{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T11:17:27Z","timestamp":1790421447230,"version":"4.1.0"},"reference-count":25,"publisher":"Royal College of Psychiatrists","issue":"4","license":[{"start":{"date-parts":[[2018,1,2]],"date-time":"2018-01-02T00:00:00Z","timestamp":1514851200000},"content-version":"unspecified","delay-in-days":4659,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Br J Psychiatry"],"published-print":{"date-parts":[[2005,4]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>There is increasing evidence that cognitive\u2013behavioural therapy can be an effective intervention for patients experiencing drug-refractory positive symptoms of schizophrenia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aims<\/jats:title><jats:p>To investigate the effects of cognitive\u2013behavioural therapy on in-patients with treatment-refractory psychotic symptoms.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>Manualised therapy was compared with supportive counselling in a randomised controlled study. Both interventions were delivered by experienced psychologists over 16 sessions of treatment. Therapy fidelity was assessed by two independent raters. Participants underwent masked assessment at baseline, after treatment and at 6 months' follow-up. Main outcome measures were the Positive and Negative Syndrome Scale and the Psychotic Symptoms Rating Scale. The analysis was by intention to treat.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Participants receiving cognitive\u2013behavioural therapy had improved with regard to auditory hallucinations and illness insight at the post-treatment assessment, but these findings were not maintained at follow-up.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Cognitive\u2013behavioural therapy showed modest short-term benefits over supportive counselling for treatment-refractory positive symptoms of schizophrenia.<\/jats:p><\/jats:sec>","DOI":"10.1192\/bjp.186.4.324","type":"journal-article","created":{"date-parts":[[2005,3,31]],"date-time":"2005-03-31T23:18:36Z","timestamp":1112311116000},"page":"324-330","source":"Crossref","is-referenced-by-count":127,"title":["Cognitive\u2013behavioural therapy for refractory psychotic symptoms of schizophrenia resistant to atypical antipsychotic medication"],"prefix":"10.1192","volume":"186","author":[{"given":"Lucia R.","family":"Valmaggia","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"van der Gaag","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas","family":"Tarrier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marieke","family":"Pijnenborg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cees J.","family":"Slooff","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"170","published-online":{"date-parts":[[2018,1,2]]},"reference":[{"key":"S0007125000165845_ref23","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.174.6.500"},{"key":"S0007125000165845_ref22","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.317.7154.303"},{"key":"S0007125000165845_ref21","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.162.4.524"},{"key":"S0007125000165845_ref20","volume-title":"SPSS for Windows, Release 10","year":"1999"},{"key":"S0007125000165845_ref19","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.57.2.165"},{"key":"S0007125000165845_ref17","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291702005895"},{"key":"S0007125000165845_ref16","volume-title":"Schizophrenia. 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