007125000228274_ref26","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.162.4.524"},{"key":"S0007125000228274_ref19","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.171.4.319"},{"key":"S0007125000228274_ref25","first-page":"147","volume-title":"Innovations in the Psychological Management of Schizophrenia","author":"Tarrier","year":"1992"},{"key":"S0007125000228274_ref24","doi-asserted-by":"publisher","DOI":"10.1017\/S1352465802003077"},{"key":"S0007125000228274_ref21","first-page":"260","article-title":"The revised Helping Alliance Questionnaire (HAQ\u201311)","volume":"5","author":"Luborsky","year":"1996","journal-title":"Journal of Psychotherapy Practice and Research"},{"key":"S0007125000228274_ref18","volume-title":"Cognitive\u2013Behavioural Therapy of Schizophrenia","author":"Kingdon","year":"1994"},{"key":"S0007125000228274_ref15","first-page":"24","volume-title":"Research Methods in Psychiatry","author":"Johnson","year":"1992"},{"key":"S0007125000228274_ref12","volume-title":"Unbearable Affect: A Guide to the Psychotherapy of Psychosis","author":"Garfield","year":"1995"},{"key":"S0007125000228274_ref8","first-page":"43","volume-title":"Outcome and Innovation in Psychological Treatment of Schizophrenia","author":"Drake","year":"1998"},{"key":"S0007125000228274_ref6","volume-title":"Cochrane Library, issue 4","author":"Cormac","year":"2002"},{"key":"S0007125000228274_ref4","doi-asserted-by":"publisher","DOI":"10.4324\/9780203298398"},{"key":"S0007125000228274_ref13","volume-title":"Assessment Manual for Psychopharmacology","author":"Guy","year":"1976"},{"key":"S0007125000228274_ref20","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.173.1.61"},{"key":"S0007125000228274_ref14","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291799008661"},{"key":"S0007125000228274_ref11","volume-title":"Cognitive Behaviour Therapy for People with Psychosis: A Clinical Handbook","author":"Fowler","year":"1995"},{"key":"S0007125000228274_ref9","doi-asserted-by":"publisher","DOI":"10.1080\/713680258"},{"key":"S0007125000228274_ref7","doi-asserted-by":"publisher","DOI":"10.1177\/000306519404200205"},{"key":"S0007125000228274_ref16","first-page":"35","article-title":"Treatment-resistant schizophrenic patients","volume":"57","author":"Kane","year":"1996","journal-title":"Journal of Clinical Psychiatry"},{"key":"S0007125000228274_ref30","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.159.2.255"},{"key":"S0007125000228274_ref22","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291702005895"},{"key":"S0007125000228274_ref10","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1976.01770060086012"},{"key":"S0007125000228274_ref5","doi-asserted-by":"publisher","DOI":"10.1037\/0033-2909.112.1.155"},{"key":"S0007125000228274_ref2","doi-asserted-by":"publisher","DOI":"10.1192\/pb.21.4.224"},{"key":"S0007125000228274_ref3","volume-title":"The Assessment of Psychoses: A Practical Handbook","author":"Barnes","year":"1994"},{"key":"S0007125000228274_ref23","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.57.2.165"},{"key":"S0007125000228274_ref1","volume-title":"Diagnostic and Statistical Manual of Mental Disorders","year":"1994"},{"key":"S0007125000228274_ref17","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/13.2.261"},{"key":"S0007125000228274_ref28","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.180.6.523"}],"container-title":["British Journal of Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0007125000228274","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,6]],"date-time":"2019-05-06T23:26:34Z","timestamp":1557185194000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0007125000228274\/type\/journal_article"}},"subtitle":["Results to 3-month follow-up"],"short-title":[],"issued":{"date-parts":[[2003,4]]},"references-count":31,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2003,4]]}},"alternative-id":["S0007125000228274"],"URL":"https:\/\/doi.org\/10.1192\/bjp.182.4.303","relation":{},"ISSN":["0007-1250","1472-1465"],"issn-type":[{"value":"0007-1250","type":"print"},{"value":"1472-1465","type":"electronic"}],"subject":[],"published":{"date-parts":[[2003,4]]}}}